D. Denhart

发表

Aminotriazine 5-HT7 antagonists.

M. Poss, D. Tortolani, A. Purandare, 2004, Bioorganic & medicinal chemistry letters.

In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Vijay T. Ahuja, J. Macor, H. Wong, 2009, Journal of medicinal chemistry.

Neurochemical, pharmacokinetic, and behavioral effects of the novel selective serotonin reuptake inhibitor BMS-505130

T. Molski, R. Mattson, N. Lodge, 2005, Pharmacology Biochemistry and Behavior.

A strategy to minimize reactive metabolite formation: discovery of (S)-4-(1-cyclopropyl-2-methoxyethyl)-6-[6-(difluoromethoxy)-2,5-dimethylpyridin-3-ylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile as a potent, orally bioavailable corticotropin-releasing factor-1 receptor antagonist.

Vijay T. Ahuja, J. Macor, Y. Shu, 2009, Journal of medicinal chemistry.

A new approach to the bicyclic hydroxylamine hemiketal ring system of antitumour-antibiotic FR900482 via oxidative ring expansion of a tetrahydropyrrolo[1,2-a]indole

N. Taylor, G. Dmitrienko, D. Denhart, 1992 .

Enantioselective Synthesis of a Highly Potent Selective Serotonin Reuptake Inhibitor. An Application of Imidazolidinone Catalysis to the Alkylation of Indoles with an α,β-Disubstituted α,β-Unsaturated Aldehyde

J. Macor, R. Mattson, Qi Gao, 2005 .

Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors.

B. Beno, M. Cunningham, T. Molski, 2005, Journal of medicinal chemistry.

SYNTHESIS OF THE TRICYCLIC CORE OF SARAIN A. USE OF FORMALDEHYDE IN AN INTRAMOLECULAR GRIGG AZOMETHINE YLIDE CYCLIZATION

C. Heathcock, D. Griffith, D. Denhart, 1998 .

Conformationally restricted homotryptamines. Part 6: indole-5-cycloalkyl methylamines as selective serotonin reuptake inhibitors.

J. Macor, T. Molski, R. Mattson, 2013, Bioorganic & medicinal chemistry letters.

Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs).

J. Macor, T. Molski, R. Mattson, 2005, Bioorganic & medicinal chemistry letters.

Catalytic asymmetric diazoacetate cyclopropanation of 1-tosyl-3-vinylindoles. A route to conformationally restricted homotryptamines.

R. Mattson, L. Marcin, D. Denhart, 2005, Organic Letters.

On the DNA Recognition Role of the Carbohydrate Sector in Calicheamicin: A Comparison of DNA Cleaving Capacity of Enantiomeric Calicheamicinones

D. Crothers, S. Hitchcock, K. Liu, 1994 .

Potential CRF1R PET imaging agents: 1-fluoroalkylsubstituted 5-halo-3-(arylamino)pyrazin-2(1H)-ones.

Vijay T. Ahuja, J. Macor, D. Zuev, 2013, Bioorganic & medicinal chemistry letters.

Synthesis and a Preliminary DNA Binding Study of Hybrids of the Carbohydrate Domain of Calicheamicin γ 1I and the Aglycone of Daunorubicin: Calichearubicins A and B

D. Crothers, S. Danishefsky, K. Depew, 1996 .

[18F](R)-5-chloro-1-(1-cyclopropyl-2-methoxyethyl)-3-(4-(2-fluoroethoxy)-2,5-dimethyl phenylamino)pyrazin-2(1H)-one: introduction of N3-phenylpyrazinones as potential CRF-R1 PET imaging agents.

Vijay T. Ahuja, J. Macor, T. Molski, 2012, Bioorganic & medicinal chemistry letters.

Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Joseph Payne, Vijay T. Ahuja, Yue-Zhong Shu, 2009, Journal of medicinal chemistry.

Studies Related to the Carbohydrate Sectors of Esperamicin and Calicheamicin: Definition of the Stability Limits of the Esperamicin Domain and Fashioning of a Glycosyl Donor from the Calicheamicin Domain

K. Liu, R. Halcomb, S. Danishefsky, 1995 .

Diaminopyrimidine and diaminopyridine 5-HT7 ligands.

M. Poss, A. Purandare, R. Mattson, 2004, Bioorganic & medicinal chemistry letters.

Conformationally restricted homotryptamines. Part 5: 3-(trans-2-aminomethylcyclopentyl)indoles as potent selective serotonin reuptake inhibitors.

J. Macor, T. Molski, R. Mattson, 2009, Bioorganic & medicinal chemistry letters.

One-pot synthesis of homotryptamines from indoles

J. Macor, D. Denhart, Jonathan L. Ditta, 2004 .