A. Sharp

发表

Correlation of in vitro MIC and MFC against isavuconazole, voriconazole, and amphotericin B of Aspergillus with in vivo outcome in mice with disseminated Aspergillosis

D. Denning, J. Majithiya, P. Warn, 2008 .

Effect of hypoxic conditions on in vitro susceptibility testing of amphotericin B, itraconazole and micafungin against Aspergillus and Candida.

D. Denning, J. Guinea, P. Warn, 2004, The Journal of antimicrobial chemotherapy.

Impact of Bolus Dosing versus Continuous Infusion of Piperacillin and Tazobactam on the Development of Antimicrobial Resistance in Pseudomonas aeruginosa

M. Neely, S. Howard, J. Goodwin, 2013, Antimicrobial Agents and Chemotherapy.

Streptococcus pneumoniae worsens cerebral ischemia via interleukin 1 and platelet glycoprotein Ibα

N. Rothwell, B. Nieswandt, S. Allan, 2014, Annals of neurology.

Disseminated Candidiasis Caused by Candida albicans with Amino Acid Substitutions in Fks1 at Position Ser645 Cannot Be Successfully Treated with Micafungin

M. Arendrup, P. Warn, D. Perlin, 2011, Antimicrobial Agents and Chemotherapy.

Intermittent micafungin for prophylaxis in a rat model of chronic Candida albicans gut colonization.

A. Sattar, N. Undre, P. Warn, 2020, The Journal of antimicrobial chemotherapy.

Anidulafungin for Neonatal Hematogenous Candida Meningoencephalitis: Identification of Candidate Regimens for Humans Using a Translational Pharmacological Approach

D. Benjamin, M. Cohen-Wolkowiez, T. Walsh, 2011, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Pharmacodynamics of a Novel Triazole, Isavuconazole: Mathematical Modeling, Importance of Tissue Concentrations, and Impact of Immune Status on Antifungal Effect

D. Denning, P. Warn, J. Majithiya, 2009, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Pharmacodynamics of a Novel Triazole, Isavuconazole: Mathematical Modeling, Importance of Tissue Concentrations, and Impact of Immune Status on Antifungal Effect (cid:1)

D. Denning, P. Warn, J. Majithiya, 2009 .

Effect of Neutropenia and Treatment Delay on the Response to Antifungal Agents in Experimental Disseminated Candidiasis

D. Denning, G. Drusano, T. Walsh, 2006, Antimicrobial Agents and Chemotherapy.

The novel fungal CYP51 inhibitor VT-1598 displays classic dose-dependent antifungal activity in murine models of invasive aspergillosis.

E. Garvey, C. M. Yates, M. Atari, 2020, Medical mycology.

Peroral Amphotericin B Polymer Nanoparticles Lead to Comparable or Superior In Vivo Antifungal Activity to That of Intravenous Ambisome® or Fungizone™

P. Warn, M. R. Kumar, J. Italia, 2011, PloS one.

Pharmacokinetics and pharmacodynamics of posaconazole for invasive pulmonary aspergillosis: clinical implications for antifungal therapy.

P. Warn, J. Majithiya, S. Howard, 2011, The Journal of infectious diseases.

Derivation of an In Vivo Drug Exposure Breakpoint for Flucytosine against Candida albicans and Impact of the MIC, Growth Rate, and Resistance Genotype on the Antifungal Effect

David W. Denning, Miki Kasai, Thomas J. Walsh, 2006, Antimicrobial Agents and Chemotherapy.

In vivo activity of micafungin in a persistently neutropenic murine model of disseminated infection caused by Candida tropicalis.

D. Denning, P. Warn, A. Sharp, 2002, The Journal of antimicrobial chemotherapy.

Pharmacokinetics and Pharmacodynamics of Anidulafungin for Experimental Candida Endophthalmitis: Insights into the Utility of Echinocandins for Treatment of a Potentially Sight-Threatening Infection

P. Warn, S. Howard, J. Goodwin, 2012, Antimicrobial Agents and Chemotherapy.

In vitro activity of a new triazole BAL4815, the active component of BAL8557 (the water-soluble prodrug), against Aspergillus spp.

D. Denning, P. Warn, A. Sharp, 2006, The Journal of antimicrobial chemotherapy.

Pharmacokinetics and Pharmacodynamics of Fluconazole for Cryptococcal Meningoencephalitis: Implications for Antifungal Therapy and In Vitro Susceptibility Breakpoints

J. Perfect, T. Harrison, P. Warn, 2013, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics and Pharmacodynamics of Fluconazole For

J. Perfect, T. Harrison, P. Warn, 2013 .

The novel fungal CYP51 inhibitor VT-1598 is efficacious alone and in combination with liposomal amphotericin B in a murine model of cryptococcal meningitis

E. Garvey, C. M. Yates, R. Schotzinger, 2018, The Journal of antimicrobial chemotherapy.

P1951 Dose response in neutropenic mice with disseminated infec-tion of multiple strains of Aspergillus fumigatus with widely varying MIC and MFC values treated with isavuconazole

D. Denning, P. Warn, A. Parmar, 2007 .

Comparative in vivo activity of BAL4815, the active component of the prodrug BAL8557, in a neutropenic murine model of disseminated Aspergillus flavus.

D. Denning, P. Warn, A. Schmitt-Hoffmann, 2006, The Journal of antimicrobial chemotherapy.

Efficacy of an Abbreviated Induction Regimen of Amphotericin B Deoxycholate for Cryptococcal Meningoencephalitis: 3 Days of Therapy Is Equivalent to 14 Days

J. Perfect, Werner Müller, T. Harrison, 2014, mBio.

Activity of aminocandin (IP960) compared with amphotericin B and fluconazole in a neutropenic murine model of disseminated infection caused by a fluconazole-resistant strain of Candida tropicalis.

D. Denning, P. Warn, A. Sharp, 2005, The Journal of antimicrobial chemotherapy.

The efficacy of aerosol treatment with non-ionic surfactant vesicles containing amphotericin B in rodent models of leishmaniasis and pulmonary aspergillosis infection.

G. H. Coombs, A. Thomson, P. Warn, 2012, Journal of controlled release : official journal of the Controlled Release Society.

Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients.

J. Perfect, M. Neely, T. Harrison, 2013, The Journal of infectious diseases.

Activity of aminocandin (IP960; HMR3270) compared with amphotericin B, itraconazole, caspofungin and micafungin in neutropenic murine models of disseminated infection caused by itraconazole-susceptible and -resistant strains of Aspergillus fumigatus.

D. Denning, P. Warn, A. Sharp, 2010, International journal of antimicrobial agents.

ctivity of aminocandin (IP960; HMR3270) compared with amphotericin B, traconazole, caspofungin and micafungin in neutropenic murine models of isseminated infection caused by itraconazole-susceptible and -resistant strains f Aspergillus fumigatus

D. Denning, A. Warn, A. Sharp, 2009 .

Efficacy of isavuconazole, voriconazole and fluconazole in temporarily neutropenic murine models of disseminated Candida tropicalis and Candida krusei.

D. Denning, P. Warn, J. Majithiya, 2008, The Journal of antimicrobial chemotherapy.

Surface response modeling to examine the combination of amphotericin B deoxycholate and 5-fluorocytosine for treatment of invasive candidiasis.

B. Keevil, D. Denning, G. Drusano, 2005, The Journal of infectious diseases.

In vitro interaction of terbinafine with itraconazole, fluconazole, amphotericin B and 5-flucytosine against Aspergillus spp.

C B Moore, P. Warn, C. Moore, 2002, The Journal of antimicrobial chemotherapy.

Infrared body temperature measurement of mice as an early predictor of death in experimental fungal infections

P. Warn, D. Denning, N. Steel, 2003, Laboratory animals.

In Vitro Activity of the Echinocandin HMR3270 against Aspergillus spp.

D. Denning, P. Warn, A. Sharp, 2001 .

Pharmacodynamics of Echinocandins against Candida glabrata: Requirement for Dosage Escalation To Achieve Maximal Antifungal Activity in Neutropenic Hosts

P. Warn, D. Perlin, A. Alastruey‐Izquierdo, 2011, Antimicrobial Agents and Chemotherapy.

Optimization of the Dosage of Flucytosine in Combination with Amphotericin B for Disseminated Candidiasis: a Pharmacodynamic Rationale for Reduced Dosing

B. Keevil, D. Denning, G. Drusano, 2007, Antimicrobial Agents and Chemotherapy.

Infection Augments Expression of Mechanosensing Piezo1 Channels in Amyloid Plaque-Reactive Astrocytes

E. Moeendarbary, K. Dev, H. Boutin, 2018, Front. Aging Neurosci..

Single-spore cultures of the sequences strain of Aspergillus fumigatus (Af293) have significantly different mortality rates in a murine model of IPA

D. Denning, M. Anderson, P. Warn, 2006 .

Efficacy of Isavuconazole, voriconazole and. fluconazole in a neutropenic mice murine model of Candida krusei

J. Majithiya, D. Denning, P. Warn, 2009 .