R. Duthaler

发表

Removal of anti-Galalpha1,3Gal xenoantibodies with an injectable polymer.

E. Persohn, M. Streiff, G. Thoma, 2002, The Journal of clinical investigation.

Removal of anti-Galα1,3Gal xenoantibodies with an injectable polymer

E. Persohn, M. Streiff, G. Thoma, 2002 .

Nanomolar E-selectin inhibitors: 700-fold potentiation of affinity by multivalent ligand presentation.

G. Thoma, J. Patton, J. Magnani, 2001, Journal of the American Chemical Society.

Versatile Functionalization of Polylysine: Synthesis, Characterization, and Use of Neoglycoconjugates

B. Ernst, G. Thoma, J. Patton, 1999 .

Steric and electronic effects on nitrogen-15 chemical shifts of saturated aliphatic amines and their hydrochlorides

John D. Roberts, R. Duthaler, J. Roberts, 1978 .

Novel glycodendrimers self-assemble to nanoparticles which function as polyvalent ligands in vitro and in vivo.

N. Voelcker, M. Streiff, G. Thoma, 2002, Angewandte Chemie.

Synthesis of Gal determinant epitopes, their glycomimetic variants, and trimeric clusters—relevance to tumor associated antigens and to discordant xenografts

M. Streiff, S. Hanessian, R. Oehrlein, 2001 .

Synthesis and characterization of polyaspartic acid-carbohydrate conjugates: Multivalent sialyl lewis

B. Ernst, G. Thoma, R. Duthaler, 1997 .

Synthesis of Ethyl (2RS,3SR)‐1‐Tosyl‐3‐Vinylazetidine‐2‐carboxylate and ethyl (2RS,E)‐3‐ethylidene‐1‐tosylazetidine‐2‐carboxylate (=rac‐ethyl N‐tosylpolyximate)

R. Duthaler, H. Bauman, 1988 .

Preparation of 3‐Oxo‐ and 3‐Ethylideneazetidine Derivatives

R. Duthaler, H. Bauman, 1988 .

Depletion of anti‐Gal antibodies by the intravenous infusion of Gal type 2 and 6 glycoconjugates in baboons

D. Sachs, L. Bühler, D. Cooper, 2003, Xenotransplantation.

Neutralization of anti-alphaGalactosyl antibodies without immunosuppression prevents hyperacute rejection but not acute vascular rejection of pig organs transplanted into baboons.

R. Oehrlein, R. Mañez, A. Katopodis, 2000, Transplantation proceedings.

Reduction of anti‐Galα1,3Gal antibodies by infusion of types 2 and 6 gal trisaccharides conjugated to poly‐l‐lysine

K. Kuwaki, D. Cooper, H. Schuurman, 2004 .

Improvement in human decay accelerating factor transgenic porcine kidney xenograft rejection with intravenous administration of gas914, a polymeric form of &agr;gal1

S. Chakrabarti, Yigang Luo, A. Jevnikar, 2003, Transplantation.

Bull. Soc. Chim. Fr.

Anthony B. Pinkerton, Michael Wörle, Reinhard Nesper, 1957 .

Electrophilic Fluorinations with N-Fluorobenzenesulfonimide: Convenient Access to α-Fluoro- and α,α-Difluorophosphonates

R. Duthaler, E. Differding, G. M. Rüegg, 1991 .

Proline-Catalyzed Asymmetric α-Amination of Aldehydes and Ketones—An Astonishingly Simple Access to Optically Active α-Hydrazino Carbonyl Compounds

R. Duthaler, 2003 .

Recent developments in the stereoselective synthesis of α-aminoacids

R. Duthaler, 1994 .

A facile synthesis of optically pure (−)-(S)-ipsenol using a chiral titanium complex

R. Duthaler, K. Oertle, E. Steiner, 1990 .

Enantioselective Allylation of Carbonyl Compounds with Titanium‐Carbohydrate Complexes

R. Duthaler, M. Riediker, 1989 .

Enantioselective Aldol Reaction of tert-Butyl Acetate using Titanium-Carbohydrate Complexes†

P. Herold, R. Duthaler, K. Oertle, 1989 .

Enantioselective Synthesis of D‐threo‐β‐Hydroxy‐α‐amino Acids with Titanium‐Carbohydrate Complexes

G. Bold, R. Duthaler, M. Riediker, 1989 .

Enantioselective syntheses with titanium carbohydrate complexes. Part 7. Enantioselective allyltitanation of aldehydes with cyclopentadienyldialkoxyallyltitanium complexes

R. Marti, A. Hafner, G. Rihs, 1992 .

Fluorotitanium Compounds—Novel Catalysts for the Addition of Nucleophiles to Aldehydes

A. Hafner, R. Duthaler, 1997 .

Enantio‐ and Diastereoselective Aldol‐Reaction of 2,6‐Dimethylphenyl Propionate Using Titanium‐Carbohydrate Complexes

P. Herold, R. Duthaler, M. Riediker, 1990 .

Chiral Titanium Complexes for Enantioselective Addition of Nucleophiles to Carbonyl Groups

A. Hafner, R. Duthaler, 1992 .

Experiments on the total synthesis of Lysolipin I. Part II. Michael addition of 1,3-cyclohexanedione to quinone acetals†‡

U. Wegmann, R. Duthaler, 1984 .

Proline-catalyzed asymmetric alpha-amination of aldehydes and ketones--an astonishingly simple access to optically active alpha-hydrazino carbonyl compounds.

R. Duthaler, 2003, Angewandte Chemie.

Preparation of Bicyclo[3.3.0]octane‐2,8‐dione‐ and Declain‐1,8‐dione‐Derivatives

P. Maienfisch, R. Duthaler, 1984 .

Stereoselective transformations mediated by chiral titanium complexes

A. Hafner, R. Duthaler, 1996 .

Synthesis of Optically Pure Compounds by Enantiotopically Differentiating Monoacetalization of Prochiral Diketones. Part II. Fragmentation of β‐Keto‐Acetals

P. Maienfisch, R. Duthaler, 1984 .

Synthesis of optically pure compounds by enantiotopically differentiating monoacetalization of prochiral diketones

P. Maienfisch, R. Duthaler, 1982 .

Stereoselective transformations mediated by chiral monocyclo-pentadienyl titanium, zirconium, and hafnium complexes

A. Hafner, P. Alsters, G. Rihs, 1992 .

The preparation of chiral titanium reagents: a comparison of new and known ligands

G. Bold, A. Hafner, P. Alsters, 1994 .

Asymmetric C-C bond formation with titanium carbohydrate complexes

A. Hafner, R. Duthaler, M. Riediker, 1990 .

Chloro(η5‐cyclopentadienyl)[(4R,trans)‐2,2‐dimethyl‐α,α,α′,α′‐tetraphenyl‐1,3‐dioxolane‐4,5‐dimethanolato(2−)‐Oα,Oα′]titanium

A. Hafner, R. Duthaler, 2001 .

Conversion of L-Cysteine into D-α-Amino Acids and Related Transformations

R. Duthaler, Bernhard Wyss, 2011 .

Synthese von β,γ‐ungesättigten D‐α‐Aminosäuren aus L‐Cystein

R. Duthaler, 1991 .

Synthesis of Oligosaccharide-Polylysine Conjugates: A Well Characterized Sialyl Lewisa Polymer for ELISA

B. Ernst, G. Thoma, J. Magnani, 1997 .

Synthesis of β,γ‐Unsaturated D‐α‐Amino Acids from L‐Cysteine

R. Duthaler, 1991 .

Construction of Highly Substituted Nitroaromatic Systems by Cyclocondensation. Part I. Synthesis of 4‐nitro‐3‐oxobutyrate

R. Duthaler, 1983 .

Construction of Highly Substituted Nitroaromatic Systems by Cyclocondensation. Part II. Conversion of 4‐nitro‐3‐oxobutyrate to 3‐nitrosalicylates

R. Duthaler, 1983 .

PB20 SYNTHESIS OF D-erythro- AND D-threo-SPHINGOSINE DERIVATIVES FROM L-SERINE

P. Herold, R. Duthaler, 1988 .

Synthesis of a Sialyl Lewis x Mimic with Fixed Carboxylic Acid Group: Chemical Approach toward the Elucidation of the Bioactive Conformation of Sialyl Lewis x.

G. Thoma, R. Duthaler, F. Schwarzenbach, 1996, The Journal of organic chemistry.

Trichloro(cyclopentadienyl)titanium

A. Hafner, R. Duthaler, 2001 .

Enantioselective Syntheses with Titanium Carbohydrate Complexes. Part 6. Enantioselective Allyltitanation of Aldehydes with Cyclopentadienyldialkoxyallyltitanium Complexes.

R. Marti, A. Hafner, G. Rihs, 1992 .

Preparation of Regioselectively Protected Hydroquinones by Phosphorylation of p‐Benzoquinones with Trialkyl Phosphites

R. Duthaler, P. Lyle, C. Heuberger, 1984 .

Natural-abundance nitrogen-15 nuclear magnetic resonance spectroscopy. Steric and electronic effects on nitrogen-15 chemical shifts of piperidines and decahydroquinolines

John D. Roberts, D. D. Giannini, R. Duthaler, 1977 .

Synthesis of optically pure compounds by enantiotopically differentiating monoacetalization of prochiral diketones

P. Maienfisch, R. Duthaler, 1982 .

Nitrogen-15 Nuclear Magnetic Resonance Spectroscopy. Solvent Effects on the ^(15)N Chemical Shifts of Saturated Amines and their Hydrochlorides

R. Duthaler, J. Roberts, 1979 .

Steric and electronic effects on nitrogen-15 chemical shifts of piperidine and decahydroquinoline hydrochlorides

J. Roberts, R. Duthaler, 1978 .

Synthesis of a Sialyl Lewis x Mimic with Fixed Carboxylic Acid Group: Chemical Approach toward the Elucidation of the Bioactive Conformation of Sialyl Lewis x.

G. Thoma, R. Duthaler, F. Schwarzenbach, 1996, The Journal of organic chemistry.

Effects of solvent, protonation, and N-alkylation on the nitrogen-15 chemical shifts of pyridine and related compounds

R. Duthaler, J. Roberts, 1978 .

The Relative Stabilities of Substituted cis- and trans-1,2,3,4,4a,9,10,10a-Octahydrophenanthrenes, Including Configurational Corrections in the Elad-Ginsburg Morphine Synthesis

D. Ginsburg, R. Duthaler, 1986 .

The effect of soluble complement receptor type 1 on acute humoral xenograft rejection in hDAF‐transgenic pig‐to‐primate life‐supporting kidney xenografts

U. Christians, J. Higgins, R. Morris, 2005, Xenotransplantation.

Depletion of natural anti-pig antibodies by the continuous infusion of oligosaccharides in a pig-to-baboon model.

D. Sachs, L. Bühler, D. Cooper, 2002, Transplantation proceedings.

Hyperacute rejection of hDAF‐transgenic pig organ xenografts in cynomolgus monkeys: influence of pre‐existing anti‐pig antibodies and prevention by the αGAL glycoconjugate GAS914

G. Berry, B. Reitz, R. Morris, 2004, Xenotransplantation.

Failure to deplete anti‐Galα1‐3Gal antibodies after pig‐to‐baboon organ xenotransplantation by immunoaffinity columns containing multiple Galα1‐3Gal oligosaccharides

R. Mañez, A. Katopodis, N. Domenech, 2004, Xenotransplantation.

Reduction of anti-Galalpha1,3Gal antibodies by infusion of types 2 and 6 gal trisaccharides conjugated to poly-L-lysine.

K. Kuwaki, D. Cooper, H. Schuurman, 2004, Xenotransplantation.

PHOTOCHEMICAL REACTIONS. PART 86. ON THE PHOTOLYSIS OF BICYCLO(3.3.1)NONAN-2-ONE

R. Duthaler, C. Ganter, Regula Susanna Stingelin-Schmid, 1976 .

Substituted 9-Oxabicyclo[4.2.1]- and 9-Oxabicyclo[3.3.1]nonanes (Part II)†

R. Duthaler, C. Ganter, W. Zwahlen, 1971 .

Non-covalent polyvalent ligands by self-assembly of small glycodendrimers: a novel concept for the inhibition of polyvalent carbohydrate-protein interactions in vitro and in vivo.

N. Voelcker, C. Masson, M. Streiff, 2005, Chemistry.

Experiments on the total synthesis of Lysolipin I. Part III. Preparation and transformations of substituted 1,2,3,4‐Tetrahydrodibenzofuran‐1‐ones

R. Duthaler, V. Scherrer, 1984 .

EXPERIMENTS ON THE TOTAL SYNTHESIS OF LYSOLIPIN I. PART III. PREPARATION AND TRANSFORMATIONS OF SUBSTITUTED 1,2,3,4-TETRAHYDRODIBENZOFURAN-1-ONES

R. Duthaler, V. Scherrer, 1985 .

EXPERIMENTS ON THE TOTAL SYNTHESIS OF LYSOLIPIN I. PART I. ON CONFIGURATION AND CONFORMATION OF 5‐SUBSTITUTED 1,2,3,4,4A,9,10,10A‐OCTAHYDROPHENANTHRENE‐4,9‐DIONES

W. Petter, R. Duthaler, P. Mathies, 1984 .

Experiments on the Total Synthesis of Lysolipin I. Part I. On Configuration and Conformation of 5‐Substituted 1,2,3,4,4a,9,10,10a‐Ocathydrophenanthrene‐4,9‐diones

W. Petter, R. Duthaler, P. Mathies, 1984 .

Stereoselective Synthesis of (2S,6S)‐2,6‐Diaminoheptanedioic Acid and of Unsymmetrical Derivatives of meso‐2,6‐Diaminoheptanedioic Acid.

G. Bold, T. Allmendinger, P. Herold, 1992 .

Asymmetric induction bny enantiotopically differentiating retro‐claisen reaction of P{rochiral bicyclic β‐diketones

P. Maienfisch, R. Duthaler, 1984 .

Discovery and Characterization of the Topical Soft JAK Inhibitor CEE321 for Atopic Dermatitis.

G. Thoma, H. Zerwes, P. Rudewicz, 2023, Journal of medicinal chemistry.