J. E. Sharer

Epoxide hydrolase-dependent metabolism of butadiene monoxide to 3-butene-1,2-diol in mouse, rat, and human liver.

A. Elfarra, R. J. Krause, J. E. Sharer, 1997, Drug metabolism and disposition: the biological fate of chemicals.

Comparisons of phase I and phase II in vitro hepatic enzyme activities of human, dog, rhesus monkey, and cynomolgus monkey.

S. Binkley, S. Wrighton, L. Shipley, 1995, Drug metabolism and disposition: the biological fate of chemicals.

Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine.

S. Wrighton, J. E. Sharer, 1996, Drug metabolism and disposition: the biological fate of chemicals.

Formation, stability, and rearrangements of the glutathione conjugates of butadiene monoxide: evidence for the formation of stable sulfurane intermediates.

A. Elfarra, R. J. Duescher, J. E. Sharer, 1991, Chemical research in toxicology.

Species and tissue differences in the microsomal oxidation of 1,3-butadiene and the glutathione conjugation of butadiene monoxide in mice and rats. Possible role in 1,3-butadiene-induced toxicity.

A. Elfarra, R. J. Duescher, J. E. Sharer, 1992, Drug metabolism and disposition: the biological fate of chemicals.

S-(2-hydroxy-3-buten-1-yl)glutathione and S-(1-hydroxy-3-buten-2-yl)glutathione are in vivo metabolites of butadiene monoxide: detection and quantitation in bile.

A. Elfarra, J. E. Sharer, 1992, Chemical research in toxicology.

Synthesis and characterization of N-acetyl-L-cysteine S-conjugates of butadiene monoxide and their detection and quantitation in urine of rats and mice given butadiene monoxide.

A. Elfarra, R. J. Duescher, J. E. Sharer, 1995, Chemical research in toxicology.