B. Hang

发表

Cadmium(II) inhibition of human uracil-DNA glycosylase by catalytic water supplantation

T. Gokey, B. Hang, A. Guliaev, 2016, Scientific Reports.

HDL mimetic peptide ATI-5261 forms an oligomeric assembly in solution that dissociates to monomers upon dilution.

Greg L. Hura, V. Narayanaswami, Arti B. Patel, 2011, Biochemistry.

What structural features determine repair enzyme specificity and mechanism in chemically modified DNA?

B. Hang, B. Singer, 1997, Chemical research in toxicology.

NEIL2 Protects against Oxidative DNA Damage Induced by Sidestream Smoke in Human Cells

Sabrina Lin, I. Boldogh, T. Hazra, 2014, PloS one.

Synthesis of the Fully Protected Phosphoramidite of the Benzene-DNA Adduct, N 2-(4-Hydroxyphenyl)-2′-Deoxyguanosine and Incorporation of the Later into DNA Oligomers

F. Johnson, R. Bonala, B. Hang, 2008, Nucleosides, Nucleotides & Nucleic Acids.

Alkylpurine-DNA-N-glycosylase excision of 7-(hydroxymethyl)-1,N6-ethenoadenine, a glycidaldehyde-derived DNA adduct.

R. Elder, B. Hang, A. Guliaev, 2006, DNA repair.

Targeted deletion of alkylpurine-DNA-N-glycosylase in mice eliminates repair of 1,N6-ethenoadenine and hypoxanthine but not of 3,N4-ethenocytosine or 8-oxoguanine.

G. Margison, R. Elder, B. Hang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The p-benzoquinone DNA adducts derived from benzene are highly mutagenic.

Zhongwen Xie, Zhigang Wang, Huiyun Shen, 2005, DNA repair.

Nucleic acid sequence and repair: role of adduct, neighbor bases and enzyme specificity.

B. Hang, B. Singer, Bea Singer, 2000, Carcinogenesis.

Benzene-derived N2-(4-hydroxyphenyl)-deoxyguanosine adduct: UvrABC incision and its conformation in DNA.

B. Hang, A. Guliaev, A. Chenna, 2010, Toxicology letters.

8-(Hydroxymethyl)-3,N(4)-etheno-C, a potential carcinogenic glycidaldehyde product, miscodes in vitro using mammalian DNA polymerases.

Yanbin Zhang, Zhigang Wang, B. Hang, 2002, Biochemistry.

Thirdhand smoke causes DNA damage in human cells.

P. Jacob, H. Destaillats, L. Gundel, 2013, Mutagenesis.

Sequence-dependent repair of synthetic AP sites in 15-mer and 35-mer oligonucleotides: role of thermodynamic stability imposed by neighbor bases.

J. Sagi, B. Hang, B. Singer, 1999, Chemical research in toxicology.

Substrate specificity of human thymine-DNA glycosylase on exocyclic cytosine adducts.

B. Hang, A. Guliaev, 2007, Chemico-biological interactions.

Human Endonucleolytic Incision of DNA 3′ and 5′ to a Site-directed Psoralen Monoadduct and Interstrand Cross-link (*)

M. W. Lambert, B. Hang, K. Kumaresan, 1995, The Journal of Biological Chemistry.

Defective DNA endonuclease activities in Fanconi's anemia cells, complementation groups A and B.

W. Lambert, D. Parrish, G. Tsongalis, 1992, Mutation research.

Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p.

Hongbing Shen, Jingyan Dong, Zhibin Hu, 2013, Human reproduction.

Formation and Repair of Tobacco Carcinogen-Derived Bulky DNA Adducts

B. Hang, 2010, Journal of nucleic acids.

Increased risk of lung cancer associated with a functionally impaired polymorphic variant of the human DNA glycosylase NEIL2.

A. Tomkinson, Chen Wu, D. Lin, 2012, DNA repair.

Comprehensive pathway-based analysis identifies associations of BCL2, GNAO1 and CHD2 with non-obstructive azoospermia risk.

Zhibin Hu, Yankai Xia, J. Dai, 2014, Human reproduction.

Metal inhibition of human N-methylpurine-DNA glycosylase activity in base excision repair.

B. Hang, A. Guliaev, Ping Wang, 2006, Toxicology letters.

Metal inhibition of human alkylpurine-DNA-N-glycosylase activity in base excision repair

B. Hang, A. Guliaev, Ping Wang, 2006 .

Protein-protein interactions involving DNA glycosylases.

B. Singer, B. Hang, 2003, Chemical research in toxicology.

The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.

W. Bodell, B. Rydberg, E. Kim, 1995, Proceedings of the National Academy of Sciences of the United States of America.

A damage-recognition protein which binds to DNA containing interstrand cross-links is absent or defective in Fanconi anemia, complementation group A, cells.

M. W. Lambert, A. Yeung, B. Hang, 1993, Nucleic acids research.

An unusual mechanism for the major human apurinic/apyrimidinic (AP) endonuclease involving 5' cleavage of DNA containing a benzene-derived exocyclic adduct in the absence of an AP site.

H. Fraenkel-conrat, B. Hang, B. Singer, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Differential cleavage of oligonucleotides containing the benzene-derived adduct, 1,N6-benzetheno-dA, by the major human AP endonuclease HAP1 and Escherichia coli exonuclease III and endonuclease IV.

B. Hang, B. Singer, A. Chenna, 1998, Carcinogenesis.

A single cyclic p-benzoquinone adduct can destabilize a DNA oligonucleotide duplex.

J. Sagi, B. Hang, B. Singer, 1998, Chemical research in toxicology.

Evidence for a common active site for cleavage of an AP site and the benzene-derived exocyclic adduct, 3,N4-benzetheno-dC, in the major human AP endonuclease.

I. Hickson, D. Rothwell, J. Sagi, 1997, Biochemistry.

Early-life Tobacco Smoke/Nicotine Exposure and Offspring Health

V. Rehan, B. Hang, K. Kuniyoshi, 2020 .

Repair of exocyclic DNA adducts: rings of complexity

B. Hang, 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

Structural insights by molecular dynamics simulations into differential repair efficiency for ethano-A versus etheno-A adducts by the human alkylpurine-DNA N-glycosylase.

Anton B Guliaev, Bo Hang, B Singer, 2002, Nucleic acids research.

Correlation between Sequence-dependent Glycosylase Repair and the Thermal Stability of Oligonucleotide Duplexes Containing 1,N 6-Ethenoadenine*

J. Sagi, B. Hang, B. Singer, 1998, The Journal of Biological Chemistry.

Chloroethylnitrosourea-derived ethano cytosine and adenine adducts are substrates for Escherichia coli glycosylases excising analogous etheno adducts.

B. Hang, A. Guliaev, B. Singer, 2004, DNA repair.

A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch.

H. Fraenkel-conrat, B. Hang, B. Singer, 1998, Proceedings of the National Academy of Sciences of the United States of America.

1,N6-ethenoadenine and 3,N4-ethenocytosine are excised by separate human DNA glycosylases.

B. Hang, B. Singer, A. Chenna, 1996, Carcinogenesis.

Protein dynamics via computational microscope.

Anton B Guliaev, Senping Cheng, Bo Hang, 2012, World journal of methodology.

Structural insights by molecular dynamics simulations into specificity of the major human AP endonuclease toward the benzene-derived DNA adduct, pBQ-C.

B. Hang, A. Guliaev, B. Singer, 2004, Nucleic acids research.

Miscoding properties of 1,N6-ethanoadenine, a DNA adduct derived from reaction with the antitumor agent 1,3-bis(2-chloroethyl)-1-nitrosourea.

B. Hang, A. Guliaev, B. Singer, 2003, Mutation research.

Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

P. Freemont, I. Hickson, M. Gorman, 2000, Nucleic acids research.

Novel activity of Escherichia coli mismatch uracil-DNA glycosylase (Mug) excising 8-(hydroxymethyl)-3,N4-ethenocytosine, a potential product resulting from glycidaldehyde reaction.

B. Hang, A. Guliaev, B. Singer, 2002, Biochemistry.

Repair of exocyclic DNA adducts: rings of complexity

B. Hang, 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.