G. Ambrus-Aikelin

发表

Biochemical Properties of TAK-828F, a Potent and Selective Retinoid-Related Orphan Receptor Gamma t Inverse Agonist

Biching Sang, Masaharu Nakayama, Hideyuki Nakagawa, 2018, Pharmacology.

Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor.

Matthew S. Johnson, M. Ultsch, J. Veal, 2022, Journal of medicinal chemistry.

Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.

M. Klein, K. Ogawa, M. Okaniwa, 2020, Journal of medicinal chemistry.

Cholesterol Unbound RORγt Protein Enables a Sensitive Inverse Agonist Screening.

Biching Sang, Masaharu Nakayama, Ryokichi Koyama, 2018, Assay and drug development technologies.

New Series of Potent Allosteric Inhibitors of Deoxyhypusine Synthase

M. Klein, M. Okaniwa, Yuta Tanaka, 2020, ACS medicinal chemistry letters.

Early pathways, biomarkers, and four distinct molecular subclasses of preeclampsia: The intersection of clinical, pathological, and high-dimensional biology studies.

A. Szilágyi, A. Tarca, R. Romero, 2022, Placenta.

DDX1 Is an RNA-Dependent ATPase Involved in HIV-1 Rev Function and Virus Replication

J. Williamson, L. Gerace, A. Saphire, 2011, Journal of Molecular Biology.

Pharmacology of a Potent and Novel Inhibitor of the NOD-Like Receptor Pyrin Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis

J. Veal, A. Feldstein, J. Stafford, 2023, The Journal of Pharmacology and Experimental Therapeutics.

Pharmacology of a Potent and Novel Inhibitor of the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) Inflammasome that Attenuates Development of NASH and Liver Fibrosis

J. Veal, A. Feldstein, Christopher Mcbride, 2023 .

JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders

E. Gelfand, J. Veal, A. Joetham, 2023, Scientific reports.