T. Honda

CYP2D6-Mediated Metabolism of a Novel Acyl Coenzyme A:Cholesterol Acyltransferase Inhibitor, Pactimibe, and Its Unique Plasma Metabolite, R-125528

H. Saji, M. Kotsuma, H. Iwabuchi, 2008, Drug Metabolism and Disposition.

Datopotamab Deruxtecan, a Novel TROP2-directed Antibody–drug Conjugate, Demonstrates Potent Antitumor Activity by Efficient Drug Delivery to Tumor Cells

M. Yamaguchi, M. Murakami, H. Hamada, 2021, Molecular Cancer Therapeutics.

Structure Elucidation of Novel Metabolites of Gemfibrozil in Dog : Conjugation Reaction of Conjugated Metabolites

H. Yoshii, M. Ishikawa, H. Iwabuchi, 2004 .

Species differences between rats and primates (humans and monkeys) in complex cleavage pathways of DS-8500a characterized by 14C-ADME studies in humans and monkeys after administration of two radiolabeled compounds and in vitro studies.

Manabu Kato, H. Takakusa, D. Nakai, 2022, Drug metabolism and pharmacokinetics.

Bioactivation of loxoprofen to a pharmacologically active metabolite and its disposition kinetics in human skin

A. Shinagawa, Naoya Wada, T. Izumi, 2015, Biopharmaceutics & drug disposition.

10P DS-6000a, a novel CDH6-targeting antibody-drug conjugate with a novel DNA topoisomerase I inhibitor DXd, demonstrates potent antitumor activity in preclinical models

T. Agatsuma, H. Suzuki, T. Nakada, 2021, Annals of Oncology.

A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro.

Y. Sugiyama, Kiyomi Ito, W. Takasaki, 2001, Drug metabolism and disposition: the biological fate of chemicals.

A comparison of the effects of 3-hydroxy-3-methylglutaryl-coenzyme a (HMG-CoA) reductase inhibitors on the CYP3A4-dependent oxidation of mexazolam in vitro.

Y. Sugiyama, Kiyomi Ito, W. Takasaki, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Pharmacokinetics of DS-5565, a novel α2δ ligand, in rats and monkeys and assessment of DDI risk

T. Honda, Hiroko Koda, Y. Domon, 2013, Journal of the Neurological Sciences.