Sylwia Stachura

发表

Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists.

Michael A. Galella, D. Shen, C. Weigelt, 2020, Bioorganic & medicinal chemistry letters.

Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.

P. Sleph, L. Abell, D. Gordon, 2017 .

Discovery of a JAK1/3 Inhibitor and Use of a Prodrug To Demonstrate Efficacy in a Model of Rheumatoid Arthritis.

Michael A. Galella, S. Spergel, K. McIntyre, 2019, ACS medicinal chemistry letters.

Discovery and SAR of pyrrolo[2,1-f][1,2,4]triazin-4-amines as potent and selective PI3Kδ inhibitors.

C. Weigelt, M. Poss, J. Sack, 2016, Bioorganic & medicinal chemistry letters.

Triazolopyrimidines identified as reversible myeloperoxidase inhibitors.

P. Sleph, L. Abell, D. Gordon, 2017, MedChemComm.

Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists.

Michael A. Galella, D. Shuster, D. Shen, 2019, ACS medicinal chemistry letters.

Discovery of potent and efficacious pyrrolopyridazines as dual JAK1/3 inhibitors.

K. McIntyre, Sidney Pitt, G. Schieven, 2017, Bioorganic & medicinal chemistry letters.

Substituted Diaryl Ether Compounds as Retinoic Acid-Related Orphan Receptor-γt (RORγt) Agonists.

Zhuyin Li, C. Weigelt, B. Fink, 2021, Bioorganic & medicinal chemistry letters.

Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists.

Zhuyin Li, C. Weigelt, B. Fink, 2020, Bioorganic & medicinal chemistry letters.

Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity.

Michael A. Galella, D. Shen, J. Barrish, 2018, Bioorganic & medicinal chemistry letters.

Discovery of Potent and Selective Quinoxaline-Based Protease-Activated Receptor 4 (PAR4) Antagonists for the Prevention of Arterial Thrombosis.

Shana L. Posy, R. Wexler, J. M. Richter, 2024, Journal of medicinal chemistry.

Substituted benzyloxytricyclic compounds as retinoic acid-related orphan receptor gamma t (RORγt) agonists.

C. Weigelt, B. Fink, T. Huynh, 2020, Bioorganic & medicinal chemistry letters.