S. Roberts

发表

Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases

N. LoGiudice, Linh Le, Irene Abuan, 2018, Medical sciences.

The genetic toolbox for Leishmania parasites

S. Roberts, 2011, Bioengineered bugs.

Natural Products That Target the Arginase in Leishmania Parasites Hold Therapeutic Promise

B. Stamper, F. Elbarbry, S. Roberts, 2021, Microorganisms.

Critical functions of the polyamine putrescine for proliferation and viability of Leishmania donovani parasites

John P. Harrelson, N. LoGiudice, S. Roberts, 2019, Amino Acids.

Genetic Manipulation of Leishmania Parasites Facilitates the Exploration of the Polyamine Biosynthetic Pathway as a Potential Therapeutic Target

S. Roberts, 2013 .

Developmentally Regulated Expression of a Novel 59-kDa Product of the Major Surface Protease (Msp or gp63) Gene Family of Leishmania Chagasi(*)

J. Donelson, M. Wilson, S. Roberts, 1995, The Journal of Biological Chemistry.

Generating knock-in parasites: integration of an ornithine decarboxylase transgene into its chromosomal locus in Leishmania donovani.

B. Ullman, Wei Liu, S. Roberts, 2011, Experimental parasitology.

Arginase Is Essential for Survival of Leishmania donovani Promastigotes but Not Intracellular Amastigotes

P. Yates, M. Riscoe, B. Ullman, 2016, Infection and Immunity.

Polyamine Metabolism in Leishmania Parasites: A Promising Therapeutic Target

N. Carter, S. Elikaee, S. Roberts, 2022, Medical sciences.

Spermidine Synthase Is Required for Virulence of Leishmania donovani

B. Ullman, S. Roberts, C. Gilroy, 2011, Infection and Immunity.

Leishmania donovani Ornithine Decarboxylase Is Indispensable for Parasite Survival in the Mammalian Host

M. Wilson, P. Yates, Upasna Gaur, 2008, Infection and Immunity.

Leishmaniasis the Outcome of Murine Cutaneous An Effect of Parasite-Encoded Arginase on Corraliza

M. Wilson, Upasna Gaur, S. Roberts, 2007 .

Arginine Homeostasis and Transport in the Human Pathogen Leishmania donovani*

D. Rentsch, D. Zilberstein, B. Ullman, 2009, The Journal of Biological Chemistry.

Arginase Plays a Pivotal Role in Polyamine Precursor Metabolism in Leishmania

K. Gibson, B. Ullman, S. Roberts, 2004, Journal of Biological Chemistry.

Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infections.

D. Christianson, Y. Hai, M. Wilson, 2013, Archives of biochemistry and biophysics.

Leishmania donovani Polyamine Biosynthetic Enzyme Overproducers as Tools To Investigate the Mode of Action of Cytotoxic Polyamine Analogs

L. Marton, B. Frydman, B. Ullman, 2007, Antimicrobial Agents and Chemotherapy.

S-adenosylmethionine decarboxylase from Leishmania donovani. Molecular, genetic, and biochemical characterization of null mutants and overproducers.

N. Carter, A. Jardim, B. Ullman, 2002, The Journal of biological chemistry.

Identification and Characterization of a Novel Deoxyhypusine Synthase in Leishmania donovani*

R. Madhubala, N. Srinivasan, N. Tyagi, 2009, The Journal of Biological Chemistry.

Polyamine biosynthetic enzymes as drug targets in parasitic protozoa.

B. Ullman, S. Roberts, O. Heby, 2003, Biochemical Society transactions.

Ornithine Decarboxylase Gene Deletion Mutants of Leishmania donovani *

A. Fairlamb, N. Carter, M. Ariyanayagam, 1999, The Journal of Biological Chemistry.

Chapter II Genetic Manipulation of Leishmania Parasites Facilitates the Exploration of the Polyamine Biosynthetic Pathway As a Potential Therapeutic Target

S. Roberts, 2016 .

An Effect of Parasite-Encoded Arginase on the Outcome of Murine Cutaneous Leishmaniasis1

M. Wilson, Upasna Gaur, B. Ullman, 2007, The Journal of Immunology.

Three distinct RNAs for the surface protease gp63 are differentially expressed during development of Leishmania donovani chagasi promastigotes to an infectious form.

J. Donelson, M. Wilson, M. Maybodi, 1992, The Journal of biological chemistry.

Inhibition profile of Leishmania mexicana arginase reveals differences with human arginase I.

B. Ullman, S. Roberts, E. Riley, 2011, International journal for parasitology.

Genetic analysis of spermidine synthase from Leishmania donovani.

N. Carter, A. Jardim, B. Ullman, 2001, Molecular and biochemical parasitology.

A quantitative proteomic screen to identify potential drug resistance mechanism in α-difluoromethylornithine (DFMO) resistant Leishmania donovani.

R. Madhubala, Alok K. Singh, B. Ullman, 2014, Journal of proteomics.

Sequence diversity and organization of the msp gene family encoding gp63 of Leishmania chagasi.

J. Donelson, M. Wilson, R. Ramamoorthy, 1993, Molecular and biochemical parasitology.

Model-based Evaluation of Gene Expression Changes in Response to Leishmania Infection

Julie Tran, B. Stamper, S. Roberts, 2019, Gene regulation and systems biology.

The Polyamine Pathway of Leishmania donovani as a Potential Therapeutic Target

P. Yates, John P. Harrelson, B. Ullman, 2016, The FASEB Journal.

Leishmania donovani Ornithine Decarboxylase Is Indispensable for Parasite Survival in the Mammalian Host

M. Wilson, P. Yates, Upasna Gaur, 2008, Infection and Immunity.

Parasite Polyamines as Pharmaceutical Targets.

B. Ullman, S. Roberts, 2017, Current pharmaceutical design.