Maria Marco

发表

Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity

P. Rathod, John White, M. Phillips, 2016, Journal of medicinal chemistry.

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity

S. Norval, Frederick R. C. Simeons, L. Stojanovski, 2020, Journal of medicinal chemistry.

University of Dundee Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity

S. Norval, Frederick R. C. Simeons, L. Stojanovski, 2020 .

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017 .

Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease.

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2022, European journal of medicinal chemistry.

Structure-guided lead optimization of triazolopyrimidine-ring substituents identifies potent Plasmodium falciparum dihydroorotate dehydrogenase inhibitors with clinical candidate potential.

David M. Shackleford, Francisco-Javier Gamo, Xiaoyi Deng, 2011, Journal of medicinal chemistry.

The Qi Site of Cytochrome b is a Promiscuous Drug Target in Trypanosoma cruzi and Leishmania donovani

Juan A. Bueren-Calabuig, I. Gilbert, A. Fairlamb, 2020, ACS infectious diseases.

Falcipain inhibition as a promising antimalarial target.

Maria Marco, Jose Miguel Coterón, J. Coterón, 2012, Current topics in medicinal chemistry.

Scaffold-Hopping Strategy on a Series of Proteasome Inhibitors Led to a Preclinical Candidate for the Treatment of Visceral Leishmaniasis

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2021, Journal of medicinal chemistry.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

Juan A. Bueren-Calabuig, David W. Gray, Frederick R. C. Simeons, 2019, Proceedings of the National Academy of Sciences.

Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

A. Hill, Frederick R. C. Simeons, L. Stojanovski, 2017, Journal of medicinal chemistry.

Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals

S. Norval, I. Gilbert, A. Fairlamb, 2018, Antimicrobial Agents and Chemotherapy.

University of Dundee Anti-trypanosomal 8-hydroxyl naphthyridines are chelators of divalent transition metals

S. Norval, I. Gilbert, A. Fairlamb, 2018 .

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform

E. Alvarez, Gonzalo Colmenarejo, J. G. Mina, 2018, Scientific Reports.

Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series.

Juan Miguel, Jiri Gut, Maria Marco, 2010, Journal of medicinal chemistry.

Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors

Peter G. Dodd, Frederick R. C. Simeons, L. Stojanovski, 2023, Journal of medicinal chemistry.

Identifying inhibitors of the Leishmania inositol phosphorylceramide synthase with antiprotozoal activity using a yeast-based assay and ultra-high throughput screening platform

E. Alvarez, Gonzalo Colmenarejo, P. Denny, 2018, Scientific Reports.

Chagas Disease Drug Discovery: Multiparametric Lead Optimization against Trypanosoma cruzi in AcylAminoBenzothiazole series.

Ignacio Cotillo, R. Tarleton, G. Courtemanche, 2019, Journal of medicinal chemistry.