E. Gurgul-Convey

发表

Enhancement of homocysteine toxicity to insulin-secreting BRIN-BD11 cells in combination with alloxan.

S. Lenzen, M. Elsner, P. Flatt, 2012, The Journal of endocrinology.

Physiological characterization of the human EndoC-βH1 β-cell line.

S. Lenzen, M. Kaminski, E. Gurgul-Convey, 2015, Biochemical and biophysical research communications.

Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria

S. Lenzen, S. Lortz, I. Mehmeti, 2011, Journal of Molecular Medicine.

IL-1β hampers glucose-stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric oxide.

Ann Saada, I. Raz, Genya Aharon-Hananel, 2014, American journal of physiology. Endocrinology and metabolism.

Induction of the intrinsic apoptosis pathway in insulin-secreting cells is dependent on oxidative damage of mitochondria but independent of caspase-12 activation.

S. Lenzen, S. Lortz, I. Mehmeti, 2011, Biochimica et biophysica acta.

Effects of the novel mitochondrial protein mimitin in insulin-secreting cells.

L. Skalniak, S. Lenzen, J. Jura, 2012, The Biochemical journal.

Mechanism of prostacyclin-induced potentiation of glucose-induced insulin secretion.

S. Lenzen, K. Hanzelka, E. Gurgul-Convey, 2012, Endocrinology.

Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells.

S. Lenzen, M. Elsner, E. Gurgul-Convey, 2006, Free radical biology & medicine.

Relation between triketone structure, generation of reactive oxygen species, and selective toxicity of the diabetogenic agent alloxan.

S. Lenzen, M. Elsner, E. Gurgul-Convey, 2008, Antioxidants & redox signaling.

Differential effects of proinflammatory cytokines on cell death and ER stress in insulin-secreting INS1E cells and the involvement of nitric oxide.

S. Lenzen, E. Gurgul-Convey, Stella Kacheva, 2011, Cytokine.

Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression.

A. Boschero, E. Carneiro, S. Lenzen, 2009, Free radical biology & medicine.

Limited GADD45 alpha expression and function in IL-1 beta toxicity towards insulin-producing cells

L. Skalniak, J. Jura, A. Skalniak, 2013 .

Limited GADD45α expression and function in IL-1β toxicity towards insulin-producing cells.

L. Skalniak, J. Jura, A. Skalniak, 2013, Acta biochimica Polonica.

Protection against Cytokine Toxicity through Endoplasmic Reticulum and Mitochondrial Stress Prevention by Prostacyclin Synthase Overexpression in Insulin-producing Cells*

S. Lenzen, E. Gurgul-Convey, 2010, The Journal of Biological Chemistry.

Is there a role for neuronal nitric oxide synthase (nNOS) in cytokine toxicity to pancreatic beta cells?

S. Lenzen, K. Hanzelka, E. Gurgul-Convey, 2012, Nitric oxide : biology and chemistry.

Interaction between pro-inflammatory and anti-inflammatory cytokines in insulin-producing cells.

S. Lenzen, M. Elsner, K. L. Souza, 2008, The Journal of endocrinology.

Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity.

S. Lenzen, P. Flatt, N. Mcclenaghan, 2016, Chemico-biological interactions.

Importance of mitochondrial superoxide dismutase expression in insulin-producing cells for the toxicity of reactive oxygen species and proinflammatory cytokines

S. Lenzen, M. Tiedge, S. Lortz, 2005, Diabetologia.

Immunometabolism in type 2 diabetes mellitus: tissue-specific interactions

M. Marzec, E. Gurgul-Convey, Erika Pinheiro-Machado, 2020, Archives of medical science : AMS.

Proinflammatory cytokines induce rapid, NO-independent apoptosis, expression of chemotactic mediators and interleukin-32 secretion in human pluripotent stem cell-derived beta cells

T. Yoshimoto, O. Naujok, Rabea Dettmer, 2022, Diabetologia.

To Be or Not to Be: The Divergent Action and Metabolism of Sphingosine-1 Phosphate in Pancreatic Beta-Cells in Response to Cytokines and Fatty Acids

E. Gurgul-Convey, 2022, International journal of molecular sciences.

Sphingolipids in Type 1 Diabetes: Focus on Beta-Cells

E. Gurgul-Convey, 2020, Cells.

Sensitivity profile of the human EndoC-βH1 beta cell line to proinflammatory cytokines

T. Plötz, S. Lenzen, A. Jörns, 2016, Diabetologia.

Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

S. Lenzen, O. Naujok, S. Lortz, 2013, Diabetologia.

Sphingosine-1 Phosphate Lyase Regulates Sensitivity of Pancreatic Beta-Cells to Lipotoxicity

T. Plötz, M. Gräler, Yadi Tang, 2021, International journal of molecular sciences.

Progesterone induces apoptosis of insulin-secreting cells: insights into the molecular mechanism.

S. Lenzen, A. K. Azevedo-Martins, L. Roma, 2014, The Journal of endocrinology.

Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.

M. Pandolfo, P. Marchetti, D. Eizirik, 2015, Human molecular genetics.

Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity

S. Lenzen, J. Saba, E. Gurgul-Convey, 2017, The Journal of Biological Chemistry.

Study of beta cells and neurons indicate incretin analogs as potential therapeutics for Friedreich’s ataxia. (S32.005)

M. Pandolfo, D. Eizirik, M. Igoillo-Esteve, 2015 .

MCPIP1 regulates the sensitivity of pancreatic beta-cells to cytokine toxicity

D. Eizirik, S. Lenzen, A. Jörns, 2019, Cell Death & Disease.

IL-1β hampers glucose-stimulated insulin secretion in Cohen diabetic rat islets through mitochondrial cytochrome c oxidase inhibition by nitric oxide.

Ann Saada, I. Raz, Genya Aharon-Hananel, 2014, American journal of physiology. Endocrinology and metabolism.

Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria

S. Lenzen, S. Lortz, I. Mehmeti, 2011, Journal of Molecular Medicine.

Relation between triketone structure, generation of reactive oxygen species, and selective toxicity of the diabetogenic agent alloxan.

S. Lenzen, M. Elsner, E. Gurgul-Convey, 2008, Antioxidants & redox signaling.

Protection of insulin-producing cells against toxicity of dexamethasone by catalase overexpression.

A. Boschero, E. Carneiro, S. Lenzen, 2009, Free Radical Biology & Medicine.

Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

O. Naujok, S. Lortz, E. Gurgul-Convey, 2013, Diabetologia.

MCPIP1 is a novel link between diabetogenic conditions and impaired insulin secretory capacity.

L. Marselli, M. Cnop, B. Tyrberg, 2021, Biochimica et biophysica acta. Molecular basis of disease.

The fate of intracellular S1P regulates lipid droplet turnover and lipotoxicity in pancreatic beta-cells

Yadi Tang, I. Mehmeti, E. Gurgul-Convey, 2024, Journal of lipid research.