Mark S. Lee

发表

A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ.

C. R. Glassman, A. Ting, C. Uttamapinant, 2015, Immunity.

Domain-swapped T cell receptors improve the safety of TCR gene therapy

J. Heath, D. Baltimore, W. Uckert, 2016, eLife.

A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells

T. Serwold, M. Niewczas, M. A. Thelin, 2020, Proceedings of the National Academy of Sciences.

Enhancing and inhibitory motifs regulate CD4 activity

Mark S. Lee, Heather L. Parrish, M. S. Kuhns, 2022, eLife.

A Mechanical Switch Coup les T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD 3 zz Graphical

C. R. Glassman, A. Ting, C. Uttamapinant, 2022 .

Enhancing and inhibitory motifs have coevolved to regulate CD4 activity

K. Doorslaer, Mark S. Lee, Heather L. Parrish, 2021, bioRxiv.

Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex

Mark S. Lee, Heather L. Parrish, C. Glassman, 2018, Cell reports.

The CD4 transmembrane GGXXG and juxtamembrane (C/F)CV+C motifs mediate pMHCII-specific signaling independently of CD4-Lck interactions

K. Doorslaer, Mark S. Lee, Heather L. Parrish, 2023, bioRxiv.

Bonds Voyage! A Dissociative Model of TCR-CD3 Triggering Is Proposed.

Mark S. Lee, Katrina Lichauco, M. Kuhns, 2018, Immunity.