Zhenzhou Zhang

发表

Sirtuin 7 serves as a promising therapeutic target for cardiorenal diseases.

Ye-ping Zhang, J. Zhong, Xueting Li, 2022, European journal of pharmacology.

The sirtuin 6 prevents angiotensin II-mediated myocardial fibrosis and injury by targeting AMPK-ACE2 signaling

J. Zhong, Yingle Xu, Q. Shang, 2017, Oncotarget.

Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling

G. Oudit, P. Gao, Ding-liang Zhu, 2015, Journal of Translational Medicine.

ACE2/Ang-(1–7) signaling and vascular remodeling

G. Oudit, P. Gao, J. Zhong, 2014, Science China Life Sciences.

Loss of angiotensin-converting enzyme 2 exacerbates myocardial injury via activation of the CTGF-fractalkine signaling pathway.

W. Shen, G. Oudit, P. Gao, 2013, Circulation journal : official journal of the Japanese Circulation Society.

Elabela alleviates ferroptosis, myocardial remodeling, fibrosis and heart dysfunction in hypertensive mice by modulating the IL-6/STAT3/GPX4 signaling.

Jiuchang Zhong, Xiaoyan Liu, Jiawei Song, 2022, Free radical biology & medicine.

Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

J. Penninger, G. Oudit, P. Gao, 2013, Journal of Translational Medicine.

Sirtuin 7 mitigates renal ferroptosis, fibrosis and injury in hypertensive mice by facilitating the KLF15/Nrf2 signaling.

J. Zhong, Jiawei Song, Xueting Li, 2022, Free radical biology & medicine.

Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling

Xiao-Yan Liu, Yifan Fan, R. Miao, 2021, Journal of Molecular Histology.

Ascending aortic adventitial remodeling and fibrosis are ameliorated with Apelin-13 in rats after TAC via suppression of the miRNA-122 and LGR4-β-catenin signaling

G. Oudit, Ding-liang Zhu, J. Zhong, 2016, Peptides.

Angiotensin-converting enzyme 2 attenuates oxidative stress and VSMC proliferation via the JAK2/STAT3/SOCS3 and profilin-1/MAPK signaling pathways

J. Penninger, Jing Ye, Dingliang Zhu, 2013, Regulatory Peptides.

Association of plasma bone morphogenetic protein‐4 levels with arterial stiffness in hypertensive patients

L. Liang, Jiuchang Zhong, Ying Dong, 2022, Journal of clinical laboratory analysis.

Targeting the elabela/apelin-apelin receptor axis as a novel therapeutic approach for hypertension

J. Zhong, Jiawei Song, Zhenzhou Zhang, 2021, Chinese medical journal.

Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury though the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression.

Q. Zhang, Tao Wang, Jiuchang Zhong, 2021, European journal of pharmacology.

Elabela blunts doxorubicin-induced oxidative stress and ferroptosis in rat aortic adventitial fibroblasts by activating the KLF15/GPX4 signaling

J. Zhong, Jiawei Song, Xueting Li, 2022, Cell Stress and Chaperones.

Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases.

J. Vederas, G. Oudit, J. Zhong, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Apelin Is a Negative Regulator of Angiotensin II–Mediated Adverse Myocardial Remodeling and Dysfunction

J. Penninger, G. Oudit, J. Zhong, 2017, Hypertension.

Plasma Levels of Bone Morphogenic Protein-4 Are Downregulated in Elderly Hypertensive Patients with Heart Failure with Preserved Ejection Fraction.

Jiuchang Zhong, Qian Liu, Ying Dong, 2023, Clinical biochemistry.

ACE2/Ang-(1–7) signaling and vascular remodeling

G. Oudit, P. Gao, J. Zhong, 2014, Science China Life Sciences.

Abnormal apelin-ACE2 and SGLT2 signaling contribute to adverse cardiorenal injury in patients with COVID-19

Xiao-Yan Liu, J. Zhong, R. Miao, 2021, International Journal of Cardiology.

Angiotensin-converting enzyme 2 ameliorates renal fibrosis by blocking the activation of mTOR/ERK signaling in apolipoprotein E-deficient mice

G. Oudit, Ding-liang Zhu, J. Zhong, 2016, Peptides.

MicroRNA-122-5p Aggravates Angiotensin II-Mediated Myocardial Fibrosis and Dysfunction in Hypertensive Rats by Regulating the Elabela/Apelin-APJ and ACE2-GDF15-Porimin Signaling

Jiuchang Zhong, Yingle Xu, Jiawei Song, 2022, Journal of Cardiovascular Translational Research.

Deletion of angiotensin-converting enzyme 2 exacerbates renal inflammation and injury in apolipoprotein E-deficient mice through modulation of the nephrin and TNF-alpha-TNFRSF1A signaling

G. Oudit, P. Gao, Ding-liang Zhu, 2015, Journal of Translational Medicine.

Cardiac protective effects of irbesartan via the PPAR-gamma signaling pathway in angiotensin-converting enzyme 2-deficient mice

J. Penninger, G. Oudit, P. Gao, 2013, Journal of Translational Medicine.

MicroRNA-122-5p promotes renal fibrosis and injury in spontaneously hypertensive rats by targeting FOXO3.

Xiao-Yan Liu, J. Zhong, Jiawei Song, 2022, Experimental cell research.

Loss of angiotensin-converting enzyme 2 exacerbates myocardial injury via activation of the CTGF-fractalkine signaling pathway.

W. Shen, G. Oudit, P. Gao, 2013, Circulation journal : official journal of the Japanese Circulation Society.

Ferrostatin-1 Blunts Right Ventricular Hypertrophy and Dysfunction in Pulmonary Arterial Hypertension by Suppressing the HMOX1/GSH Signaling.

Jiuchang Zhong, Siyuan Wang, Jiawei Song, 2023, Journal of cardiovascular translational research.

Expression Profiles of Circular RNA in Aortic Vascular Tissues of Spontaneously Hypertensive Rats

Jiuchang Zhong, Xiaoyan Liu, Ying Dong, 2021, Frontiers in Cardiovascular Medicine.