Søren Nielsen

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Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.

Christian M. Metallo, D. Guertin, S. Gujja, 2018, Cell metabolism.

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism

C. Kahn, B. Pedersen, J. Hannukainen, 2018, Nature Metabolism.

Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

C. Schéele, P. Nuutila, N. Petrovic, 2019, Nature Metabolism.

Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution

C. Schéele, M. Schweizer, Y. Tseng, 2021, Cell reports.

obese elderly persons skeletal muscle inflammatory gene expression in frail Exercise but not diet-induced weight loss decreases

B. Pedersen, C. Schéele, D. Cameron-Smith, 2010 .

Human Brown Adipocyte Thermogenesis Is Driven by β2-AR Stimulation.

C. Schéele, A. Carpentier, F. Haman, 2020, Cell metabolism.

Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity

Shujiro Okuda, C. Schéele, T. Minamino, 2022, iScience.

Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity.

T. Soga, C. Schéele, T. Minamino, 2018, Cell reports.

Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat

B. Emanuelli, C. Schéele, Naja Jespersen, 2020, Frontiers in Endocrinology.

Fibroblast Growth Factor-21 Is Induced in Human Skeletal Muscles by Hyperinsulinemia

B. Pedersen, R. Krogh‐Madsen, A. Nielsen, 2009, Diabetes.

ROS and myokines promote muscle adaptation to exercise

B. Pedersen, C. Schéele, Søren Nielsen, 2009, Trends in Endocrinology & Metabolism.

Novel nuances of human brown fat

C. Schéele, Søren Nielsen, T. J. Larsen, 2014, Adipocyte.

Human visceral and subcutaneous adipose stem and progenitor cells retain depot-specific adipogenic properties during obesity

B. Pedersen, C. Schéele, M. Watt, 2022, Frontiers in Cell and Developmental Biology.

Cold-induced expression of a truncated Adenylyl Cyclase 3 acts as rheostat to brown fat function

T. Schulz, Á. Rada-Iglesias, Rizwan Rehimi, 2022, bioRxiv.

Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells

Lawrence M. Lifshitz, R. Maehr, M. Garber, 2019, Proceedings of the National Academy of Sciences.

Purification of mitochondria from skeletal muscle tissue for transcriptomic analyses reveals localisation of nuclear-encoded non-coding RNAs

S. Lamon, G. Wadley, M. Ziemann, 2024, bioRxiv.

Thermogenic genes are blunted whereas brown adipose tissue identity is preserved in human obesity

S. Mandrup, B. Pedersen, C. Schéele, 2020, bioRxiv.

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine.

M. Mann, D. Drucker, C. H. Nielsen, 2019, Cell metabolism.

Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473

B. Emanuelli, H. Willenbrock, B. Pedersen, 2020, Nature metabolism.

A long-non-coding RNA, LINC00473, confers the human adipose tissue thermogenic phenotype through enhanced cAMP responsiveness

H. Willenbrock, B. Pedersen, Tiffany DeSouza, 2018, bioRxiv.

The obesity-linked human lncRNA AATBC regulates adipocyte plasticity by stimulating mitochondrial dynamics and respiration

S. Herzig, M. Blüher, P. Fischer-Posovszky, 2021 .

Heterogeneity in the perirenal region of humans suggests presence of dormant brown adipose tissue that contains brown fat precursor cells

B. Pedersen, C. Schéele, N. S. Hansen, 2019, Molecular metabolism.

Asymmetric perirenal brown adipose dormancy in adult humans is defined by local sympathetic activity

B. Pedersen, C. Schéele, N. S. Hansen, 2018, bioRxiv.

Metabolic regulation and the anti-obesity perspectives of human brown fat

C. Schéele, Søren Nielsen, 2017, Redox biology.

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Xianlin Han, T. Hansen, O. Pedersen, 2018, Cell metabolism.

Dysregulation of a novel miR-23b/27b-p53 axis impairs muscle stem cell differentiation of humans with type 2 diabetes

Peter K. Davidsen, A. Vaag, B. Pedersen, 2017, Molecular metabolism.

Human thermogenic adipocyte regulation by the long noncoding RNA LINC00473

B. Emanuelli, H. Willenbrock, B. Pedersen, 2020, Nature Metabolism.

Human brown adipose tissue is phenocopied by classical brown adipose tissue in physiologically humanized mice

C. Schéele, P. Nuutila, N. Petrovic, 2019, Nature Metabolism.

Proteomics-based comparative mapping of the human brown and white adipocyte secretome reveals EPDR1 as a novel batokine

M. Mann, B. Holst, B. Pedersen, 2018, bioRxiv.

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

T. Hansen, O. Pedersen, N. Grarup, 2021, Cell.

Temporal trajectories of human brown and white adipocyte progenitors at single cell resolution

Alexander G. B. Grønning, Nagendra P. Palani, T. Pers, 2022 .

TGF-β2 is an exercise-induced adipokine that regulates glucose and fatty acid metabolism

J. Hannukainen, P. Nuutila, P. Nigro, 2019, Nature Metabolism.

Adipogenic and SWAT cells separate from a common progenitor in human brown and white adipose depots

Alexander G. B. Grønning, Nagendra P. Palani, T. Pers, 2023, Nature Metabolism.

Full activation of thermogenesis in brown adipocytes requires Basigin action

B. Emanuelli, J. Hansen, T. Moritz, 2023, The FEBS journal.

Can we target obesity using a single-cell atlas of adipose tissue?

C. Schéele, Søren Nielsen, 2022, Med.

Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis.

Christian M. Metallo, D. Guertin, C. Schéele, 2018, Cell metabolism.

The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes

S. Herzig, P. Fischer-Posovszky, M. Scheideler, 2023, EMBO reports.