K. Nonoshita

发表

Design and synthesis of the potent, orally available, brain-penetrable arylpyrazole class of neuropeptide Y5 receptor antagonists.

M. Hirose, N. Fujino, A. Kanatani, 2003, Journal of medicinal chemistry.

Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators.

M. Ishikawa, Y. Ogino, T. Nishimura, 2009, Bioorganic & medicinal chemistry letters.

Efficient and stereoselective synthesis of J-104,118, a novel, potent inhibitor of squalene synthase

Y. Iwasawa, K. Tomimoto, K. Nonoshita, 1995 .

Discovery of trans-N-[1-(2-fluorophenyl)-3-pyrazolyl]-3-oxospiro[6-azaisobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide, a potent and orally active neuropeptide Y Y5 receptor antagonist.

H. Iwaasa, M. Ando, M. Ishikawa, 2009, Bioorganic & medicinal chemistry.

Identification of positron emission tomography ligands for NPY Y5 receptors in the brain.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Unusual conjugate addition of organolithium reagent to α, β-unsaturated ketone

K. Maruoka, Hisashi Yamamoto, K. Nonoshita, 1987 .

Conjugate Reduction of α,β-Unsaturated Ketones with Amphiphilic Reaction System

K. Maruoka, Hisashi Yamamoto, K. Nonoshita, 1988 .

Amphiphilic reactions by means of exceptionally bulky organoaluminum reagents. Rational approach for obtaining unusual equatorial, anti-Cram, and 1,4 selectivity in carbonyl alkylation

M. Sakurai, K. Maruoka, Hisashi Yamamoto, 1988 .

(9S)-9-(2-hydroxy-4,4-dimethyl-6-oxo-1-cyclohexen-1-yl)-3,3-dimethyl-2,3,4,9-tetrahydro-1H-xanthen-1-one, a selective and orally active neuropeptide Y Y5 receptor antagonist.

H. Iwaasa, M. Ando, T. Ohe, 2008, Journal of medicinal chemistry.

Organoaluminum-promoted Claisen rearrangement of allyl vinyl ethers

K. Maruoka, H. Banno, Hisashi Yamamoto, 1990 .

Stereoselective C-Glycosidation of Glycals with Organoaluminum Reagents

K. Maruoka, Hisashi Yamamoto, T. Itoh, 1987 .

Unprecedented stereochemical control in the Claisen rearrangement of allyl vinyl ethers using organoaluminum reagents

K. Maruoka, H. Banno, Hisashi Yamamoto, 1988 .

Organoaluminum-promoted Claisen rearrangement of bisallyl vinyl ethers

K. Maruoka, H. Banno, Hisashi Yamamoto, 1989 .

Electronic and Steric Effects of Lewis Acidic Organoaluminum Reagents in the Diels-Alder Reaction

K. Maruoka, Hisashi Yamamoto, K. Nonoshita, 1988 .

Amphiphilic Reactions by Means of Exceptionally Bulky Organoaluminum Reagents. Rational Approach for Obtaining Unusual Equatorial, Anti‐Cram, and 1,4 Selectivity in Carbonyl Alkylation.

M. Sakurai, K. Maruoka, Hisashi Yamamoto, 1988 .

Unusual Conjugate Addition of Organolithium Reagent to α,β-Unsaturated Ketone.

K. Maruoka, Hisashi Yamamoto, K. Nonoshita, 1988 .

TAS-121, A Selective Mutant EGFR Inhibitor, Shows Activity Against Tumors Expressing Various EGFR Mutations Including T790M and Uncommon Mutations G719X

Masanori Kato, Y. Ohe, Kimihiro Ito, 2019, Molecular Cancer Therapeutics.

On the mechanism of organoaluminum-promoted claisen rearrangement of allylic vinyl ethers

K. Maruoka, Hisashi Yamamoto, K. Nonoshita, 1992 .

Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists.

D. Macneil, H. Iwaasa, A. Kanatani, 2009, Bioorganic & Medicinal Chemistry Letters.

Novel orally active NPY Y5 receptor antagonists: Synthesis and structure-activity relationship of spiroindoline class compounds.

H. Iwaasa, A. Kanatani, T. Fukami, 2009, Bioorganic & medicinal chemistry.

Novel potent neuropeptide Y Y5 receptor antagonists: synthesis and structure-activity relationships of phenylpiperazine derivatives.

H. Iwaasa, M. Hirose, A. Kanatani, 2006, Bioorganic & medicinal chemistry.

A new class of highly potent farnesyl diphosphate-competitive inhibitors of farnesyltransferase.

T. Kodera, Y. Iwasawa, J. Shibata, 1998, Journal of medicinal chemistry.

Aryl urea derivatives of spiropiperidines as NPY Y5 receptor antagonists.

H. Iwaasa, T. Ohe, A. Kanatani, 2009, Bioorganic & medicinal chemistry letters.

Stereoselective synthesis of J-104,118 and J-104,123, novel, potent inhibitors of squalene synthase

Y. Iwasawa, J. Shibata, H. Masaki, 1996 .

Efficient and Stereoselective Synthesis of J-104,118, a Novel, Potent Inhibitor of Squalene Synthase.

Y. Iwasawa, K. Tomimoto, K. Nonoshita, 1996 .