O. Moukha-Chafiq

发表

Structure-activity relationship for adenosine kinase from Mycobacterium tuberculosis II. Modifications to the ribofuranosyl moiety.

W. Parker, Lisa A Nagy, S. Shaddix, 2008, Biochemical pharmacology.

Identification of DOT1L inhibitors by structure-based virtual screening adapted from a nucleoside-focused library.

Y. Dou, Z. Nikolovska-Coleska, Chenzhong Liao, 2020, European journal of medicinal chemistry.

Unique Functional and Structural Properties of the LRRK2 Protein ATP-binding Pocket*

L. DeLucas, A. West, E. White, 2014, The Journal of Biological Chemistry.

The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition

A. West, R. Boddu, Kaela Kelly, 2018, Experimental Neurology.

Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action.

P. Sethupathy, A. Shalev, Jason K. Kim, 2020, Cell metabolism.

Parallel Solution-Phase Synthesis and General Biological Activity of a Uridine Antibiotic Analog Library

R. Reynolds, O. Moukha-Chafiq, 2014, ACS combinatorial science.

SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice

C. Zhan, S. Ananthan, T. Cirino, 2022, Neuropharmacology.

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME ACYCLIC α-(1H-PYRAZOLO[3,4-d]PYRIMIDIN-4-YL)THIOALKYLAMIDE NUCLEOSIDES

E. De Clercq, J. Vasseur, H. Lazrek, 2002, Nucleosides, nucleotides & nucleic acids.

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 4-SUBSTITUTED 1-[1-(2-HYDROXYETHOXY)- METHYL-1,2,3-TRIAZOL-(4 & 5)-YLMETHYL]-1H-PYRAZOLO[3,4-d]PYRIMIDINES

E. De Clercq, C. Pannecouque, M. Witvrouw, 2001, Nucleosides, nucleotides & nucleic acids.

SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME 4-SUBSTITUTED 1-[1-(4-HYDROXYBUTYL)-1,2,3-TRIAZOL-(4 & 5)-YLMETHYL]-1H-PYRAZOLO-[3,4-d]PYRIMIDINES

E. De Clercq, C. Pannecouque, M. Witvrouw, 2001, Nucleosides, nucleotides & nucleic acids.

Inhibitors of HIV-1 Nef-Mediated Activation of the Myeloid Src-Family Kinase Hck Block HIV-1 Replication in Macrophages and Disrupt MHC-I Downregulation.

R. Ptak, S. Du, T. Smithgall, 2022, ACS infectious diseases.

Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.

Nichole A. Tower, M. Heise, B. Tekwani, 2021, Journal of medicinal chemistry.

Parallel Solution Phase Synthesis and Preliminary Biological Activity of a 5'-Substituted Cytidine Analog Library.

R. Reynolds, O. Moukha-Chafiq, T. Snowden, 2019, ACS combinatorial science.

Synthesis and biological activity of some 4-substituted 1-[1-(2,3-dihydroxy-1-propoxy)methyl-1,2,3-triazol-(4 & 5)-ylmethyl]-1H-pyrazolo[3,4-d]pyrimidines.

Myriam Witvrouw, Jean-Jacques Vasseur, Christophe Pannecouque, 2002, Farmaco.

Synthesis and General Biological Activity of a Small Adenosine-5′-(Carboxamide and Sulfanilamide) Library

R. Reynolds, O. Moukha-Chafiq, 2014, Nucleosides, nucleotides & nucleic acids.

Synthesis of Novel Peptidyl Adenosine Antibiotic Analogs

R. Reynolds, O. Moukha-Chafiq, 2014, Nucleosides, nucleotides & nucleic acids.

Parallel solution-phase synthesis of an adenosine antibiotic analog library.

R. Reynolds, O. Moukha-Chafiq, 2013, ACS combinatorial science.

Synthesis and Biological Evaluation of Some Acyclic 4,6-Disubstituted 1H-Pyrazolo[3,4-d]pyrimidine Nucleosides

E. De Clercq, J. Vasseur, H. Lazrek, 2003, Nucleosides, nucleotides & nucleic acids.

Synthesis and Antiviral Activity of Some C2-, C4-, and C6-Substituted Pyrazolo[3,4-D]Pyrimidine Acyclonucleosides with the Alkylating Chains of ACV, HBG, and ISO-DHPG

E. Clercq, J. Vasseur, H. Lazrek, 2006, Nucleosides, nucleotides & nucleic acids.

Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus

M. Heise, R. Bostwick, Nathaniel J. Moorman, 2021, Antimicrobial agents and chemotherapy.

Synthesis and Biological Evaluation of Some α-[6-(1′-Carbamoylalkylthio)-1 H-Pyrazolo[3,4-D]Pyrimidin-4-yl]Thioalkylcarboxamide Acyclonucleosides

E. Clercq, J. Vasseur, H. Lazrek, 2007, Nucleosides, nucleotides & nucleic acids.

SYNTHESIS OF SOME ACYCLONUCLEOSIDES α-(PYRAZOLO[3,4-d]PYRIMIDIN-4-YLTHIO)-ALKYLAMIDES

J. Imbach, J. Vasseur, H. Lazrek, 2001, Nucleosides, nucleotides & nucleic acids.

SYNTHESIS OF SOME 2′-FLUORO-2′-DEOXY-3′-C-ETHYNYL AND 3′-C-VINYL-β-D-LYXOFURANOSYL NUCLEOSIDES

J. Secrist, K. Tiwari, O. Moukha-Chafiq, 2005, Nucleosides, nucleotides & nucleic acids.

Synthesis and Anti-HSV Activity of new N1-Acyclic C4 and C6-Disubstituted Pyrazolo[3,4-D]Pyrimidine Nucleosides

O. Moukha-Chafiq, M. Taha, A. Mouna, 2007, Nucleosides, nucleotides & nucleic acids.

Identification of quinazoline compounds as novel potent inhibitors of Wnt/β-catenin signaling in colorectal cancer cells

Yonghe Li, Wenyan Lu, S. Ananthan, 2016, Oncotarget.

A limb-girdle muscular dystrophy 2I model of muscular dystrophy identifies corrective drug compounds for dystroglycanopathies.

L. Kunkel, J. Widrick, A. Lek, 2018, JCI insight.

Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists

J. Streicher, C. Augelli-Szafran, Parthasaradhireddy Tanguturi, 2021, Molecules.

Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. Molecules 2021, 26, 6693

J. Streicher, Parthasaradhireddy Tanguturi, V. Pathak, 2022, Molecules.

The D3 receptor antagonist SR 21502 reduces cue-induced reinstatement of methamphetamine-seeking in rats

J. Streicher, R. Ranaldi, C. Augelli-Szafran, 2023, Neuroscience Letters.