Bernd Nidetzky

发表

Novel High Throughput Screening Methodologies to Advance Directed Evolution of Glycosyltransferases

Patricia Bubner, Christiane Luley, Sigrid Egger, 2010 .

Patricia Bubner, Bernd Nidetzky, 2011 .

Freezing Process Development under QbD Principles - In-silico Solutions for Process Characterization and Scaling

Bernd Nidetzky, Dalibor Jajcevic, Ulrich Rößl, 2013 .

Sustainability assessment integrated in bioprocess design in H2020 Project CARBAFIN: When thinking about process optimization - are we also thinking about environmental aspects?

Alexander Passer, Bernd Nidetzky, René Kollmann, 2019 .

Glycosyltransferases: On the way towards industrial biocatalysts

Bernd Nidetzky, Katharina Schmoelzer, Alexander Gutmann, 2014 .

Evaluation methodology and multi-level engineering approach to improve whole cell ketone reduction

John M. Woodley, Bernd Nidetzky, Regina Kratzer, 2009 .

Model-based analysis of biocatalytic processes and performance of microbioreactors with integrated optical sensors.

Alexandr Zubov, Krist V Gernaey, Ana C Fernandes, 2019, New biotechnology.

In situ protein secondary structure determination in ice: Raman spectroscopy-based process analytical tool for frozen storage of biopharmaceuticals.

Bernd Nidetzky, Thomas De Beer, Stefan Leitgeb, 2014, Journal of pharmaceutical sciences.

Human Enzymes for Organic Synthesis

Bernd Nidetzky, Martina Geier, Anton Glieder, 2018, Angewandte Chemie.

Enzymatic synthesis of β‐glucosylglycerol using a continuous‐flow microreactor containing thermostable β‐glycoside hydrolase CelB immobilized on coated microchannel walls

Bernd Nidetzky, B. Nidetzky, A. Schwarz, 2009, Biotechnology and bioengineering.

Structure Based Descriptors for the Estimation of Colloidal Interactions and Protein Aggregation Propensities

Bernd Nidetzky, B. Nidetzky, M. Brunsteiner, 2013, PloS one.

Bioprocess design guided by in situ substrate supply and product removal: Process intensification for synthesis of (S)-1-(2-chlorophenyl)ethanol

Bernd Nidetzky, Regina Kratzer, B. Nidetzky, 2012, Bioresource technology.

Multivalency Effects on the Immobilization of Sucrose Phosphorylase in Flow Microchannels and Their Use in the Development of a High‐Performance Biocatalytic Microreactor

Bernd Nidetzky, B. Nidetzky, Donya Valikhani, 2017 .

Positively charged mini-protein Zbasic2 as a highly efficient silica binding module: opportunities for enzyme immobilization on unmodified silica supports.

Bernd Nidetzky, Juan M Bolivar, B. Nidetzky, 2012, Langmuir : the ACS journal of surfaces and colloids.

Candida tenuis xylose reductase catalysed reduction of acetophenones: the effect of ring-substituents on catalytic efficiency.

Lothar Brecker, Bernd Nidetzky, Regina Kratzer, 2011, Organic & biomolecular chemistry.

Quantitating intraparticle O2 gradients in solid supported enzyme immobilizates: Experimental determination of their role in limiting the catalytic effectiveness of immobilized glucose oxidase

Bernd Nidetzky, Torsten Mayr, Juan M Bolivar, 2013, Biotechnology and bioengineering.

Diastereoselective Synthesis of Glycosyl Phosphates by Using a Phosphorylase–Phosphatase Combination Catalyst

Lothar Brecker, Bernd Nidetzky, B. Nidetzky, 2015, Angewandte Chemie.

Process intensification for O2‐dependent enzymatic transformations in continuous single‐phase pressurized flow

Bernd Nidetzky, Juan M Bolivar, B. Nidetzky, 2019, Biotechnology and bioengineering.

Demystifying the Flow: Biocatalytic Reaction Intensification in Microstructured Enzyme Reactors.

Bernd Nidetzky, Juan M Bolivar, B. Nidetzky, 2018, Biotechnology journal.

Cellular automata modeling depicts degradation of cellulosic material by a cellulase system with single-molecule resolution

Bernd Nidetzky, Harald Plank, B. Nidetzky, 2016, Biotechnology for Biofuels.

Rules for biocatalyst and reaction engineering to implement effective, NAD(P)H-dependent, whole cell bioreductions

John M. Woodley, Bernd Nidetzky, Regina Kratzer, 2015, Biotechnology advances.

Altering the coenzyme preference of xylose reductase to favor utilization of NADH enhances ethanol yield from xylose in a metabolically engineered strain of Saccharomyces cerevisiae

Bernd Nidetzky, Barbara Petschacher, B. Nidetzky, 2008, Microbial cell factories.

Identification of Candida tenuis xylose reductase as highly selective biocatalyst for the synthesis of aromatic alpha-hydroxy esters and improvement of its efficiency by protein engineering.

Bernd Nidetzky, Regina Kratzer, B. Nidetzky, 2007, Chemical communications.

Intensifying the O2-dependent heterogeneous biocatalysis: Superoxygenation of solid support from H2O2 by a catalase tailor-made for effective immobilization

Bernd Nidetzky, B. Nidetzky, Juan M. Bolívar, 2016 .

Design of experiments reveals critical parameters for pilot-scale freeze-and-thaw processing of L-lactic dehydrogenase.

Bernd Nidetzky, Stefan Leitgeb, B. Nidetzky, 2015, Biotechnology journal.

Downstream Processing of Nucleoside‐Diphospho‐Sugars from Sucrose Synthase Reaction Mixtures at Decreased Solvent Consumption

Bernd Nidetzky, Alexander Gutmann, B. Nidetzky, 2016 .

Development of a microfluidic immobilised enzyme reactor.

Bernd Nidetzky, Peter Pölt, B. Nidetzky, 2007, Chemical communications.

Simultaneous Enzymatic Synthesis of Mannitol and Gluconic Acid: II. Development of a Continuous Process for a Coupled Nad(H)-Dependent Enzyme System

Dietmar Haltrich, Bernd Nidetzky, D. Haltrich, 1996 .

Tunable Semicrystalline Thin Film Cellulose Substrate for High-Resolution, In-Situ AFM Characterization of Enzymatic Cellulose Degradation.

Bernd Nidetzky, Harald Plank, Werner Grogger, 2015, ACS applied materials & interfaces.

Shaking and stirring: Comparison of controlled laboratory stress conditions applied to the human growth hormone

Bernd Nidetzky, Massimiliano Cardinale, B. Nidetzky, 2013 .

CorNet: Assigning function to networks of co-evolving residues by automated literature mining

Bas Vroling, Tom van den Bergh, Gert Vriend, 2017, PloS one.

Enzymatic Redox Cascade for One-Pot Synthesis of Uridine 5′-Diphosphate Xylose from Uridine 5′-Diphosphate Glucose

Bernd Nidetzky, B. Nidetzky, T. Eixelsberger, 2014, Advanced synthesis & catalysis.

Coated‐wall microreactor for continuous biocatalytic transformations using immobilized enzymes

Bernd Nidetzky, B. Nidetzky, Malene S Thomsen, 2009, Biotechnology journal.

Microfluidic Reactor for Continuous Flow Biotransformations with Immobilized Enzymes: the Example of Lactose Hydrolysis by a Hyperthermophilic β_cont;‐Glycoside Hydrolase

Bernd Nidetzky, B. Nidetzky, M. S. Thomsen, 2008 .

The Cetus Process Revisited: A Novel Enzymatic Alternative for the Production of Aldose-Free D-Fructose

Dietmar Haltrich, Bernd Nidetzky, D. Haltrich, 1998 .

Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase.

Bernd Nidetzky, Mario Klimacek, M. Klimacek, 2007, The Biochemical journal.

Studying non-covalent enzyme carbohydrate interactions by STD NMR.

Lothar Brecker, Bernd Nidetzky, Regina Kratzer, 2008, Carbohydrate research.

Crystal Structure of Pseudomonas fluorescens Mannitol 2-Dehydrogenase Binary and Ternary Complexes

Bernd Nidetzky, Mario Klimacek, K. Kavanagh, 2002, The Journal of Biological Chemistry.

Enzymatic Production of Pure D-Mannitol at High Productivity

Dietmar Haltrich, Bernd Nidetzky, D. Haltrich, 1998 .

Decoupling of recombinant protein production from Escherichia coli cell growth enhances functional expression of plant Leloir glycosyltransferases

Bernd Nidetzky, Rainer Hahn, B. Nidetzky, 2019, Biotechnology and bioengineering.

Multiphase biotransformations in microstructured reactors: opportunities for biocatalytic process intensification and smart flow processing

Bernd Nidetzky, B. Nidetzky, Juan M. Bolívar, 2013 .

Fusion to a pull‐down domain: a novel approach of producing Trigonopsis variabilisD‐amino acid oxidase as insoluble enzyme aggregates

Bernd Nidetzky, Jozef Nahalka, B. Nidetzky, 2007, Biotechnology and bioengineering.

Smart enzyme immobilization in microstructured reactors

Bernd Nidetzky, B. Nidetzky, Juan M. Bolívar, 2013 .

Stepwise metabolic adaption from pure metabolization to balanced anaerobic growth on xylose explored for recombinant Saccharomyces cerevisiae

Bernd Nidetzky, Mario Klimacek, M. Klimacek, 2014, Microbial Cell Factories.

Leloir Glycosyltransferases as Biocatalysts for Chemical Production

Bernd Nidetzky, Alexander Gutmann, B. Nidetzky, 2018 .

Let the substrate flow, not the enzyme: Practical immobilization of d‐amino acid oxidase in a glass microreactor for effective biocatalytic conversions

Bernd Nidetzky, Juan M Bolivar, Zdenek Petrasek, 2016, Biotechnology and bioengineering.

Integration of whole-cell reaction and product isolation: Highly hydrophobic solvents promote in situ substrate supply and simplify extractive product isolation.

Bernd Nidetzky, Regina Kratzer, A. Pfennig, 2017, Journal of biotechnology.

Glycosyltransferase cascades made fit for chemical production: Integrated biocatalytic process for the natural polyphenol C‐glucoside nothofagin

Bernd Nidetzky, B. Nidetzky, M. Lemmerer, 2018, Biotechnology and bioengineering.

Stepwise engineering of a Pichia pastoris D-amino acid oxidase whole cell catalyst

Bernd Nidetzky, Anton Glieder, Ian Fotheringham, 2010, Microbial cell factories.

Biotransformations in microstructured reactors: more than flowing with the stream?

Bernd Nidetzky, Juan M Bolivar, B. Nidetzky, 2011, Trends in biotechnology.

Preparative Asymmetric Synthesis of Canonical and Non‐canonical α‐amino Acids Through Formal Enantioselective Biocatalytic Amination of Carboxylic Acids

Bernd Nidetzky, Alexander Dennig, B. Nidetzky, 2019, Advanced Synthesis & Catalysis.

Nutritional requirements of the BY series of Saccharomyces cerevisiae strains for optimum growth.

David E. Ruckerbauer, Klaus Natter, Bernd Nidetzky, 2012, FEMS yeast research.

Structure‐guided engineering of the coenzyme specificity of Pseudomonas fluorescens mannitol 2‐dehydrogenase to enable efficient utilization of NAD(H) and NADP(H)

Bernd Nidetzky, Mario Klimacek, M. Klimacek, 2008, FEBS letters.

Integrated process design for biocatalytic synthesis by a Leloir Glycosyltransferase: UDP-glucose production with sucrose synthase.

Bernd Nidetzky, Alexander Gutmann, B. Nidetzky, 2017, Biotechnology and bioengineering.

Hydrolysis of cellooligosaccharides by Trichoderma reesei cellobiohydrolases: Experimental data and kinetic modeling

Bernd Nidetzky, Walter Steiner, W. Steiner, 1994 .

Production of glucosyl glycerol by immobilized sucrose phosphorylase: Options for enzyme fixation on a solid support and application in microscale flow format.

Bernd Nidetzky, Christiane Luley-Goedl, Juan M Bolivar, 2017, Journal of biotechnology.

Process intensification through microbial strain evolution: mixed glucose-xylose fermentation in wheat straw hydrolyzates by three generations of recombinant Saccharomyces cerevisiae

Bernd Nidetzky, Mario Klimacek, M. Klimacek, 2014, Biotechnology for Biofuels.