J. Rayner

Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity.

S. Boyer, C. Donald, A. Turnbull, 2002, Journal of medicinal chemistry.

Discovery, synthesis and biological evaluation of novel glucokinase activators.

Scott Boyd, G. Currie, B. Hayter, 2005, Bioorganic & medicinal chemistry letters.

Design of a potent, soluble glucokinase activator with increased pharmacokinetic half-life.

D. Mckerrecher, C. Johnstone, Craig S Donald, 2011, Bioorganic & medicinal chemistry letters.

Property based optimisation of glucokinase activators – discovery of the phase IIb clinical candidate AZD1656

Michael J. Waring, Graeme R. Robb, David S. Clarke, 2012 .

Design of a potent, soluble glucokinase activator with excellent in vivo efficacy.

D. Mckerrecher, C. Johnstone, Keith M Johnson, 2006, Bioorganic & medicinal chemistry letters.