R. Frum

发表

MDM2 Controls the Timely Expression of Cyclin A to Regulate the Cell Cycle

S. Deb, S. Deb, M. Ramamoorthy, 2009, Molecular Cancer Research.

Temporal differences in DNA replication during the S phase using single fiber analysis of normal human fibroblasts and glioblastoma T98G cells

D. Kaufman, Z. Khondker, R. Frum, 2009, Cell cycle.

DNA replication in early S phase pauses near newly activated origins

D. Kaufman, Pingping Qu, Stephanie M. Cohen, 2008, Cell cycle.

Flow cytometric analysis of MDM2-mediated growth arrest.

S. Deb, R. Frum, 2003, Methods in molecular biology.

Use of the DNA fiber spreading technique to detect the effects of mutant p53 on DNA replication.

S. Deb, S. Deb, R. Frum, 2013, Methods in molecular biology.

The growth arrest function of the human oncoprotein mouse double minute-2 is disabled by downstream mutation in cancer cells.

S. Deb, S. Deb, R. Frum, 2005, Cancer research.

The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing

N. Mukhopadhyay, S. Grossman, S. Deb, 2013, Nucleic acids research.

HDM2-binding partners: interaction with translation elongation factor EF1alpha.

Scott A. Busby, Scott A Busby, J. Shabanowitz, 2007, Journal of proteome research.

Role of MDM2 In Cell Growth Regulation

R. Frum, 2006 .

The Role of the Nucleolus in the Stress Response

Yanping Zhang, L. Tollini, R. Frum, 2011 .

Mechanisms of mutant p53 stabilization in cancer.

S. Grossman, R. Frum, 2014, Sub-cellular biochemistry.

Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication

S. Grossman, S. Deb, Shilpa Singh, 2017, The Journal of clinical investigation.

Transactivation and transrepression studies with p53.

M. Scian, S. Deb, S. Deb, 2003, Methods in molecular biology.

Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl.

S. Grossman, S. Deb, S. Deb, 2012, Genes & cancer.

Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination

N. Mukhopadhyay, S. Grossman, S. Deb, 2016, Molecular Cancer Research.

The human oncoprotein MDM2 uses distinct strategies to inhibit transcriptional activation mediated by the wild-type p53 and its tumor-derived mutants.

S. Deb, S. Deb, R. Muñoz, 2001, International journal of oncology.

Allele specific gain-of-function activity of p53 mutants in lung cancer cells.

S. Deb, S. Deb, Shilpa Singh, 2012, Biochemical and biophysical research communications.