T. Iino

发表

Identification of novel and potent 2-amino benzamide derivatives as allosteric glucokinase activators.

K. Kamata, M. Mitsuya, T. Nishimura, 2009, Bioorganic & medicinal chemistry letters.

Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs

J. Berger, A. Kadotani, K. Fujii, 2011, Molecular Pharmacology.

Structure-activity relationships of 3,5-disubstituted benzamides as glucokinase activators with potent in vivo efficacy.

N. Hashimoto, M. Chiba, T. Nishimura, 2009, Bioorganic & medicinal chemistry.

A selective small molecule glucagon-like peptide-1 secretagogue acting via depolarization-coupled Ca(2+) influx.

T. Yada, S. Ito, A. Kanatani, 2009, Journal of Endocrinology.

Nucleosides and Nucleotides. 139. Stereoselective Synthesis of (2′S)-2′-C-Alkyl-2′-deoxyuridines # 1

S. Shuto, A. Matsuda, T. Iino, 1996 .

Metabolic activation of N-thiazol-2-yl benzamide as glucokinase activators: Impacts of glutathione trapping on covalent binding.

N. Hashimoto, M. Chiba, T. Nishimura, 2010, Bioorganic & medicinal chemistry letters.

Discovery of potent and orally active 3-alkoxy-5-phenoxy-N-thiazolyl benzamides as novel allosteric glucokinase activators.

M. Chiba, K. Kamata, T. Nishimura, 2009, Bioorganic & medicinal chemistry.

Nucleosides and nucleotides. 175. Structural requirements of the sugar moiety for the antitumor activities of new nucleoside antimetabolites, 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine and -uracil1.

M. Fukushima, S. Shuto, A. Matsuda, 1998, Journal of medicinal chemistry.

Design of New Types of Antitumor Nucleosides: The Synthesis and Antitumor Activity of 2′-Deoxy-(2′-C-Substituted)Cytidines

N. Minakawa, A. Matsuda, A. Dan, 1993 .

Nucleosides and nucleotides. 134. Synthesis of 2′-C-alkynyl-2′-deoxy-1-β-D-arabinofuranosylpyrimidines via radical deoxygenation of tert-propargyl alcohols in the sugar moiety

A. Matsuda, Y. Yoshimura, T. Iino, 1994 .

Nucleosides and nucleotides. 102. Stereoselective radical deoxygenation of tert-propargyl alcohols in sugar moiety of pyrimidine nucleosides: synthesis of 2′-C-alkynyl-2′-deoxy-1-β-d-arabinofuranosylpyrimidines

A. Matsuda, Y. Yoshimura, T. Iino, 1991 .

Structure-activity relationships of a novel class of endothelin receptor selective antagonists; 6-carboxy-2-isopropylamino-5,7-diarylcyclopenteno[1,2-b]pyridines.

N. Kawanishi, T. Hayama, S. Ozaki, 2004, Bioorganic & medicinal chemistry letters.

Discovery and structure-activity relationships of a novel class of quinazoline glucokinase activators.

M. Chiba, K. Kamata, M. Mitsuya, 2009, Bioorganic & medicinal chemistry letters.

A small-molecule glucokinase activator lowers blood glucose in the sulfonylurea-desensitized rat.

Yun-ping Zhou, Bei B. Zhang, Hiroki Takano, 2010, European journal of pharmacology.