B. Geddes

发表

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice

P. Distefano, K. Longo, Yong Qi, 2008, Regulatory Peptides.

Pharmacologic Inhibition of Ghrelin Receptor Signaling Is Insulin Sparing and Promotes Insulin Sensitivity

P. Distefano, M. Navia, J. Hixon, 2011, Journal of Pharmacology and Experimental Therapeutics.

Characterization of the insulin sensitivity of ghrelin receptor KO mice using glycemic clamps

P. Distefano, J. Hixon, J. Saunders, 2011, BMC Physiology.

Brain angiotensin-II partially mediates the effects of relaxin on vasopressin and oxytocin release in anesthetized rats.

L. Parry, A. Summerlee, B. Geddes, 1994, Endocrinology.

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.

Michelle C. Schaeffer, Carol A. Capriotti, Paul E. Lamoureux, 2019, Journal of medicinal chemistry.

Enhanced Gastrointestinal Motility with Orally Active Ghrelin Receptor Agonists

P. Distefano, J. Hixon, K. Longo, 2009, Journal of Pharmacology and Experimental Therapeutics.

The Emerging Concept of Relaxn as a Centrally Actng Peptide Hormone with Hemodynamic Actions

A. Summerlee, B. Geddes, 1995, Journal of neuroendocrinology.

CARD-8 Protein, a New CARD Family Member That Regulates Caspase-1 Activation and Apoptosis*

J. Bertin, P. Distefano, S. Srinivasula, 2002, The Journal of Biological Chemistry.

Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: suppression of the immune response with cyclosporin.

S. Lightman, J. Uney, S. Lightman, 1996, Endocrinology.

Stage-Dependent Impact of RIPK1 Inhibition on Atherogenesis: Dual Effects on Inflammation and Foam Cell Dynamics

J. Bertin, Michael A. Reilly, Yonghu Huang, 2021, Frontiers in Cardiovascular Medicine.

Insulin resistance, glycemic control and adiposity: key determinants of healthy lifespan.

P. Distefano, R. Curtis, B. Geddes, 2007, Current Alzheimer research.

The prolactin-releasing peptide receptor (GPR10) regulates body weight homeostasis in mice

K. Foley, W. Gu, C. Zhang, 2007, Journal of Molecular Neuroscience.

Central Effects of Long‐Term Relaxin Expression in the Rat

A. Summerlee, J. Silvertown, B. Geddes, 2005, Annals of the New York Academy of Sciences.

Insulin-like growth factor 2 (IGF2) protects against Huntington’s disease through the extracellular disposal of protein aggregates

L. Ellerby, C. Hetz, K. Longo, 2020, bioRxiv.

Insulin-like growth factor 2 (IGF2) protects against HD through the extracellular disposal of protein aggregates

C. Hetz, K. Longo, F. Court, 2019 .

An Intestinal Organoid-Based Platform That Recreates Susceptibility to T Cell-Mediated Tissue Injury.

J. Bertin, P. Loke, M. V. D. van den Brink, 2020, Blood.

Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system

J. Uney, T. Harding, D. Murphy, 1998, Nature Biotechnology.

Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance

J. Bertin, J. Choudhary, Lu Yu, 2021, Nature Communications.

The 24-hour respiratory quotient predicts energy intake and changes in body mass.

P. Distefano, K. Longo, T. McDonagh, 2010, American journal of physiology. Regulatory, integrative and comparative physiology.

PYPAF7, a Novel PYRIN-containing Apaf1-like Protein That Regulates Activation of NF-κB and Caspase-1-dependent Cytokine Processing*

J. Bertin, P. Distefano, Jill M. Grenier, 2002, The Journal of Biological Chemistry.

PYPAF1, a PYRIN-containing Apaf1-like Protein That Assembles with ASC and Regulates Activation of NF-κB*

J. Bertin, P. Distefano, J. Lora, 2002, The Journal of Biological Chemistry.

Assessing Viral Gene Therapy in Neuroendocrine Models

S. Lightman, J. Uney, T. Harding, 1999, Frontiers in Neuroendocrinology.

Adenovirus-mediated expression of human prorelaxin promotes the invasive potential of canine mammary cancer cells.

A. Summerlee, J. Silvertown, B. Geddes, 2003, Endocrinology.

Long-term gene therapy in the CNS: Reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin

S. Lightman, J. Uney, T. Harding, 1997, Nature Medicine.

Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis.

J. Bertin, P. Distefano, W. Huang, 2001, Biochemical and biophysical research communications.

Daily energy balance in growth hormone receptor/binding protein (GHR -/-) gene-disrupted mice is achieved through an increase in dark-phase energy efficiency.

P. Distefano, K. Longo, J. Kopchick, 2010, Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

RIPK1 kinase-dependent inflammation and cell death contribute to the pathogenesis of COPD

M. Bertrand, J. Bertin, T. Vanden Berghe, 2022, European Respiratory Journal.

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Brad Geddes, B. Geddes, 2010 .

Reply to Guo and Hall

K. Longo, B. Geddes, 2011 .

Enhanced Gastrointestinal Motility with Orally Active Ghrelin Receptor Agonists

P. Distefano, J. Hixon, K. Longo, 2009, Journal of Pharmacology and Experimental Therapeutics.