J. Weinstock

发表

Dopaminergic activity of substituted 6-chloro-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines.

J. W. Wilson, H. Sarau, A. Tobia, 1982, Journal of medicinal chemistry.

Synthesis and evaluation of non-catechol D-1 and D-2 dopamine receptor agonists: benzimidazol-2-one, benzoxazol-2-one, and the highly potent benzothiazol-2-one 7-ethylamines.

J. Hieble, L. Kinter, D. Gaitanopoulos, 1987, Journal of medicinal chemistry.

Notes- A Modified Curtious Reaction

J. Weinstock, 1961 .

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3 + T-regulatory Cell Function and Promotes Antitumor Immunity

D. Sterner, W. Gu, T. Butt, 2016, EBioMedicine.

Effects of catechol ring fluorination on cardiovascular and renal activities of fenoldopam enantiomers.

R. Ruffolo, L. Kinter, W. Mann, 1994, Chirality.

Characterization of the hemodynamic activities of fenoldopam and its enantiomers in the dog.

R. Ruffolo, L. Kinter, W. Mann, 1990, Chirality.

Renal vasodilators and hypertension

D. M. Ackerman, B. Berkowitz, V. Wiebelhaus, 1982 .

Identification of a small-molecule, nonpeptide macrophage scavenger receptor antagonist.

N. Elshourbagy, P. Lysko, M. Brawner, 1999, The Journal of pharmacology and experimental therapeutics.

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

P. Nguyen, W. Hancock, M. Mattern, 2017, PloS one.

Pharmacological characterization of the nonpeptide angiotensin II receptor antagonist, SK&F 108566.

N. Aiyar, R. Ruffolo, E. Ohlstein, 1992, The Journal of pharmacology and experimental therapeutics.

1-(carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists.

R. Keenan, J. Gleason, J. Hempel, 1991, Journal of medicinal chemistry.

Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes.

R. Edwards, W. Trizna, E. Stack, 1996, The Journal of pharmacology and experimental therapeutics.

Regulation of agonist and antagonist binding to striatal D-1 dopamine receptors: studies using the selective D-1 antagonist [3H]SK&F R-83566.

S. Crooke, J. R. Heys, K. Flaim, 1986, Life sciences.

A novel series of ETA selective antagonists

J. D. Elliott, E. Ohlstein, P. Nambi, 2002 .

Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.

T. Schwartz, S. Hjorth, H. Schambye, 1995, Molecular pharmacology.

Characterization of renal angiotensin II receptors using subtype selective antagonists.

N. Aiyar, R. Keenan, R. Edwards, 1992, The Journal of pharmacology and experimental therapeutics.

Binding of a novel dopaminergic agonist radioligand [3H]-fenoldopam (SKF 82526) to D-1 receptors in rat striatum.

H. Sarau, S. Crooke, K. Flaim, 1985, Life sciences.

A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance.

Parantu K. Shah, N. Munshi, P. Richardson, 2012, Cancer cell.

Synthesis and dopaminergic activity of some halogenated mono- and dihydroxylated 2-aminotetralins.

H. Sarau, J. Hieble, C. Kaiser, 1986, Journal of medicinal chemistry.

Potent nonpeptide angiotensin II receptor antagonists. 2. 1-(Carboxybenzyl)imidazole-5-acrylic acids.

C. E. Peishoff, R. Keenan, D. Gaitanopoulos, 1993, Journal of medicinal chemistry.

SYNTHESIS OF A S-4-CARBOXYPHENYLALANINE DERIVATIVE FOR USE IN PEPTIDE SYNTHESIS

N. Aiyar, J. Samanen, J. Weinstock, 1994 .

Reissert Compounds. Further Alkylation Studies and a Novel Rearrangement1

V. Boekelheide, J. Weinstock, 1952 .

Preparation of Some Cyclopropanes and Stable Sulfoxonium Ylides from Dimethylsulfoxonium Methylide

B. Trost, J. Beeson, C. Kaiser, 1965 .

Preparation of some thiovulpinic acids

B. Sutton, J. Weinstock, Judith E. Blank, 1974 .

Pteridines. X. Some pyrimidopyrimidine isomers of triamterene.

A. J. Villani, J. Weinstock, I. J. Pachter, 1968, Journal of medicinal chemistry.

Synthesis and renal vasodilator activity of some dopamine agonist 1-aryl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diols: halogen and methyl analogues of fenoldopam.

H. Sarau, M. McCarthy, K. Flaim, 1986, Journal of medicinal chemistry.

Regiospecific synthesis of substituted vulpinic acids

H. Oh, B. Sutton, J. Weinstock, 1979 .

Identification of novel inhibitors of the transforming growth factor beta1 (TGF-beta1) type 1 receptor (ALK5).

Ruth Lehr, B. Olson, N. Laping, 2002, Journal of medicinal chemistry.

Amines from Mixed Carboxylic‐Carbonic Anhydrides: 1‐Phenylcyclopentylamine

C. Kaiser, J. Weinstock, 2003 .

cis‐2‐Phenylcyclopropanecarboxylic Acid

C. Kaiser, J. Weinstock, M. Olmstead, 2003 .

A New Synthesis of 3-Fluoroveratrole and 2-Fluoro-3, 4-Dimethoxybenzaldehyde

D. Gaitanopoulos, J. Weinstock, D. Ladd, 1985 .

Improved synthesis of fluoroveratroles and fluorophenethylamines via organolithium reagents

J. Weinstock, D. Ladd, 2002 .

Anomalous Hofmann Elimination Reactions

J. Weinstock, 1956 .

Hofmann Degradation Studies on β-Erythroidine. The Structure of Des-N-methyldihydro-β-erythroidinol1,2

V. Boekelheide, J. Weinstock, 1953 .

Pteridines. XI. Pteridines related to the diuretic, 2,4-diamino-6,7-dimethylpteridine

A. J. Villani, J. Weinstock, June G. Williams, 1968 .

Alkenes via Hofmann Elimination: Use of Ion-Exchange Resin for Preparation of Quaternary Ammonium Hydroxides: Diphenylmethyl Vinyl Ether

C. Kaiser, J. Weinstock, 2003 .

Oral gold. Synthesis and antiarthritic properties of some large-ring gold chelates.

D. T. Walz, B. Sutton, J. Weinstock, 1974, Journal of medicinal chemistry.

and -N-[(1-benzyl-1H-imidazol-5-yl)-alkyl]-amino acids as angiotensin II AT-1 antagonists

C. E. Peishoff, N. Aiyar, E. Ohlstein, 1995 .

Elimination Reactions in Cyclic Systems. VI. Reaction of Iodide Ion with Cyclic trans-Dibromides

F. Bordwell, J. Weinstock, S. N. Lewis, 1956 .

2‐Azabicyclo[2.2.1]heptane‐3‐carboxylic acid ‐ A bicyclic proline

D. Gaitanopoulos, J. Weinstock, 1985 .

The natriuretic and diuretic characteristics of triamterene in the dog.

A. Maass, A. Bender, V. Wiebelhaus, 1967, Archives internationales de pharmacodynamie et de therapie.

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

B. Ueberheide, A. Shilatifard, N. Kelleher, 2018, Clinical Cancer Research.

Mechanisms of .beta.-elimination reactions in which the proton is activated by an electron-withdrawing group

F. Bordwell, J. Weinstock, T. F. Sullivan, 1971 .

Synthesis and dopaminergic binding of 2-aryldopamine analogues: phenethylamines, 3-benzazepines, and 9-(aminomethyl)fluorenes.

K. Flaim, J. Weinstock, J. Sawyer, 1986, Journal of medicinal chemistry.

Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47.

P. Cao, M. Mattern, Jian Wu, 2012, ACS medicinal chemistry letters.

Evidence for a Distinct D1Like Dopamine Receptor that Couples to Activation of Phosphoinositide Metabolism in Brain

H. Sarau, E. Friedman, J. Weinstock, 1994, Journal of neurochemistry.

USP7-Specific Inhibitors Target and Modify the Enzyme's Active Site via Distinct Chemical Mechanisms.

D. Sterner, K. G. S. Kumar, P. Nguyen, 2017, Cell chemical biology.

Chemical Approaches to Intervening in Ubiquitin Specific Protease 7 (USP7) Function for Oncology and Immune Oncology Therapies.

P. Arsenault, M. Mattern, Jian Wu, 2017, Journal of medicinal chemistry.

A Convenient Method for the Large Scale Preparation of (E)-4-Oxo-2-Butenoic Acid Ethyl Ester

J. Weinstock, R. G. Franz, 1988 .

Pteridines. XII. Structure--activity relationships of some pteridine diuretics.

A. Maass, V. Wiebelhaus, J. Weinstock, 1968, Journal of medicinal chemistry.

The Mechanism of γ-Bromoester Pyrolysis

J. Weinstock, 1956 .

Biotransformation of 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylic acid diethyl ester.

S. E. Parker, J. Weinstock, 1973, Journal of medicinal chemistry.

The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism.

R. Ruffolo, D. Brooks, E. Ohlstein, 1992, The Journal of pharmacology and experimental therapeutics.

The Structure of β-Erythroidine and its Derivatives1,2

M. F. Grundon, V. Boekelheide, J. Weinstock, 1953 .

Metabolism of the antihypertensive agent 1,4-dihydro-2,6-dimethyl-4-(2-trifluoromethylphenyl)-3,5-pyridinedicarboxylic acid diethyl ester.

T. Flanagan, J. Weinstock, H. Green, 1973, Journal of pharmaceutical sciences.

Separation of potent central and renal dopamine agonist activity in substituted 6-chloro-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepines.

H. Sarau, A. Tobia, P. Setler, 1980, Journal of medicinal chemistry.

Potential usefulness of renal vasodilators in hypertension and renal disease: SK&F 82526.

J. Mccafferty, B. Berkowitz, J. Weinstock, 1983, Federation proceedings.

SEPARATION OF POTENT CENTRAL AND RENAL DOPAMINE AGONIST ACTIVITY IN SUBSTITUTED 6-CHLORO-2,3,4,5-TETRAHYDRO-7,8-DIHYDROXY-1-PHENYL-1H-3-BENZAZEPINES

H. Sarau, A. Tobia, P. Setler, 1981 .

Dopaminergic Benzazepines with Divergent Cardiovascular Profiles

R. Hahn, H. Sarau, J. Hieble, 1983 .

Identification of fenoldopam prodrugs with prolonged renal vasodilator activity.

K. Erhard, D. Brooks, M. Cyronak, 1990, Journal of Pharmacology and Experimental Therapeutics.

Synthetic studies on prostaglandins.

M. Harman, K. G. Holden, J. Weinstock, 1968, Tetrahedron letters.

Pharmacology of a potent long-acting imidazole-5-acrylic acid angiotensin AT1 receptor antagonist.

N. Aiyar, D. Brooks, E. Ohlstein, 1995, European journal of pharmacology.

Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs

R. Ruffolo, D. Brooks, T. Fredrickson, 1992, Naunyn-Schmiedeberg's Archives of Pharmacology.

A potent long-acting imidazole-5-acrylic acid angiotensin II AT-1 receptor antagonist

N. Aiyar, D. Brooks, E. Ohlstein, 1994 .

A Potent Long‐Acting Imidazole‐5‐acrylic Acid Angiotensin II AT1 Receptor Antagonist

N. Aiyar, D. Brooks, E. Ohlstein, 1994 .

Imidazole-5-acrylic acids: potent nonpeptide angiotensin II receptor antagonists designed using a novel peptide pharmacophore model.

R. Keenan, J. Hempel, D. Gaitanopoulos, 1992, Journal of medicinal chemistry.

Characterization of [3H]SK&F 108566 as a radioligand for angiotensin type-1 receptor.

N. Aiyar, D. Bergsma, A. Shu, 1993, Journal of receptor research.

Elimination Reactions in Cyclic Systems. V. General Base Catalysis of cis and trans Eliminations in the Cyclohexane and Cyclopentane Series1

R. Pearson, F. Bordwell, J. Weinstock, 1956 .

Pteridines. VI. Preparation of some 6-aryl-7-aminopteridines.

B. Trost, B. Sutton, J. Kirkpatrick, 1968, Journal of medicinal chemistry.

Pteridines. 8. Some 2,4,7-triamino-6-heteroarylpteridines.

K. Snader, J. Weinstock, C. B. Karash, 1968, Journal of medicinal chemistry.

Synthesis, conformation, and dopaminergic activity of 5,6-ethano-bridged derivatives of selective dopaminergic 3-benzazepines.

C. Kaiser, D. Eggleston, H. Oh, 1987, Journal of medicinal chemistry.

cis Elimination Mechanisms: The Base-catalyzed Deuterium Exchange of Cycloalkyl p-Tolyl Sulfones

R. Pearson, J. Weinstock, J. L. Bernardi, 1958 .