S. Sperry

发表

Strategies for the modulation of phase II metabolism in a series of PKCε inhibitors.

R. Heim, J. Abt, A. Termin, 2014, Bioorganic & medicinal chemistry letters.

Abstract 2698: eFT226, a potent and selective inhibitor of eIF4A, is efficacious in preclinical models of lymphoma

P. A. Thompson, K. Webster, N. Young, 2019, Experimental and Molecular Therapeutics.

Structure-based Design of Pyridone-Aminal eFT508 Targeting Dysregulated Translation by Selective Mitogen-activated Protein Kinase Interacting Kinases 1 and 2 (MNK1/2) Inhibition.

P. A. Thompson, C. Stumpf, Qing Han, 2018, Journal of medicinal chemistry.

Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase.

P. A. Thompson, K. Webster, N. Young, 2020, Journal of medicinal chemistry.

eFT508, a Potent and Selective Mitogen-Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 Inhibitor, Is Efficacious in Preclinical Models of Diffuse Large B-Cell Lymphoma (DLBCL)

P. A. Thompson, K. Webster, Katti A. Jessen, 2015 .

Abstract 596: eFT508, a potent and highly selective inhibitor of MNK1/2 regulates immune checkpoint and cytokine expression promoting anti-tumor immunity

P. A. Thompson, C. Stumpf, K. Webster, 2017 .

Abstract PR11: eFT508: An oral, potent and highly selective inhibitor of MNK1 and MNK2, promotes anti-tumor immunity as a monotherapy and in combination with immune checkpoint blockade

P. A. Thompson, C. Stumpf, K. Webster, 2017 .

In vitro and in vivo antitumor activities of SGX523, a novel MET inhibitor

S. Burley, Marshall C. Peterman, K. Froning, 2007 .

Dihydrotubastrines: phenethylguanidine analogues from the Indo-Pacific marine sponge Petrosia cf. contignata.

P. Crews, S. Sperry, 1998, Journal of natural products.

Isolation and cytotoxic evaluation of marine sponge-derived norterpene peroxides.

F. Valeriote, P. Crews, T. Corbett, 1998, Journal of natural products.

Vertinoid Polyketides from the Saltwater Culture of the Fungus Trichoderma longibrachiatum Separated from a Haliclona Marine Sponge.

Phillip Crews, P. Crews, G. Samuels, 1999 .

A novel alkaloid from the Indo-Pacific sponge Clathria basilana

P. Crews, S. Sperry, 1996 .

A Novel Alkaloid from the Indo-Pacific Sponge Clathria basilana.

P. Crews, S. Sperry, 1996 .

Vertinoid Polyketides from the Saltwater Culture of the Fungus Trichoderma longibrachiatum Separated from a Haliclona Marine Sponge

P. Crews, G. Samuels, S. Sperry, 1998 .

Identification of novel HSP90α/β isoform selective inhibitors using structure-based drug design. demonstration of potential utility in treating CNS disorders such as Huntington's disease.

Beth A. Fleck, L. Goulet, J. Ernst, 2014, Journal of medicinal chemistry.

Targeting Oncogene mRNA Translation in B-Cell Malignancies with eFT226, a Potent and Selective Inhibitor of eIF4A

P. A. Thompson, K. Webster, N. Young, 2020, Molecular Cancer Therapeutics.

Preclinical Evaluation of eFT226, a Novel, Potent and Selective eIF4A Inhibitor with Anti-Tumor Activity in B-Cell Malignancies

P. A. Thompson, K. Webster, N. Young, 2017 .

Haliclostanone sulfate and halistanol sulfate from an Indo-Pacific Haliclona sponge.

P. Crews, S. Sperry, 1997, Journal of natural products.