M. Sutherland

发表

Sclerostin promotes the apoptosis of human osteoblastic cells: a novel regulation of bone formation.

J. Latham, E. Turcott, James C. Geoghegan, 2004, Bone.

Reply: CD133 expression in different stages of gastric adenocarcinoma

P. Carter, P. Moore, S. Ruben, 2009, British Journal of Cancer.

Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates*

Damon L. Meyer, A. Wahl, T. Lewis, 2006, Journal of Biological Chemistry.

Aluminum-binding serum proteins: desferrioxamine alters serum aluminum speciation.

C. Mizzen, D. McLachlan, T. Kruck, 1992, Clinica chimica acta; international journal of clinical chemistry.

Abstract DDT02-04: SGN-CD33A: Preclinical and phase 1 interim clinical trial results of a CD33-directed PBD dimer antibody-drug conjugate for the treatment of acute myeloid leukemia (AML)

E. Feldman, S. Alley, M. O'Meara, 2015 .

A sugar engineered non-fucosylated anti-CD40 antibody, SEA-CD40, with enhanced immune stimulatory activity alone and in combination with immune checkpoint inhibitors.

S. Peng, J. Drachman, Haley D Neff-Laford, 2015 .

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody–Drug Conjugate for Acute Myeloid Leukemia

John F. Valliere-Douglass, T. Lewis, Sa A. Wang, 2017, Molecular Cancer Therapeutics.

Unique regulation of SOST, the sclerosteosis gene, by BMPs and steroid hormones in human osteoblasts.

J. Latham, James C. Geoghegan, D. Winkler, 2004, Bone.

Sclerostin Inhibition of Wnt-3a-induced C3H10T1/2 Cell Differentiation Is Indirect and Mediated by Bone Morphogenetic Proteins*

J. Latham, E. Turcott, James C. Geoghegan, 2005, Journal of Biological Chemistry.

Noggin and Sclerostin Bone Morphogenetic Protein Antagonists Form a Mutually Inhibitory Complex*

J. Latham, James C. Geoghegan, D. Winkler, 2004, Journal of Biological Chemistry.

5-Azacytidine enhances the anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

N. Van Rooijen, Martha E. Anderson, C. Law, 2010, mAbs.

Cancer Therapy : Preclinical Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NKCellResistance in MLL-RearrangedLeukemiaExpressing Inhibitory KIR Ligands but not Activating Ligands

J. Zalevsky, W. Leung, W. Chan, 2012 .

The biological activities of 1alpha,25-dihydroxyvitamin D3 and its synthetic analog 1alpha,25-dihydroxy-16-ene-vitamin D3 in normal human osteoblastic cells and human osteosarcoma SaOS-2 cells are modulated by 17-beta estradiol and dependent on stage of differentiation.

R. McBroom, M. Uskoković, L. Rao, 2001, Biological & pharmaceutical bulletin.

Effects of 1α,25-dihydroxy-16ene, 23yne-vitamin D3 on osteoblastic function in human osteosarcoma SaOS-2 cells: differentiation-stage dependence and modulation by 17-β estradiol

M. Uskoković, L. Rao, G. Reddy, 1996 .

SGN-33 Modulates Cytokine and Chemokine Production by Activated Monocytes and Macrophages.

T. Lewis, J. Drachman, C. Law, 2006 .

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist

John A Latham, K. Staehling-Hampton, M. Brunkow, 2003, The EMBO journal.

Impairment of systemic concomitant antitumor immunity by excess soluble tumor antigen

J. Proctor, D. Thomson, M. Sutherland, 1980, Cancer Immunology, Immunotherapy.

Reduction of vitamin D hormone receptor mRNA levels in Alzheimer as compared to Huntington hippocampus: correlation with calbindin-28k mRNA levels.

M. Somerville, M. Haussler, C. Bergeron, 1992, Brain research. Molecular brain research.

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

P. Carter, P. Moore, S. Ruben, 2008, British Journal of Cancer.

A correlation between gene transcriptional activity and cerebral glucose metabolism in Alzheimer's disease-affected neocortex: cause or effect?

W. Lukiw, D. McLachlan, P. Handley, 1991, Advances in experimental medicine and biology.

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody–drug conjugate SGN-75

A. Nesterova, S. Duniho, C. Law, 2010, British Journal of Cancer.

SGN-CD123A, a Pyrrolobenzodiazepine Dimer Linked Anti-CD123 Antibody Drug Conjugate, Demonstrates Effective Anti-Leukemic Activity in Multiple Preclinical Models of AML

John F. Valliere-Douglass, R. Walter, D. Benjamin, 2015 .

SGN-CD33A in Combination with Hypomethylating Agents Is Highly Efficacious in Preclinical Models of AML

D. Benjamin, E. Feldman, S. Alley, 2015 .

Anti-leukemic activity of Lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia

A. Nesterova, T. Lewis, H. Gerber, 2009, mAbs.

The Humanized Anti-CD40 Monoclonal Antibody, SGN-40, Potentiates Chemotherapy Regimens in NHL Xenograft Models Via Pro-Apoptotic Signaling.

T. Lewis, H. Gerber, J. Drachman, 2007 .

SGN-CD33A: A Novel CD33-Directed Antibody-Drug Conjugate, Utilizing Pyrrolobenzodiazepine Dimers, Demonstrates Preclinical Antitumor Activity Against Multi-Drug Resistant Human AML

I. Bernstein, P. Burke, R. Walter, 2012 .

Reduction of thyroid hormone receptor c-ERB Aα mRNA levels in the hippocampus of Alzheimer as compared to huntington brain

M. Somerville, P. Handley, L. Wong, 1992, Neurobiology of Aging.

Effects of SP500263, a novel, potent antiestrogen, on breast cancer cells and in xenograft models.

David W. Anderson, S. Bhagwat, E. O'leary, 2002, Cancer research.

Carboxyl‐terminal parathyroid hormone peptide (53–84) elevates alkaline phosphatase and osteocalcin mRNA levels in SaOS‐2 cells

J. Wylie, J. Sodek, Ashwani K. Gupta, 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Reduction of calbindin-28k mRNA levels in Alzheimer as compared to Huntington hippocampus.

M. Somerville, M. Parmentier, C. Bergeron, 1993, Brain research. Molecular brain research.

Long-term culture in dexamethasone unmasks an abnormal phenotype in osteoblasts isolated from osteoporotic subjects

J. Wylie, T. Murray, M. Sutherland, 2005, Journal of endocrinological investigation.

Immunohistochemical localization of the estrogen receptor in human osteoblastic SaOS-2 cells: association of receptor levels with alkaline phosphatase activity.

L. Rao, J. Wylie, T. Murray, 1996, Bone.

The Humanized Anti-CD40 Antibody, SGN-40, Promotes Apoptosis Signaling and Is Effective in Combination with Standard Therapies in Lymphoma Xenograft Models.

A. Wahl, T. Lewis, J. Drachman, 2006 .

SGN-35, an Anti-CD30 Antibody-Drug Conjugate, Exhibits Potent Antitumor Activity for the Treatment of CD30+ Malignancies.

A. Wahl, Michael M C Sun, C. Cerveny, 2005 .