S. Klein

发表

Development of high-affinity 5-HT3 receptor antagonists. 2. Two novel tricyclic benzamides.

S. Golec, R. Youssefyeh, R. Woodward, 1992, Journal of medicinal chemistry.

Anti-thrombotic activity of RG13965, a novel platelet fibrinogen receptor antagonist.

C. Dunwiddie, J. Cook, J. Bostwick, 1996, Thrombosis research.

Antithrombotic activity of a linear conformationally flexible RGD mimic

Z. Ruggeri, J. Cook, J. Bostwick, 1993 .

Novel RGD analogs as antithrombotic agents

J. Newman, J. Barrett, Z. Ruggeri, 1991 .

Optimization of the beta-aminoester class of factor Xa inhibitors. Part 1: P(4) and side-chain modifications for improved in vitro potency.

C. Dunwiddie, D. Cheney, A. Spada, 2002, Bioorganic & medicinal chemistry letters.

Constrained β-alanine based GpIIb/IIIa antagonists

S. Klein, V. Chu, B. F. Molino, 1997 .

Antithrombotic efficacy of RPR208566, a novel factor Xa inhibitor, in a rat model of carotid artery thrombosis.

R. Bentley, D. Colussi, J. Bostwick, 2000, European journal of pharmacology.

Superiority of enoxaparin over heparin in combination with a GPIIb/IIIa receptor antagonist during coronary thrombolysis in dogs.

R. Bentley, S. Rebello, J. Bostwick, 2001, Thrombosis research.

Design of a new class of orally active fibrinogen receptor antagonists.

C. Dunwiddie, R. Bentley, J. Bostwick, 1998, Journal of medicinal chemistry.

Conformationally flexible platelet aggregation inhibitors based on the tetrapeptide Arg-Gly-Asp-Arg

S. Klein, V. Chu, B. F. Molino, 1997 .

Non-peptide fibrinogen receptor antagonists based upon a 4-substituted piperidine scaffold

C. Dunwiddie, R. Leadley, S. Klein, 1996 .

Crystal structures of human factor Xa complexed with potent inhibitors.

A. Spada, W. R. Ewing, V. Mikol, 2000, Journal of medicinal chemistry.

Identification and initial structure-activity relationships of a novel class of nonpeptide inhibitors of blood coagulation factor Xa.

D L Cheney, C. Dunwiddie, D. Cheney, 1998, Journal of medicinal chemistry.

Practical routes to two functionalized decalones for the synthesis of quassinoids

U. Pati, J. Kadow, Tein-Fu Wang, 1986 .

Acyclic diastereoselection as a synthetic route to quassinoids: a Claisen rearrangement based strategy for bruceantin

U. Pati, Tein-Fu Wang, S. Klein, 1985 .

Acyclic diastereoselection as a synthetic route to quassinoids: a Claisen rearrangement based strategy for bruceantin

U. Pati, Tein-Fu Wang, S. Klein, 1985 .

Development of high-affinity 5-HT3 receptor antagonists. 1. Initial structure-activity relationship of novel benzamides.

L. Fitzpatrick, C. Pendley, K. Neuenschwander, 1992, Journal of medicinal chemistry.

A novel series of potent and selective small molecule inhibitors of the complement component C1s.

R. DesJarlais, J. Spurlino, C. Illig, 2004, Bioorganic & medicinal chemistry letters.

O-benzyl hydroxyproline as a bioisostere for Phe-Pro: Novel dipeptide thrombin inhibitors

C. Dunwiddie, R. Leadley, S. Klein, 1996 .

Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity.

Daniel L Cheney, C. Dunwiddie, D. Cheney, 2002, Bioorganic & medicinal chemistry letters.