S. Natala

Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK).

V. Feher, J. Yano, J. Zalevsky, 2016, Bioorganic & medicinal chemistry letters.

Discovery of TAK-960: an orally available small molecule inhibitor of polo-like kinase 1 (PLK1).

V. Feher, D. Hosfield, T. Kawamoto, 2013, Bioorganic & medicinal chemistry letters.

Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors.

Yan Liu, Jeffrey Stafford, David Hosfield, 2017, Bioorganic & medicinal chemistry letters.

Structure based design and synthesis of novel Toll-like Receptor 2 (TLR 2) lipid antagonists.

R. Abagyan, A. Orry, W. Wrasidlo, 2021, Bioorganic & medicinal chemistry letters.

NPT520-34 improves neuropathology and motor deficits in a transgenic mouse model of Parkinson's disease.

E. Masliah, W. Wrasidlo, D. Bonhaus, 2021, Brain : a journal of neurology.