Beate Heizmann

Syk is a dual-specificity kinase that self-regulates the signal output from the B-cell antigen receptor

M. Reth, S. Infantino, Beate Heizmann, 2010, Proceedings of the National Academy of Sciences.

Ikaros deficiency is associated with aggressive BCR-ABL1 B-cell precursor acute lymphoblastic leukemia independent of the lineage and developmental origin

E. Clappier, H. Cavé, P. Kastner, 2021, Haematologica.

Concurrent CDX2 cis-deregulation and UBTF::ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL

F. Sigaux, J. Soulier, E. Clappier, 2022, Blood.

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

P. Kastner, Susan Chan, Beate Heizmann, 2013, The Journal of experimental medicine.

The Ikaros family in lymphocyte development.

P. Kastner, Susan Chan, Beate Heizmann, 2018, Current opinion in immunology.

Large deletions of the 5′ region of IKZF1 lead to haploinsufficiency in B‐cell precursor acute lymphoblastic leukaemia

H. Cavé, P. Kastner, L. Miguet, 2019, British journal of haematology.

Ikaros antagonizes DNA binding by STAT5 in pre-B cells

P. Kastner, S. Le Gras, Susan Chan, 2020, PloS one.

Ikaros limits follicular B cell activation by regulating B cell receptor signaling pathways.

P. Kastner, Alejandra Macias-Garcia, Susan Chan, 2016, Biochemical and biophysical research communications.

Ikaros Is a Negative Regulator of B1 Cell Development and Function*

Philippe Kastner, P. Kastner, S. Muller, 2016, The Journal of Biological Chemistry.