M. Hammond

发表

In vitro and in vivo characterization of 3-[2-[6-(2-tert-butoxyethoxy)pyridin-3-yl]-1H-imidazol-4-yl]benzonitrile hydrochloride salt, a potent and selective NPY5 receptor antagonist.

T. Maurer, D. Hargrove, C. Mack, 2003, Journal of medicinal chemistry.

Structure-activity relationship studies on 2-heteroaryl-4-arylimidazoles NPY5 receptor antagonists.

T. Maurer, C. Mack, Robert M. Oliver, 2003, Bioorganic & medicinal chemistry letters.

2,3-Dihydro-5-benzofuranols as antioxidant-based inhibitors of leukotriene biosynthesis.

F. Baker, D. Macintyre, J. Boger, 1989, Journal of medicinal chemistry.

Biochemical and biological activities of 2,3-dihydro-6-[3-(2-hydroxymethyl)phenyl-2-propenyl]-5-benzofuranol (L-651,896), a novel topical anti-inflammatory agent.

R. Egan, E. Opas, N. Jensen, 1987, Biochemical pharmacology.

A Concise Synthesis of the Naphthoic Acid Component of Neocarzinostatin Chromophore Featuring a New Photocyclization Reaction

V. Subramanian, A. Myers, M. Hammond, 1996 .

Design and synthesis of orally bioavailable serum and glucocorticoid-regulated kinase 1 (SGK1) inhibitors.

Baoguang Zhao, M. Head, N. Laping, 2009, Bioorganic & medicinal chemistry letters.

Synthetic replacement of the methylamino group of neocarzinostatin chromophore with hydroxyl prohibits thiol activation in organic solvents and diminishes the rate and efficiency of thiol-promoted DNA cleavage in water

A. Myers, Jun Liang, M. Hammond, 1999 .

Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K).

D. Holt, A. P. Graves, L. Shewchuk, 2015, Journal of medicinal chemistry.

Identi fi cation of Purines and 7 ‐ Deazapurines as Potent and Selective Type I Inhibitors of Troponin I ‐ Interacting Kinase ( TNNI 3 K )

D. Holt, A. P. Graves, L. Shewchuk, 2015 .

2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.

C. Duraiswami, Yonghui Wang, T. Graybill, 2009, Bioorganic & medicinal chemistry letters.

Development of an enantioselective synthetic route to neocarzinostatin chromophore and its use for multiple radioisotopic incorporation.

S. Schaus, Yusheng Wu, A. Myers, 2002, Journal of the American Chemical Society.

ENANTIOSELECTIVE SYNTHESIS OF NEOCARZINOSTATIN CHROMOPHORE AGLYCON

Yusheng Wu, A. Myers, P. M. Harrington, 1996 .

Directed regiochemical control in the ring expansion reactions of a substituted trans-decalone

J. Aubé, M. Hammond, 1990 .

Synthetic aspects of an asymmetric nitrogen-insertion process: preparation of chiral, non-racemic caprolactams and valerolactams. Total synthesis of (-)-alloyohimbane

J. Aubé, F. Takusagawa, Y. Wang, 1990 .

An Improved Preparation of Highly Enantiomerically Enriched (R)-(+)-4-tert-Butyldimethylsiloxy-2-cyclopenten-1-one.

Yusheng Wu, A. Myers, M. Hammond, 1996 .

A mild, osmium tetraoxide-catalyzed method for the oxidation of sulfides to sulfones

S. Kaldor, M. Hammond, 1991 .

Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

N. Laping, D. Kazmin, S. Thompson, 2008, Cancer research.

Syntheses and analgesic/antiinflammatory activities of novel 2-|5-aroyl pyrrolo|alkanoic acids

R. Zambias, M. Goldenberg, P. Bailey, 1987 .

A Comparison of DNA Cleavage by Neocarzinostatin Chromophore and Its Aglycon: Evaluating the Role of the Carbohydrate Residue

M. Kort, A. Myers, M. Hammond, 1997 .

TOTAL SYNTHESIS OF (+)-NEOCARZINOSTATIN CHROMOPHORE

Yusheng Wu, A. Myers, Jun Liang, 1998 .

Syntheses and Rearrangements of Spirocyclic Oxaziridines Derived from Unsymmetrical Ketones.

J. Aubé, F. Takusagawa, M. Hammond, 1991 .

Syntheses and rearrangements of spirocyclic oxaziridines derived from unsymmetrical ketones

J. Aubé, F. Takusagawa, M. Hammond, 1991 .

Bioisosteric replacement of the hydrazide pharmacophore of the cannabinoid-1 receptor antagonist SR141716A. Part I: potent, orally-active 1,4-disubstituted imidazoles.

D. Scott, P. Iredale, R. L. Dow, 2009, Bioorganic & medicinal chemistry letters.

Structure-activity relationships in a series of NPY Y5 antagonists: 3-amido-9-ethylcarbazoles, core-modified analogues and amide isosteres.

C. Mack, Robert M. Oliver, R. Hank, 2003, Bioorganic & medicinal chemistry letters.

ITERATIVE PROTEIN STRUCTURE-BASED DRUG DESIGN AND SYNTHESIS OF HIV PROTEASE INHIBITORS

K. Appelt, V. Kalish, J. Davies, 1995, European Journal of Medicinal Chemistry.

Discovery of GSK2798745: A Clinical Candidate for Inhibition of Transient Receptor Potential Vanilloid 4 (TRPV4).

Carl A. Brooks, D. Holt, D. Behm, 2019, ACS medicinal chemistry letters.

Improving the developability profile of pyrrolidine progesterone receptor partial agonists.

C. Duraiswami, N. Laping, Shawn P. Williams, 2010, Bioorganic & medicinal chemistry letters.

Reverse Hydroxamate Inhibitors of Bone Morphogenetic Protein 1.

R. A. Reid, D. Holt, R. Gampe, 2018, ACS medicinal chemistry letters.

A systematic study of P1–P3 spanning sidechains for the inhibition of HIV-1 protease

K. Appelt, M. Muesing, S. Kaldor, 1995 .