R. Ward

发表

Identification of a series of 1,3,4-oxadiazol-2-amines as potent alpha-7 agonists with efficacy in the novel object recognition model of cognition.

David M. Wilson, D. Pemberton, Frank T. Coppo, 2012, Bioorganic & medicinal chemistry letters.

6-heteroaryl-pyrazolo[3,4-b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

A. Naylor, A. Takle, J. Witherington, 2003, Bioorganic & medicinal chemistry letters.

Aryl sulphonyl amides as potent agonists of the growth hormone secretagogue (ghrelin) receptor.

A. Muir, Benjamin R Bellenie, G. Sanger, 2009, Bioorganic & medicinal chemistry letters.

Aminophosphonic acid containing inhibitors of human collagenase: modification of the P1 residue

E. Karran, J. Bird, R. Markwell, 1994 .

Pyridone derivatives as potent and selective VLA-4 integrin antagonists.

N. Parr, A. Naylor, A. Takle, 2006, Bioorganic & medicinal chemistry letters.

A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor

N. Kotecha, H. Chapman, L. Beeley, 1997 .

7-Aroyl-2,3-dihydrobenzo[b]furan-3-carboxylic acids and 7-benzoyl-2,3-dihydrobenzo[b]thiophene-3-carboxylic acids as analgesic agents.

P. Wyman, S. Smith, R. Markwell, 1986, Journal of medicinal chemistry.

Synthesis of novel N-phosphonoalkyl dipeptide inhibitors of human collagenase.

E. Karran, J. Bird, S. Rahman, 1994, Journal of medicinal chemistry.

7-Aroyl-2,3-dihydrobenzo[b]furan-3-carboxylic Acids and 7-Benzoyl-2,3- dihydrobenzo[b]thiophene-3-carboxylic Acids as Analgesic Agents.

P. Wyman, Stephen A. Smith, R. Markwell, 1986 .

The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives.

R. Ife, D. Haigh, D. G. Smith, 1999, Bioorganic & medicinal chemistry letters.

Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase.

D. Matthews, C. Janson, K. Appelt, 1996, Journal of medicinal chemistry.

Novel products arising from bisarylmaleimide synthesis

R. Copley, N. Garton, R. Ward, 2008 .

Synthesis of Novel N‐Phosphonoalkyl Dipeptide Inhibitors of Human Collagenase.

E. Karran, J. Bird, S. Rahman, 2010 .

Inhibitors of human collagenase: dipeptide mimetics with lactam and azalactam moieties at the P2′P3′ position

E. Karran, J. Bird, S. Rahman, 1995 .

The synthesis of pyrazolo[4,3-c]- and imidazo[4,5-c]-Aryl[e]fused pyridines as structural analogues of 4-aminonicotinoates

T. Blackburn, N. Kotecha, C. Benham, 1995 .

Isosteric replacement of the indole nucleus by benzothiophene in a series of pyrido[2,3-b]indoles with potential anxiolytic activity

D. Davies, I. Forbes, T. Blackburn, 1995 .

Steric acceleration of an uncatalysed ene reaction at room temperature.

P. G. Sammes, R. Ward, G. Smith, 2001, Chemical communications.

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

M. Saunders, R. Ife, D. Haigh, 2001, Bioorganic & medicinal chemistry letters.

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.

J W Yates, A. Reith, J. Holder, 2000, Chemistry & biology.

4,5,8,9-tetrahydro-8-methyl-9-oxothieno[3′,2′:5,6]cyclohepta[1,2-b]- pyrrole-7-acetic acid. A new anti-inflammatory/analgesic agent

R. Ward, A. C. Goudie, H. E. Rosenberg, 1983 .

5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

M. Saunders, J. Liddle, S. Garland, 2003, Bioorganic & medicinal chemistry letters.

Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists.

A. Naylor, A. Takle, J. Witherington, 2006, Bioorganic & medicinal chemistry letters.

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

R. Ife, D. M. Hickey, D. Haigh, 2003, Bioorganic & medicinal chemistry letters.

Potent oxadiazole CGRP receptor antagonists for the potential treatment of migraine.

Michael A. Briggs, David M. Wilson, I. Wall, 2010, Bioorganic & medicinal chemistry letters.

6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

A. Naylor, A. Takle, J. Witherington, 2003, Bioorganic & Medicinal Chemistry Letters.

Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.

D. Matthews, C. Janson, R. Bacquet, 1997, Journal of medicinal chemistry.

On the steric acceleration of ene reactions

N. Kuhnert, R. Ward, Graham F. Smith, 2002 .