Y. Kapelyukh

发表

CYP2D6 substrates and drug metabolism

R. Wolf, Y. Kapelyukh, 2014 .

The usage of a three-compartment model to investigate the metabolic differences between hepatic reductase null and wild-type mice.

M. Chaplain, R. Wolf, L. Hill, 2015, Mathematical medicine and biology : a journal of the IMA.

DMD055277 70..77

R. Finn, C. Wolf, Sébastien Ronseaux, 2013 .

Improving the predictive power of xenograft and syngeneic anti-tumour studies using mice humanised for pathways of drug metabolism

C. Wolf, C. Henderson, A. McLaren, 2022, F1000Research.

Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model

C. Wolf, D. Busch, S. Oswald, 2015, Drug Metabolism and Disposition.

Microsoft Word-64262667-file00

D. Busch, S. Oswald, N. Scheer, 2015 .

Quantitative Prediction of Human Pregnane X Receptor and Cytochrome P450 3A4 Mediated Drug-Drug Interaction in a Novel Multiple Humanized Mouse Line

C. Wolf, J. Seibler, N. Scheer, 2011, Molecular Pharmacology.

cluster knockout and CYP2C9 humanized mouse lines

N. Scheer, R. Wolf, L. Chatham, 2012 .

Mathematical modeling quantifies ERKactivity in response to inhibition of the BRAFV600EMEKERK cascade

Mark A. J. Chaplain, M. Chaplain, C. Wolf, 2021 .

Quantifying ERK activity in response to inhibition of the BRAFV600E-MEK-ERK cascade using mathematical modelling

Mark A. J. Chaplain, M. Chaplain, C. Henderson, 2021, British Journal of Cancer.

Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines

C. Wolf, N. Scheer, L. Chatham, 2012, Molecular Pharmacology.

Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

C. Wolf, L. Stanley, N. Scheer, 2012, Molecular Pharmacology.

In Vivo Responses of the Human and Murine Pregnane X Receptor to Dexamethasone in Mice

C. Wolf, N. Scheer, Y. Kapelyukh, 2010, Drug Metabolism and Disposition.

In vivo responses of the human and murine pregnane X receptor to dexamethasone in mice

N. Scheer, Y. Kapelyukh, A. Rode, 2010 .

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice

C. Wolf, N. Scheer, C. Henderson, 2019, Drug Metabolism and Disposition.

A Role for Cytochrome b5 in the In Vivo Disposition of Anticancer and Cytochrome P450 Probe Drugs in Mice

R. Finn, C. Wolf, Sébastien Ronseaux, 2014, Drug Metabolism and Disposition.

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

C. Wolf, L. Stanley, N. Scheer, 2019, Drug Metabolism and Disposition.

University of Dundee An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug / Drug Interactions , and to Facilitate Design of Clinical Trials

C. Wolf, L. Stanley, N. Scheer, 2019 .

A Role for Cytochrome b 5 in the In Vivo Disposition of Anticancer and Cytochrome P 450 Probe Drugs in Mice s

R. Finn, C. Wolf, Sébastien Ronseaux, 2013 .

Multiple Substrate Binding by Cytochrome P450 3A4: Estimation of the Number of Bound Substrate Molecules

M. Sutcliffe, Jean‐Didier Maréchal, C. Wolf, 2008, Drug Metabolism and Disposition.

Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines

N. Scheer, L. Chatham, Y. Kapelyukh, 2012, Molecular Pharmacology.

Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines

L. Stanley, N. Scheer, Jillian McEwan, 2012, Molecular Pharmacology.

Simulating BRAFV600E-MEK-ERK signalling dynamics in response to vertical inhibition treatment strategies

Mark A. J. Chaplain, J. Kursawe, Y. Kapelyukh, 2024, bioRxiv.