M. Harada

发表

Carrier and dose effects on the pharmacokinetics of T-0128, a camptothecin analogue-carboxymethyl dextran conjugate, in non-tumor- and tumor-bearing rats.

S. Okuno, J. Murata, M. Harada, 2001, Journal of controlled release : official journal of the Controlled Release Society.

Determinants for the drug release from T-0128, camptothecin analogue-carboxymethyl dextran conjugate.

S. Okuno, Takehiko Suzuki, T. Yano, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Complete regression of xenografted human carcinomas by camptothecin analogue-carboxymethyl dextran conjugate (T-0128).

N. Tsuda, S. Kiuchi, S. Okuno, 2000, Cancer research.

Improved anti‐tumor activity of stabilized anthracycline polymeric micelle formulation, NC‐6300

H. Saito, N. Shibata, Tatsuyuki Hayashi, 2011, Cancer science.

Effect of combined treatment with the epirubicin‐incorporating micelles (NC‐6300) and 1,2‐diaminocyclohexane platinum (II)‐incorporating micelles (NC‐4016) on a human gastric cancer model

I. Hyodo, Yoshiyuki Yamamoto, Y. Matsumura, 2014, International journal of cancer.

OVA-bound nanoparticles induce OVA-specific IgG1, IgG2a, and IgG2b responses with low IgE synthesis.

J. Mizuguchi, S. Yagyu, Takahiro Seki, 2014, Vaccine.

NC-6301, a polymeric micelle rationally optimized for effective release of docetaxel, is potent but is less toxic than native docetaxel in vivo

K. Miyazono, M. Kano, M. Yashiro, 2012, International journal of nanomedicine.

NC‐6300, an epirubicin‐incorporating micelle, extends the antitumor effect and reduces the cardiotoxicity of epirubicin

N. Ohkohchi, I. Hyodo, Yoshiyuki Yamamoto, 2013, Cancer science.

Reinforcement of antitumor effect of micelles containing anticancer drugs by binding of an anti-tissue factor antibody without direct cytocidal effects.

Sei Yoshida, Y. Matsumura, M. Yasunaga, 2020, Journal of controlled release : official journal of the Controlled Release Society.

A Revolution in Nanomedicines

M. Harada, I. Bobe, I. Nakatomi, 2013 .

Prolonged circulation and in vivo efficacy of recombinant human granulocyte colony-stimulating factor encapsulated in polymeric micelles.

Tatsuyuki Hayashi, M. Harada, Y. Kato, 2011, Journal of controlled release : official journal of the Controlled Release Society.

NC-6004 Phase I study in combination with gemcitabine for advanced solid tumors and population PK/PD analysis

A. Ohtsu, T. Hamaguchi, Y. Shimada, 2017, Cancer Chemotherapy and Pharmacology.

Utility of epirubicin‐incorporating micelles tagged with anti‐tissue factor antibody clone with no anticoagulant effect

I. Hyodo, Yoshiyuki Yamamoto, Y. Matsumura, 2016, Cancer science.

Macrophage-mediated activation of camptothecin analogue T-2513-carboxymethyl dextran conjugate (T-0128): possible cellular mechanism for antitumor activity.

S. Okuno, J. Imai, M. Harada, 2000, Journal of controlled release : official journal of the Controlled Release Society.

Combination therapy with dendritic cell vaccine and IL-2 encapsulating polymeric micelles enhances intra-tumoral accumulation of antigen-specific CTLs.

K. Miki, R. Maekawa, Tatsuyuki Hayashi, 2014, International immunopharmacology.

Enhanced antitumor effect of anti-tissue factor antibody-conjugated epirubicin-incorporating micelles in xenograft models

I. Hyodo, A. Ohtsu, Yoshiyuki Yamamoto, 2015, Cancer science.

Vaccination with OVA-bound nanoparticles encapsulating IL-7 inhibits the growth of OVA-expressing E.G7 tumor cells in vivo.

T. Yoshimoto, J. Mizuguchi, N. Yanase, 2015, Oncology reports.

A prospective, randomized controlled study on the treatment of stage C and stage D prostatic cancer with estracyt in combination with other chemotherapeutic agents.

H. Akaza, Y. Sawamura, M. Otani, 1988, Japanese journal of clinical oncology.

Anti-VEGFR2 antibody-modified micelle for triggered drug delivery and effective therapy of choroidal neovascularization.

H. Hara, M. Shimazawa, Kenichiro Naito, 2019, Current neurovascular research.