A. Frede

Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells

R. D'Andrea, A. Somogyi, D. White, 2012, British Journal of Cancer.

Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib.

P. Manley, D. White, T. Hughes, 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Chronic Myeloid Leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 Activity

A. Zannettino, A. Zannettino, D. White, 2010, Leukemia.

Dasatinib Cellular Uptake and Efflux in Chronic Myeloid Leukemia Cells: Therapeutic Implications

J. Melo, L. To, Sharad Kumar, 2008, Clinical Cancer Research.

Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors

J. Melo, R. D'Andrea, Angel F. Lopez, 2010, Leukemia.

The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells.

A. Zannettino, D. White, T. Hughes, 2010, Blood.

Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to high-dose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinib

J. Radich, G. Martinelli, P. Manley, 2012, Haematologica.

CML Patients with Low OCT-1 Activity Achieve Better Molecular Responses on High Dose Imatinib Than on Standard Dose. Those with High OCT-1 Activity Have Excellent Responses on Either Dose: A TOPS Correlative Study

J. Radich, M. Thornquist, G. Martinelli, 2008 .

The Functional Activity of the OCT-1 Protein Is Predictive of Molecular Response and Survival in CP-CML Patients Treated with Imatinib: A 5 Year Update of the TIDEL Trial.

P. Manley, D. White, T. Hughes, 2009 .

Reduced Activity of the OCT-1 Protein in Primitive CML Cells: A Likely Determinant of Stem Cell Resistance in Imatinib Treated CML Patients

A. Zannettino, D. White, T. Hughes, 2008 .

Enhancing the Functional Activity of the OCT-1 Influx Pump May Overcome the Negative Impact of Low OCT-1 Activity in Imatinib Treated CML Patients

D. White, C. Kok, P. Dang, 2008 .