Lutz Tautz

发表

Distinct functional and conformational states of the human lymphoid tyrosine phosphatase catalytic domain can be targeted by choice of the inhibitor chemotype

Caty Chung, Stephan C. Schürer, Dusica Vidovic, 2011, J. Comput. Aided Mol. Des..

Figure 3, Profiling of the 21 most active VHR screening hits at 20 µM against VHR (AID-2074) & HePTP (AID-2082)

Stefan Vasile, Ying Su, Thomas D.Y. Chung, 2010 .

Table 4, Submission of Probe and 5 analogs to the MLSMR

Stefan Vasile, Thomas D.Y. Chung, Eduard Sergienko, 2010 .

Selective HePTP Inhibitors: Probe 1

Thomas D.Y. Chung, Eduard Sergienko, Russell Dahl, 2010 .

Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

Nunzio Bottini, Francesco Cucca, Lutz Tautz, 2005, Nature Genetics.

NMR-based techniques in the hit identification and optimisation processes

Dawoon Jung, Maurizio Pellecchia, Lutz Tautz, 2004, Expert opinion on therapeutic targets.

Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells.

Stefan Vasile, Maurizio Pellecchia, Fabio Cerignoli, 2009, Journal of medicinal chemistry.

In Silico Screening for PTPN22 Inhibitors: Active Hits from an Inactive Phosphatase Conformation

Lutz Tautz, Tomas Mustelin, Shuangding Wu, 2009, ChemMedChem.

Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors.

Kristiina Vuori, Maurizio Pellecchia, Lutz Tautz, 2007, Journal of medicinal chemistry.

Discovery of a novel submicromolar inhibitor of the lymphoid specific tyrosine phosphatase.

Caty Chung, Stephan Schürer, Yuli Xie, 2008, Bioorganic & medicinal chemistry letters.

Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids.

Caty Chung, Stephan C Schürer, Yuli Xie, 2011, Journal of medicinal chemistry.

Covalent decoration of multi-walled carbon nanotubes with silica nanoparticles.

Nunzio Bottini, Stefano Bellucci, Lutz Tautz, 2005, Chemical communications.