A. Hatton

发表

Analysis of nasal potential in murine cystic fibrosis models.

J. Jais, I. Sermet-Gaudelus, A. Edelman, 2016, The international journal of biochemistry & cell biology.

Resolvin D1 regulates epithelial ion transport and inflammation in cystic fibrosis airways.

B. Harvey, I. Sermet-Gaudelus, V. Urbach, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Reclassifying inconclusive diagnosis after newborn screening for cystic fibrosis. Moving forward.

M. Claustres, I. Sermet-Gaudelus, E. Girodon, 2021, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Factors influencing readthrough therapy for frequent cystic fibrosis premature termination codons

O. Namy, L. Bidou, Matthieu Coupet, 2018, ERJ Open Research.

Predictive factors for lumacaftor/ivacaftor clinical response.

I. Sermet-Gaudelus, E. Girodon, A. Edelman, 2019, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9

M. Bacchetta, J. Concordet, M. Chanson, 2019, Animal models and experimental medicine.

Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849 + 10 kb C-to-T splicing mutation

B. Kerem, L. Carmel, E. Kerem, 2021, bioRxiv.

Might Brushed Nasal Cells Be a Surrogate for CFTR Modulator Clinical Response?

I. Sermet-Gaudelus, A. Edelman, T. Flament, 2019, American journal of respiratory and critical care medicine.

Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis

L. Touqui, J. Sallenave, X. Nassif, 2019, Scientific Reports.

Correction of CFTR function in nasal epithelial cells from cystic fibrosis patients predicts improvement of respiratory function by CFTR modulators

J. Jais, I. Sermet-Gaudelus, A. Edelman, 2017, Scientific Reports.

Genetic deletion of keratin 8 corrects the altered bone formation and osteopenia in a mouse model of cystic fibrosis.

K. Zatloukal, E. Laplantine, V. Geoffroy, 2016, Human molecular genetics.

The U UGA C sequence provides a favorable context to ELX-02 induced CFTR readthrough.

O. Namy, P. Reix, L. Bidou, 2022, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Correlating genotype with phenotype using CFTR‐mediated whole‐cell Cl− currents in human nasal epithelial cells

I. Sermet-Gaudelus, N. Servel, D. Sheppard, 2021, The Journal of physiology.

Pseudomonas aeruginosa LasB protease impairs innate immunity in mice and humans by targeting a lung epithelial cystic fibrosis transmembrane regulator–IL-6–antimicrobial–repair pathway

A. Cazes, J. Sallenave, I. Sermet-Gaudelus, 2017, Thorax.

Isolation, cultivation, and application of primary respiratory epithelial cells obtained by nasal brushing, polyp samples, or lung explants

I. Sermet, D. Downey, L. Galietta, 2022, STAR protocols.

Sweat Chloride Testing and Nasal Potential Difference (NPD) Are Primary Outcome Parameters in Treatment with Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulators

I. Sermet-Gaudelus, T. Nguyen-Khoa, I. Pranke, 2021, Journal of personalized medicine.

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis.

P. Corringer, G. Lukács, F. Saul, 2016, Journal of molecular biology.

Systemic bis-phosphinic acid derivative restores chloride transport in Cystic Fibrosis mice

J. Jais, C. Schreiweis, S. Moriceau, 2022, Scientific Reports.

New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation

J. Mornon, I. Sermet-Gaudelus, I. Callebaut, 2021, Scientific Reports.

Unsolved severe chronic rhinosinusitis elucidated by extensive CFTR genotyping

S. Simon, I. Sermet-Gaudelus, I. Callebaut, 2019, Clinical case reports.

25 Unsolved severe chronic rhinosinusitis elucidated by extensive CFTR genotyping

S. Simon, I. Sermet-Gaudelus, I. Callebaut, 2017 .

Changes of CFTR functional measurements and clinical improvements in cystic fibrosis patients with non p.Gly551Asp gating mutations treated with ivacaftor.

I. Sermet-Gaudelus, M. Wilschanski, T. Nguyen-Khoa, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Modulation of Chromatin Remodelling Induced by the Freshwater Cyanotoxin Cylindrospermopsin in Human Intestinal Caco-2 Cells

V. Fessard, Y. Blanchard, A. Huguet, 2014, PloS one.

An unexpected effect of TNF-α on F508del-CFTR maturation and function

I. Sermet-Gaudelus, N. Servel, A. Edelman, 2015, F1000Research.

Nonsense mutations accelerate lung disease and decrease survival of cystic fibrosis children.

B. Kerem, P. Reix, P. Burgel, 2023, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Rattlesnake Phospholipase A2 Increases CFTR-Chloride Channel Current and Corrects ∆F508CFTR Dysfunction: Impact in Cystic Fibrosis.

P. Corringer, G. Lukács, F. Saul, 2016, Journal of molecular biology.

TLN468 changes the pattern of tRNA used to read through premature termination codons in CFTR

O. Namy, L. Bidou, I. Sermet-Gaudelus, 2024, bioRxiv.

Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells

A. Ramalho, A. Cereseto, M. Ensinck, 2024, Cell reports. Medicine.

Putting bicarbonate on the spot: pharmacological insights for CFTR correction in the airway epithelium

A. Hinzpeter, Mairead Kelly-Aubert, L. Galietta, 2023, Frontiers in pharmacology.

Putting Bicarbonate on the spot. Implication for theratyping in Cystic Fibrosis

I. Sermet-Gaudelus, A. Edelman, A. Hinzpeter, 2023, medRxiv.

Pseudomonas aeruginosa elastase LasB modulates CFTR expression and innate immune responses in airway epithelial cells

J. Sallenave, A. Edelman, A. Hatton, 2015 .

An unexpected effect of TNF-α on F508del-CFTR maturation and function.

I. Sermet-Gaudelus, N. Servel, A. Edelman, 2015, F1000Research.

Theratyping cystic fibrosis patients to guide elexacaftor/tezacaftor/ivacaftor out-of-label prescription

P. Reix, A. Guillaumot, I. Sermet-Gaudelus, 2023, European Respiratory Journal.