S. Peng

发表

Control of Spontaneous HPV16 E6/E7 Expressing Oral Cancer in HLA-A2 (AAD) Transgenic Mice with Therapeutic HPV DNA Vaccine

T. Wu, C. Hung, L. Ferrall, 2021, Journal of biomedical science.

DNA vaccines delivered by human papillomavirus pseudovirions as a promising approach for generating antigen-specific CD8+ T cell immunity

T. Wu, Shu-Hsia Chen, C. Hung, 2011, Cell & Bioscience.

Cluster intradermal DNA vaccination rapidly induces E7-specific CD8+ T-cell immune responses leading to therapeutic antitumor effects

T. Wu, R. Alvarez, W. Huh, 2008, Gene Therapy.

Sequential Cisplatin Therapy and Vaccination with HPV16 E6E7L2 Fusion Protein in Saponin Adjuvant GPI-0100 for the Treatment of a Model HPV16+ Cancer

R. Roden, T. Wu, S. Pai, 2015, PloS one.

Prophylactic immunization with human papillomavirus vaccines induces oral immunity in mice

R. Roden, J. Ahn, S. Best, 2018, The Laryngoscope.

Characterization of human papillomavirus type 11‐specific immune responses in a preclinical model

J. Saunders, P. Flint, D. Tunkel, 2010, The Laryngoscope.

Programmed self-assembly of peptide–major histocompatibility complex for antigen-specific immune modulation

T. Wu, Chih-Ping Mao, C. Hung, 2018, Proceedings of the National Academy of Sciences.

MHC-Ig induces memory T cell formation in vivo and inhibits tumour growth

J. Schneck, M. Oelke, C. Schütz, 2014, Immunity, inflammation and disease.

Type specific and genotype cross reactive B epitopes of the L1 protein of HPV16 defined by a panel of monoclonal antibodies.

I. Frazer, D. Galloway, J. Kulski, 1998, Virology.

Immunologic responses to a novel DNA vaccine targeting human papillomavirus‐11 E6E7

R. Roden, J. Ahn, S. Best, 2017, The Laryngoscope.

Structure-function analyses of candidate small molecule RPN13 inhibitors with antitumor properties

Tian-Li Wang, R. Roden, Samarjit Das, 2020, PloS one.

Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination

R. Roden, T. Wu, C. Hung, 2015, Cell & Bioscience.

Vascular disrupting agent DMXAA enhances the antitumor effects generated by therapeutic HPV DNA vaccines

T. Wu, C. Hung, A. Monie, 2011, Journal of Biomedical Science.

RNA interference-mediated in vivo silencing of fas ligand as a strategy for the enhancement of DNA vaccine potency.

T. Wu, Chih-Ping Mao, C. Hung, 2008, Human gene therapy.

Intradermal administration of DNA vaccines combining a strategy to bypass antigen processing with a strategy to prolong dendritic cell survival enhances DNA vaccine potency.

T. Wu, Chih-Ping Mao, C. Hung, 2007, Vaccine.

Combination of proteasome and HDAC inhibitor enhances HPV16 E7-specific CD8+ T cell immune response and antitumor effects in a preclinical cervical cancer model

C. Hung, T. Wu, J. Knoff, 2015, Journal of Biomedical Science.

Identification of human MHC-I HPV18 E6/E7-specific CD8 + T cell epitopes and generation of an HPV18 E6/E7-expressing adenosquamous carcinoma in HLA-A2 transgenic mice

D. Xing, T. Wu, C. Hung, 2022, Journal of Biomedical Science.

Preparation and properties of a papillomavirus infectious intermediate and its utility for neutralization studies.

R. Roden, R. Kirnbauer, Kihyuck Kwak, 2014, Virology.

Intramuscular vaccination targeting mucosal tumor draining lymph node enhances integrins-mediated CD8+ T cell infiltration to control mucosal tumor growth

T. Wu, C. Hung, Li-ping Han, 2018, Oncoimmunology.

Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus

T. Wu, C. Hung, Q. Zeng, 2017, Cell & Bioscience.

Production of Furin‐Cleaved Papillomavirus Pseudovirions and Their Use for In Vitro Neutralization Assays of L1‐ or L2‐Specific Antibodies

R. Roden, L. Pinto, T. Kemp, 2015, Current protocols in microbiology.

Stressing the Ubiquitin-Proteasome System without 20S Proteolytic Inhibition Selectively Kills Cervical Cancer Cells

R. Roden, R. Gavioli, Federica Destro, 2011, PloS one.

Papillomavirus virus-like particles can deliver defined CTL epitopes to the MHC class I pathway.

I. Frazer, G. Fernando, J. Zhou, 1998, Virology.

Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine

J. Saunders, T. Wu, S. Pai, 2012, Cancer Immunology, Immunotherapy.

Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma.

J. Taube, C. Drake, Lieping Chen, 2013, Cancer research.

Control of cervicovaginal HPV-16 E7-expressing tumors by the combination of therapeutic HPV vaccination and vascular disrupting agents.

T. Wu, C. Hung, A. Monie, 2011, Human gene therapy.

Papillomavirus Infection Requires γ Secretase

R. Roden, B. Karanam, C. Buck, 2010, Journal of Virology.

Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 Infection

R. Roden, Tsui-Chin Huang, S. Best, 2017, Journal of Virology.

Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity.

P. Stern, R. Roden, B. Karanam, 2009, Vaccine.

Immunologic Control of Mus musculus Papillomavirus Type 1

R. Roden, C. Hung, S. Peng, 2015, PLoS pathogens.

Optimization of heterologous DNA-prime, protein boost regimens and site of vaccination to enhance therapeutic immunity against human papillomavirus-associated disease

R. Roden, T. Wu, C. Brayton, 2016, Cell & Bioscience.

Moderate Reduction of γ-Secretase Attenuates Amyloid Burden and Limits Mechanism-Based Liabilities

H. Wen, D. Price, P. Wong, 2007, The Journal of Neuroscience.

A Phase I Trial of a Human Papillomavirus DNA Vaccine for HPV16+ Cervical Intraepithelial Neoplasia 2/3

D. Pardoll, T. Wu, E. Sugar, 2009, Clinical Cancer Research.

A bis-benzylidine piperidone targeting proteasome ubiquitin receptor RPN13/ADRM1 as a therapy for cancer.

R. Roden, R. Orlowski, M. Rudek, 2013, Cancer cell.

Control of HPV-associated tumors by innovative therapeutic HPV DNA vaccine in the absence of CD4+ T cells

R. Roden, T. Wu, R. Alvarez, 2014, Cell & Bioscience.

Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation

T. Wu, C. Hung, Yunyan Sun, 2017, Gene Therapy.

Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors

T. Wu, Y. Sun, C. Hung, 2015, Gene Therapy.

Spontaneous Regression of High-Grade Cervical Dysplasia: Effects of Human Papillomavirus Type and HLA Phenotype

S. Piantadosi, K. Shah, R. Roden, 2005, Clinical Cancer Research.

Ectopic expression of vascular cell adhesion molecule-1 as a new mechanism for tumor immune evasion.

E. Jaffee, D. Pardoll, T. Wu, 2007, Cancer research.

Development of a Spontaneous HPV16 E6/E7-Expressing Head and Neck Squamous Cell Carcinoma in HLA-A2 Transgenic Mice

D. Xing, R. Roden, T. Wu, 2022, mBio.

Strategy for eliciting antigen-specific CD8+ T cell-mediated immune response against a cryptic CTL epitope of merkel cell polyomavirus large T antigen

T. Wu, Connie Wang, R. Viscidi, 2012, Cell & Bioscience.

Development of a DNA vaccine targeting Merkel cell polyomavirus.

Chien-Fu Hung, T. Wu, R. Viscidi, 2012, Vaccine.

Development of a DNA Vaccine Targeting Human Papillomavirus Type 16 Oncoprotein E6

Chien-Fu Hung, T. Wu, C. Hung, 2004, Journal of Virology.

PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model

R. Roden, T. Wu, C. Hung, 2020, Cancer Immunology, Immunotherapy.

Integration of Oncogenes via Sleeping Beauty as a Mouse Model of HPV16+ Oral Tumors and Immunologic Control

T. Wu, C. Hung, E. Farmer, 2018, Cancer Immunology Research.

Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody

R. Roden, T. Wu, Chuan-Hsiang Huang, 2021, mBio.

Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors

R. Roden, T. Wu, S. Pai, 2013, Clinical Cancer Research.

Characterization of HLA-A2-restricted HPV-16 E7-specific CD8+ T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice

T. Wu, C. Hung, D. Pardoll, 2006, Gene Therapy.

Generation and Characterization of DNA Vaccines Targeting the Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus

Tae Woo Kim, R. Roden, T. Wu, 2004, Journal of Virology.

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer

R. Roden, M. Dyba, M. Rudek, 2018, ACS omega.

Combination of Proteasome and HDAC Inhibitors for Uterine Cervical Cancer Treatment

Kwun Chuen Gary Chan, R. Roden, M. Bazzaro, 2009, Clinical Cancer Research.

Combination of proteasome and HDAC inhibitor enhances HPV16 E7-specific CD8+ T cell immune response and antitumor effects in a preclinical cervical cancer model

C. Hung, T. Wu, J. Knoff, 2015, Journal of Biomedical Science.

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery.

J. Saunders, T. Wu, S. Pai, 2009, Vaccine.

Naturally occurring systemic immune responses to HPV antigens do not predict regression of CIN2/3

C. Thoburn, F. Kos, C. Trimble, 2010, Cancer Immunology, Immunotherapy.

Characterization of HPV-16 E6 DNA vaccines employing intracellular targeting and intercellular spreading strategies.

T. Wu, B. Macaes, C. Hung, 2005, Journal of biomedical science.

Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope

T. Wu, C. Hung, D. Boyd, 2005, Gene Therapy.

Identification of the murine H-2Db and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes

J. Burns, A. Mattox, S. Pai, 2016, Cancer Immunology, Immunotherapy.

Epithelial boost enhances antigen expression by vaccinia virus for the generation of potent CD8+ T cell-mediated antitumor immunity following DNA priming vaccination.

R. Roden, T. Wu, C. Hung, 2018, Virology.

Local HPV Recombinant Vaccinia Boost Following Priming with an HPV DNA Vaccine Enhances Local HPV-Specific CD8+ T-cell–Mediated Tumor Control in the Genital Tract

R. Roden, T. Wu, C. Hung, 2015, Clinical Cancer Research.

Local administration of granulocyte macrophage colony-stimulating factor induces local accumulation of dendritic cells and antigen-specific CD8+ T cells and enhances dendritic cell cross-presentation.

T. Wu, Chih-Ping Mao, C. Hung, 2015, Vaccine.

Differential expression of epidermal growth factor receptor in juvenile and adult‐onset recurrent respiratory papillomatosis

J. Saunders, P. Flint, W. Westra, 2010, Histopathology.

Microenvironment and Immunology Evidence for a Role of the PD-1 : PD-L 1 Pathway in Immune Resistance of HPV-Associated Head and Neck Squamous Cell Carcinoma

J. Taube, C. Drake, Lieping Chen, 2013 .

Characterization of HPV18 E6-specific T cell responses and establishment of HPV18 E6-expressing tumor model.

T. Wu, C. Hung, E. Farmer, 2017, Vaccine.

HLA-DQB1*02–Restricted HPV-16 E7 Peptide–Specific CD4+ T-Cell Immune Responses Correlate with Regression of HPV-16–Associated High-Grade Squamous Intraepithelial Lesions

R. Roden, D. Pardoll, T. Wu, 2007, Clinical Cancer Research.

Co-administration with DNA encoding papillomavirus capsid proteins enhances the antitumor effects generated by therapeutic HPV DNA vaccination

R. Roden, T. Wu, C. Hung, 2015, Cell & Bioscience.

Enhancing dendritic cell vaccine potency by combining a BAK/BAX siRNA‐mediated antiapoptotic strategy to prolong dendritic cell life with an intracellular strategy to target antigen to lysosomal compartments

Tae Woo Kim, T. Wu, K. Noh, 2007, International journal of cancer.

Vaccination with dendritic cells transfected with BAK and BAX siRNA enhances antigen-specific immune responses by prolonging dendritic cell life.

Tae Woo Kim, T. Wu, C. Hung, 2005, Human gene therapy.

A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects

T. Wu, C. Hung, Liangmei He, 2006, Gene Therapy.

Enhancing antitumor immunogenicity of HPV16-E7 DNA vaccine by fusing DNA encoding E7-antigenic peptide to DNA encoding capsid protein L1 of Bovine papillomavirus

T. Wu, C. Hung, Q. Zeng, 2017, Cell & Bioscience.

Innovative DNA Vaccine for Human Papillomavirus (HPV)-Associated Head and Neck Cancer

S. Pai, C. Hung, T. Kang, 2010, Gene Therapy.

In vivo microRNA-155 expression influences antigen-specific T cell-mediated immune responses generated by DNA vaccination

T. Wu, Chih-Ping Mao, C. Hung, 2011, Cell & Bioscience.

Efficient Delivery of DNA Vaccines using Human Papillomavirus Pseudovirions

R. Roden, T. Wu, C. Hung, 2010, Gene Therapy.

Epithelial cells display separate receptors for papillomavirus VLPs and for soluble L1 capsid protein.

I. Frazer, Y. Qi, M. Evander, 1996, Virology.

Characterization of human papillomavirus type 11‐specific immune responses in a preclinical model

D. Tunkel, S. Best, C. Hung, 2010, The Laryngoscope.

Immune responses, therapeutic anti-tumor effects, and tolerability upon therapeutic HPV16/18 E6/E7 DNA vaccination via needle-free biojector

R. Roden, C. Hung, Y. Tsai, 2023, mBio.