Y. Taniguchi

发表

A nanocarrier system for the delivery of nucleic acids targeted to a pancreatic beta cell line.

H. Harashima, Yuma Yamada, S. Sasaki, 2014, Biomaterials.

Surprising repair activities of nonpolar analogs of 8-oxoG expose features of recognition and catalysis by base excision repair glycosylases.

E. Kool, S. David, A. Kobori, 2012, Journal of the American Chemical Society.

Modification of the aminopyridine unit of 2′-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences

S. Sasaki, Y. Taniguchi, Lei Wang, 2018, Nucleic acids research.

Efficient Thymidine-Selective DNA Interstrand Photo-activated Crosslinking by the 6-Thioguanine Connected via an Ethylene-Linker to the 2'-Deoxyribose Unit.

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2016, Chemical & pharmaceutical bulletin.

Oligodeoxynucleotide Containing S‐Functionalized 2′‐Deoxy‐6‐Thioguanosine: Facile Tools for Base‐Selective and Site‐Specific Internal Modification of RNA

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2012, Current protocols in nucleic acid chemistry.

Pin-point chemical modification of RNA with diverse molecules through the functionality transfer reaction and the copper-catalyzed azide-alkyne cycloaddition reaction.

S. Sasaki, Atsushi Shibata, Kazumitsu Onizuka, 2011, Chemical communications.

Synthesis of 8-halogenated-7-deaza-2′-deoxyguanosine as an 8-oxo-2′-deoxyguanosine analogue and evaluation of its base pairing properties

S. Sasaki, Yizhen Yin, Y. Taniguchi, 2014 .

Development of Triplex Forming Oligonucleotide Including Artificial Nucleoside Analogues for the Antigene Strategy

S. Sasaki, Y. Taniguchi, 2018 .

Effect of the 3-halo substitution of the 2'-deoxy aminopyridinyl-pseudocytidine derivatives on the selectivity and stability of antiparallel triplex DNA with a CG inversion site.

S. Sasaki, Y. Taniguchi, Lei Wang, 2017, Bioorganic & medicinal chemistry.

Aminopyridinyl-Pseudodeoxycytidine Derivatives Selectively Stabilize Antiparallel Triplex DNA with Multiple CG Inversion Sites.

S. Sasaki, Y. Taniguchi, Hidenori Okamura, 2016, Angewandte Chemie.

An Isocytidine Derivative with a 2‐Amino‐6‐methylpyridine Unit for Selective Recognition of the CG Interrupting Site in an Antiparallel Triplex DNA

S. Sasaki, Y. Taniguchi, Hidenori Okamura, 2014, Chembiochem : a European journal of chemical biology.

N-(guanidinoethyl)-2'-deoxy-5-methylisocytidine exhibits selective recognition of a CG interrupting site for the formation of anti-parallel triplexes.

S. Sasaki, Y. Taniguchi, Hidenori Okamura, 2013, Organic & biomolecular chemistry.

Selective formation of stable triplexes including a TA or a CG interrupting site with new bicyclic nucleoside analogues (WNA).

F. Nagatsugi, S. Sasaki, M. Maeda, 2004, Journal of the American Chemical Society.

Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives

C. Heh, S. Sasaki, Y. Taniguchi, 2021, International journal of molecular sciences.

Implications of N7-hydrogen and C8-keto on the base pairing, mutagenic potential and repair of 8-oxo-2'-deoxy-adenosine: Investigation by nucleotide analogues.

J. Wu, Junjie Wu, Youming Zhang, 2022, Bioorganic chemistry.

Development of novel C-nucleoside analogues for the formation of antiparallel-type triplex DNA with duplex DNA that includes TA and dUA base pairs.

S. Sasaki, Y. Taniguchi, Lei Wang, 2020, Organic & biomolecular chemistry.

Efficient DNA Strand Displacement by a W‐Shaped Nucleoside Analogue (WNA‐βT) Containing an ortho‐Methyl‐Substituted Phenyl Ring

S. Sasaki, Y. Taniguchi, Eriko Aoki, 2012, Chembiochem : a European journal of chemical biology.

Synthesis of γ-N-modified 8-oxo-2’-deoxyguanosine triphosphate and its characterization

C. Heh, S. Sasaki, Y. Taniguchi, 2019, Nucleosides, nucleotides & nucleic acids.

Alteration of cross-linking selectivity with the 2'-OMe analogue of 2-amino-6-vinylpurine and evaluation of antisense effects.

F. Nagatsugi, S. Sasaki, Shuhei Imoto, 2010, Bioorganic & medicinal chemistry letters.

Adenosine-1,3-diazaphenoxazine derivative for selective base pair formation with 8-oxo-2'-deoxyguanosine in DNA.

S. Sasaki, Y. Taniguchi, Ryota Kawaguchi, 2011, Journal of the American Chemical Society.

Synthesis of new derivatives of 8-oxoG-clamp for better understanding the recognition mode and improvement of selective affinity.

S. Sasaki, O. Nakagawa, Y. Taniguchi, 2010, Bioorganic & medicinal chemistry.

Synthesis of 1′-phenyl-2′-OMe ribose analogues connecting the thymine base at the 1′ position through a flexible linker for the formation of a stable anti-parallel triplex DNA

S. Sasaki, Y. Taniguchi, Hidenori Okamura, 2013 .

Properties of Oligonucleotide with Phenyl-Substituted Carbocyclic Nucleoside Analogs for the Formation of Duplex and Triplex DNA

S. Sasaki, Y. Taniguchi, T. Nasr, 2012, Nucleosides, nucleotides & nucleic acids.

Recognition of CG interrupting site by W-shaped nucleoside analogs (WNA) having the pyrazole ring in an anti-parallel triplex DNA.

S. Sasaki, Y. Uchida, Y. Taniguchi, 2009, Bioorganic & medicinal chemistry.

Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex

S. Sasaki, Y. Uchida, Y. Taniguchi, 2008 .

EXPANSION OF TRIPLEX RECOGNITION CODES BY THE USE OF NOVEL BICYCLIC NUCLEOSIDE DERIVATIVES (WNA)

F. Nagatsugi, S. Sasaki, Y. Taniguchi, 2005, Nucleosides, nucleotides & nucleic acids.

New base analogs for the formation of non-natural triplexes.

S. Sasaki, M. Maeda, Y. Taniguchi, 2001, Nucleic acids research. Supplement.

W-shape nucleic acid (WNA) for selective formation of non-natural anti-parallel triplex including a TA interrupting site

F. Nagatsugi, S. Sasaki, M. Maeda, 2001 .

Coupling Reaction of Alkynyliodonium Salts with Alkynylcopper Reagents. A New Access to Liquid-Crystalline 1,3-Butadiynes

T. Kitamura, Y. Fujiwara, C. Lee, 1996 .

The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA.

F. Nagatsugi, S. Sasaki, Y. Taniguchi, 2010, Bioorganic & medicinal chemistry.

Synthesis of the deuterated thymidine-d and deuterated oligonucleotides

S. Sasaki, Xiuming Cao, Y. Taniguchi, 2019, Tetrahedron Letters.

LANTHANOID-CATALYZED RING-OPENING REACTION OF EPOXIDES WITH ACYL HALIDES

T. Kitamura, Y. Fujiwara, Y. Taniguchi, 1998 .

Lanthanoid-Catalyzed Ring-Opening Reaction of Epoxides with Acyl Halides.

T. Kitamura, Y. Fujiwara, Y. Taniguchi, 1998 .

Lanthanoid‐Metal‐Mediated organic reactions of acyltrialkylsilanes

Y. Fujiwara, K. Takaki, Y. Taniguchi, 1995 .

The ODN probes conjugating the Cu(II) complex enhance the luminol chemiluminescence by assembling on the DNA template.

S. Sasaki, Sun Min Park, A. Kohara, 2010, Bioorganic & medicinal chemistry.

Synthetic Utility of Umpoled Diaryl Thioketone−Lanthanoid Intermediates: Desulfurization, Cross Coupling with Electrophiles, and Desulfurizative Homocoupling

Y. Fujiwara, K. Takaki, Y. Makioka, 1996 .

Selective Unnatural Base Pairing and Recognition of 2-Hydroxy-2'-deoxyadenosine in DNA Using Pseudo-dC Derivatives.

Y. Taniguchi, R. Miyahara, 2022, Journal of the American Chemical Society.

New members of the macrosphelides from Microsphaeropsis sp. FO-5050 IV.

S. Ōmura, M. Hayashi, M. Rho, 1999, The Journal of antibiotics.

Discrimination between 8-oxo-2'-deoxyguanosine and 2'-deoxyguanosine in DNA by the single nucleotide primer extension reaction with adap triphosphate.

S. Sasaki, Y. Taniguchi, Yoshiya Kikukawa, 2015, Angewandte Chemie.

Transformation of Liquid-Crystalline Diaryldiacetylenes to Liquid-Crystalline 2,5-Diarylthiophenes

T. Kitamura, Y. Fujiwara, C. Lee, 1997 .

Synchronized Chiral Induction between [5]Helicene-Spermine Ligand and B-Z DNA Transition.

S. Sasaki, Genichiro Tsuji, Y. Taniguchi, 2017, Chemistry.

Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-Oxoguanine

F. Nagatsugi, S. Sasaki, Y. Taniguchi, 2016 .

Remarkable acceleration of a DNA/RNA inter-strand functionality transfer reaction to modify a cytosine residue: the proximity effect via complexation with a metal cation

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2014, Nucleic acids research.

4-vinyl-substituted pyrimidine nucleosides exhibit the efficient and selective formation of interstrand cross-links with RNA and duplex DNA

F. Nagatsugi, S. Sasaki, Kazumitsu Onizuka, 2013, Nucleic acids research.

Synthesis of C-nucleoside analogues based on the pyrimidine skeleton for the formation of anti-parallel-type triplex DNA with a CG mismatch site.

S. Sasaki, Y. Taniguchi, Lei Wang, 2020, Bioorganic & Medicinal Chemistry.

A New Odorless Procedure for the Synthesis of 2′-Deoxy-6-Thioguanosine and Its Incorporation into Oligodeoxynucleotides

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2009, Nucleosides, nucleotides & nucleic acids.

The oligodeoxynucleotide probes for the site-specific modification of RNA.

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2011, Chemical Society reviews.

Design and synthesis of purine nucleoside analogues for the formation of stable anti-parallel-type triplex DNA with duplex DNA bearing the 5mCG base pair

S. Sasaki, Y. Taniguchi, Lei Wang, 2021, RSC advances.

Synthesis of 2′‐deoxy‐4‐aminopyridinylpseudocytidine Derivatives for Incorporation Into Triplex Forming Oligonucleotides

S. Sasaki, Y. Taniguchi, Lei Wang, 2019, Current protocols in nucleic acid chemistry.

Synthesis of the Oligoribonucleotides Incorporating 8-Oxo-Guanosine and Evaluation of their Base Pairing Properties

S. Sasaki, Y. Taniguchi, Yohei Koga, 2013, Nucleosides, nucleotides & nucleic acids.

Enhancements in the utilization of antigene oligonucleotides in the nucleus by booster oligonucleotides.

S. Sasaki, Y. Taniguchi, Lei Wang, 2020, Chemical communications.

An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT).

S. Sasaki, Y. Taniguchi, 2012, Organic & biomolecular chemistry.

Site‐Specific Modification of the 6‐Amino Group of Adenosine in RNA by an Interstrand Functionality‐Transfer Reaction With an S‐Functionalized 4‐Thiothymidine

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2015, Chembiochem : a European journal of chemical biology.

A new usage of functionalized oligodeoxynucleotide probe for site-specific modification of a guanine base within RNA

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2010, Nucleic acids research.

Site-specific covalent modification of RNA guided by functionality-transfer oligodeoxynucleotides.

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2009, Bioconjugate chemistry.

Development of novel thioguanosine analogs with the ability to specifically modify cytidine.

S. Sasaki, Kazumitsu Onizuka, Y. Taniguchi, 2007, Nucleic acids symposium series.

Development of Damaged Nucleoside Mimics for Inhibition of Their Repair Enzymes.

Y. Taniguchi, 2017, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Effects of 8-halo-7-deaza-2'-deoxyguanosine triphosphate on DNA synthesis by DNA polymerases and cell proliferation.

S. Sasaki, Yizhen Yin, Y. Taniguchi, 2016, Bioorganic & medicinal chemistry.

Inhibitory Effect of 8‐Halogenated 7‐Deaza‐2′‐deoxyguanosine Triphosphates on Human 8‐Oxo‐2′‐deoxyguanosine Triphosphatase, hMTH1, Activities

S. Sasaki, Yizhen Yin, Y. Taniguchi, 2016, Chembiochem : a European journal of chemical biology.

Nonpolar isosteres of damaged DNA bases: effective mimicry of mutagenic properties of 8-oxopurines.

E. Kool, Y. Taniguchi, 2007, Journal of the American Chemical Society.

OFF-to-ON type fluorescent probe for the detection of 8-oxo-dG in DNA by the Adap-masked ODN probe.

S. Sasaki, Y. Taniguchi, Ryota Kawaguchi, 2012, Bioorganic & medicinal chemistry letters.

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate.

M. Ohno, T. Tsuzuki, Masayuki Yamamoto, 2020, Mutation research.

α-Lipoic acid protects against arsenic trioxide-induced acute QT prolongation in anesthetized guinea pigs.

A. Fujimura, M. Kakei, T. Koshimizu, 2013, European journal of pharmacology.

Recognition and Excision Properties of 8‐Halogenated‐7‐Deaza‐2′‐Deoxyguanosine as 8‐Oxo‐2′‐Deoxyguanosine Analogues and Fpg and hOGG1 Inhibitors

S. Sasaki, Yizhen Yin, Y. Taniguchi, 2015, Chembiochem : a European journal of chemical biology.

Stabilization of the i-motif structure by the intra-strand cross-link formation.

F. Nagatsugi, S. Sasaki, Kazumitsu Onizuka, 2015, Bioorganic & medicinal chemistry letters.

Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN.

S. Sasaki, O. Nakagawa, Y. Taniguchi, 2009, Bioorganic & medicinal chemistry letters.

Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes.

F. Nagatsugi, S. Sasaki, Y. Taniguchi, 2006, The Journal of organic chemistry.

Isomerization of Terminal Alkynes Catalyzed by Ytterbium(II)‐Aromatic Imine Complexes.

T. Kitamura, K. Takaki, Y. Makioka, 1997 .

The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition.

S. Sasaki, O. Nakagawa, Genichiro Tsuji, 2010, Chemistry.

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate.

M. Ohno, T. Tsuzuki, Masayuki Yamamoto, 2020, Mutation research.

Modification of the aminopyridine unit of 2′-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences

S. Sasaki, Y. Taniguchi, Lei Wang, 2018, Nucleic acids research.

2,6-diaminopurine nucleoside derivative of 9-ethyloxy-2-oxo-1,3-diazaphenoxazine (2-amino-Adap) for recognition of 8-oxo-dG in DNA.

S. Sasaki, Y. Taniguchi, Yoshiya Kikukawa, 2014, Bioorganic & medicinal chemistry.

Synthesis of 1'-phenyl substituted nucleoside analogs

S. Sasaki, Y. Taniguchi, T. Nasr, 2007 .