Seema Tevar

发表

Discovery of orally bioavailable imidazo[1,2-a]pyrazine-based Aurora kinase inhibitors.

Patrick J. Curran, M. Williams, Ming Liu, 2010, Bioorganic & medicinal chemistry letters.

Aurora kinase inhibitors based on the imidazo[1,2-a]pyrazine core: fluorine and deuterium incorporation improve oral absorption and exposure.

Ming Liu, R. Doll, A. Basso, 2011, Journal of medicinal chemistry.

SCH 2047069, a Novel Oral Kinesin Spindle Protein Inhibitor, Shows Single-Agent Antitumor Activity and Enhances the Efficacy of Chemotherapeutics

D. Hicklin, P. Kirschmeier, Ming Liu, 2010 .

SCH 2047069, a Novel Oral Kinesin Spindle Protein Inhibitor, Shows Single-Agent Antitumor Activity and Enhances the Efficacy of Chemotherapeutics

D. Hicklin, P. Kirschmeier, Ming Liu, 2010, Molecular Cancer Therapeutics.

SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors

F. Monsma, D. Hicklin, P. Kirschmeier, 2011, Cancer Chemotherapy and Pharmacology.

ProBDNF Induces Neuronal Apoptosis via Activation of a Receptor Complex of p75NTR and Sortilin

Barbara L. Hempstead, Ramiro D. Almeida, F. Lee, 2005, The Journal of Neuroscience.

SCH 2047069, a Novel Oral Kinesin Spindle Protein Inhibitor, Shows Single-Agent Antitumor Activity and Enhances the Efficacy of Chemotherapeutics

D. Hicklin, P. Kirschmeier, Ming Liu, 2010, Molecular Cancer Therapeutics.

Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.

Patrick J. Curran, Ming Liu, R. Doll, 2010, ACS medicinal chemistry letters.

SCH 2047069, a Novel Oral Kinesin Spindle Protein Inhibitor, Shows Single-Agent Antitumor Activity and Enhances the Efficacy of Chemotherapeutics

D. Hicklin, P. Kirschmeier, Ming Liu, 2010 .

Bioisosteric approach to the discovery of imidazo[1,2-a]pyrazines as potent Aurora kinase inhibitors.

B. Kulkarni, R. Doll, A. Basso, 2011, Bioorganic & medicinal chemistry letters.

SCH 2047069, a Novel Oral Kinesin Spindle Protein Inhibitor, Shows Single-Agent Antitumor Activity and Enhances the Efficacy of Chemotherapeutics

D. Hicklin, P. Kirschmeier, Ming Liu, 2010, Molecular Cancer Therapeutics.