C. Grol

发表

Synthesis and Pharmacology of the enantiomers of the potential atypical antipsychotic agents 5-OMe-BPAT and 5-OMe-(2,6-di-OMe)-BPAT.

H. Wikström, D. Jackson, E. Homan, 1999, Bioorganic & medicinal chemistry.

A new dopaminergic prodrug

M. Feenstra, H. Rollema, D. Dijkstra, 1978, Nature.

Semipreparative enantiomeric separation of a series of putative melatonin receptor agents using tri-acetylcellulose as chiral stationary phase.

D. T. Witte, J. Jansen, R. Isaksson, 1994, Chirality.

An improved synthesis of the enantiomers of BM-5 and their effects on the central in vivo release of acetylcholine.

U. Hacksell, P. de Boer, C. Grol, 1992, Chirality.

5‐Oxygenated N‐Alkyl‐and N,N‐Dialkyl‐2‐amino‐1‐methyltetralins. Effects of Structure and Stereochemistry on Dopamine‐D2‐receptor Affinity

U. Hacksell, G. Nordvall, A. Johansson, 1991, The Journal of pharmacy and pharmacology.

Correlation between neuroleptic‐induced suppression of stereotyped behaviour and HVA concentrations in rat brain

B. Westerink, H. Rollema, C. Grol, 1976, The Journal of pharmacy and pharmacology.

Kinetic and pharmacological profiles of the in vitro binding of the potent dopamine agonist [3H]N,N-dipropyl-5,6-dihydroxy-2-aminotetralin to rat striatal membranes.

D. Dijkstra, A. Horn, C. Grol, 1985, European journal of pharmacology.

DITHIENOTHIAZINES AND THIENOBENZOTHIAZINES

C. Grol, C. J. Grol, 1974 .

Synthesis of a dithieno[2,3-b:3′,2′-e][1,4]thiazine and of di-3-thienylamine

C. Grol, 1975 .

Synthesis and pharmacological evaluation of 5,6,7,8‐tetrahydro‐6‐[propyl[2‐(2‐thienyl)ethyl]amino]‐1,2‐naphthalenediol: A novel non‐selective dopamine‐receptor agonist

D. Dijkstra, A. Horn, J. Vries, 2010 .

C5-substituted derivatives of 5-OMe-BPAT: synthesis and interactions with dopamine D2 and serotonin 5-HT1A receptors.

H. Wikström, E. Homan, J. Nilsson, 1999, Bioorganic & medicinal chemistry.

Synthesis of dithieno[2,3-b:3′,2′-e]-8H-thiopyran-8-thione and dithieno[2,3-b:3′,2′-e]-8H-thiopyran-8-one

C. Grol, 1974 .

Novel 5-HT7 receptor inverse agonists. Synthesis and molecular modeling of arylpiperazine- and 1,2,3,4-tetrahydroisoquinoline-based arylsulfonamides.

Anne W. Schmidt, H. Wikström, E. S. Vermeulen, 2004, Journal of medicinal chemistry.

Synthesis and pharmacological evaluation of conformationally restricted phenothiazine analogues.

B. Westerink, A. Martin, D. Dijkstra, 1982, Journal of medicinal chemistry.

A multiway 3D QSAR analysis of a series of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxybenzamides

Age K. Smilde, Jonas Nilsson, Evert J. Homan, 1998, J. Comput. Aided Mol. Des..

The high affinity melationin binding site probed with conformationally restricted ligand--I. Pharmacophore and minireceptor models.

J. Jansen, M. Dubocovich, J M Jansen, 1996, Bioorganic & medicinal chemistry.

2-aminotetralin-derived substituted benzamides with mixed dopamine D2, D3, and serotonin 5-HT1A receptor binding properties: a novel class of potential atypical antipsychotic agents.

H. Wikström, L. Elfström, E. Homan, 1998, Bioorganic & medicinal chemistry.

Further in vitro and in vivo studies with the putative presynaptic dopamine agonist N,N-dipropyl-7-hydroxy-2-aminotetralin

J. Wiechers, D. Dijkstra, A. Horn, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

S(−)DP-5,6-ADTN as an in vivo dopamine receptor ligand: Relation between displacement by dopamine agonists and their pharmacological effects

R. Mailman, Mark H Lewis, M. Feenstra, 1986, Naunyn-Schmiedeberg's Archives of Pharmacology.

A SIMPLE, UNEXPECTED REGIOSELECTIVE CHLORINATION OF A SERIES OF 5-OH-2(ALKYLAMINO)TETRALINS - POTENTIAL DOPAMINERGIC AGENTS

D. Dijkstra, C. Grol, 1992 .

Effect of dihydroxy-2-aminotetralin derivatives on dopamine metabolism in the rat striatum

B. Westerink, M. Feenstra, H. Rollema, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Facile syntheses of potent dopaminergic argonists and their effect on neurotransmitter release.

A. H. Mulder, D. Dijkstra, A. Horn, 1978, Journal of medicinal chemistry.

Effect of non-catecholic 2-aminotetralin derivatives on dopamine metabolism in the rat striatum

B. Westerink, M. Feenstra, H. Rollema, 1980, Naunyn-Schmiedeberg's Archives of Pharmacology.

FACILE SYNTHESES OF POTENT DOPAMINERGIC AGONISTS AND THEIR EFFECTS ON NEUROTRANSMITTER RELEASE

A. H. Mulder, D. Dijkstra, A. Horn, 1978 .

Molecular modeling of the dopamine D2 and serotonin 5-HT1A receptor binding modes of the enantiomers of 5-OMe-BPAT.

H. Wikström, E. Homan, H V Wikström, 1999, Bioorganic & medicinal chemistry.

The high affinity melatonin binding site probed with conformationally restricted ligands--II. Homology modeling of the receptor.

J. Jansen, C. Grol, C. J. Grol, 1996, Bioorganic & medicinal chemistry.

Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site.

Anne W. Schmidt, H. Wikström, E. S. Vermeulen, 2003, Journal of medicinal chemistry.

THE NEUROCHEMICAL PROFILE OF A PRODRUG OF ADTN

H. Rollema, D. Dijkstra, B. Westerink, 1979 .

Structural analogues of 5-OMe-BPAT: synthesis and interactions with dopamine D2, D3, and serotonin 5-HT1A receptors.

H. Wikström, E. Homan, N. Mohell, 1999, Bioorganic & medicinal chemistry.