M. Gasparian

发表

Biochemical characterization of human enteropeptidase light chain

D. Dolgikh, M. Kirpichnikov, Valeriy G Ostapchenko, 2006, Biochemistry (Moscow).

Expression, purification, and characterization of human enteropeptidase catalytic subunit in Escherichia coli.

A. Schulga, D. Dolgikh, M. Kirpichnikov, 2003, Protein expression and purification.

Combination of TRAIL with Bortezomib Shifted Apoptotic Signaling from DR4 to DR5 Death Receptor by Selective Internalization and Degradation of DR4

D. Dolgikh, M. Kirpichnikov, M. Gasparian, 2014, PloS one.

Na,K-ATPase extracellular surface probed with a monoclonal antibody that enhances ouabain binding.

K. Sweadner, N. Modyanov, E. Arystarkhova, 1992, The Journal of biological chemistry.

An efficient method for expression in Escherichia coli and purification of the extracellular ligand binding domain of the human TGFbeta type II receptor.

D. Dolgikh, M. Kirpichnikov, S. Yakimov, 2010, Journal of biotechnology.

Overexpression and refolding of thioredoxin/TRAIL fusion from inclusion bodies and further purification of TRAIL after cleavage by enteropeptidase

D. Dolgikh, M. Kirpichnikov, B. Chernyak, 2007, Biotechnology Letters.

Overexpression in Escherichia coli and purification of human fibroblast growth factor (FGF-2)

D. Dolgikh, M. Kirpichnikov, N. Drize, 2009, Biochemistry (Moscow).

Mutations enhancing selectivity of antitumor cytokine TRAIL to DR5 receptor increase its cytotoxicity against tumor cells

D. Dolgikh, M. Kirpichnikov, M. Gasparian, 2015, Biochemistry (Moscow).

Identification and characterization of an 18-kilodalton, VAMP-like protein in suspension-cultured carrot cells.

F. Filippini, P. P. de Laureto, B. Baldan, 2000, Plant physiology.

Identification and Characterization of an 18-Kilodalton , VAMP-Like Protein in Suspension-Cultured Carrot Cells 1

P. P. Laureto, F. Filippini, B. Baldan, 2000 .

Death Receptors DR4 and DR5 Undergo Spontaneous and Ligand-Mediated Endocytosis and Recycling Regardless of the Sensitivity of Cancer Cells to TRAIL

D. Dolgikh, M. Kirpichnikov, D. Trushina, 2021, Frontiers in Cell and Developmental Biology.

Chemotherapeutic Agents Sensitize Resistant Cancer Cells to the DR5-Specific Variant DR5-B More Efficiently Than to TRAIL by Modulating the Surface Expression of Death and Decoy Receptors

D. Dolgikh, M. Kirpichnikov, S. Deyev, 2020, Cancers.

Optimized Heterologous Expression and Efficient Purification of a New TRAIL-Based Antitumor Fusion Protein SRH–DR5-B with Dual VEGFR2 and DR5 Receptor Specificity

D. Dolgikh, M. Kirpichnikov, A. Artykov, 2022, International journal of molecular sciences.

Genetically Modified DR5-Specific TRAIL Variant DR5-B Revealed Dual Antitumor and Protumoral Effect in Colon Cancer Xenografts and an Improved Pharmacokinetic Profile

D. Dolgikh, M. Kirpichnikov, M. Vorontsova, 2020, Translational oncology.

A New Efficient Method for Production of Recombinant Antitumor Cytokine TRAIL and Its Receptor-Selective Variant DR5-B

D. Dolgikh, M. Kirpichnikov, A. Artykov, 2019, Biochemistry (Moscow).

Application of an Autoinduction Strategy to Optimize the Heterologous Production of an Antitumor Bispecific Fusion Protein Based on the TRAIL Receptor-Selective Mutant Variant in Escherichia coli

Alina Isakova, D. Dolgikh, A. Artykov, 2022, Molecular Biotechnology.

Effects of Fibroblast Growth Factor-2 and Other Microsupplements on the Productivity of IgG- and IgA-Producing Cell Lines

D. Dolgikh, M. Kirpichnikov, T. Aliev, 2020, Applied Biochemistry and Microbiology.

New Strategy for High-Level Expression and Purification of Biologically Active Monomeric TGF-β1/C77S in Escherichia coli

E. N. Tkach, D. Dolgikh, M. Kirpichnikov, 2015, Molecular Biotechnology.

DR5-Selective TRAIL Variant DR5-B Functionalized with Tumor-Penetrating iRGD Peptide for Enhanced Antitumor Activity against Glioblastoma

D. Dolgikh, M. Kirpichnikov, M. Pavlyukov, 2022, International journal of molecular sciences.

Recent Advances in the Development of Nanodelivery Systems Targeting the TRAIL Death Receptor Pathway

D. Dolgikh, M. Gasparian, A. V. Yagolovich, 2023, Pharmaceutics.

Strategy for improvement of enteropeptidase efficiency in tag removal processes.

D. Dolgikh, M. Kirpichnikov, M. Gasparian, 2011, Protein expression and purification.

Mutations enhancing selectivity of antitumor cytokine TRAIL to DR5 receptor increase its cytotoxicity against tumor cells

D. Dolgikh, M. Kirpichnikov, M. Gasparian, 2015, Biochemistry (Moscow).

Generation of new TRAIL mutants DR5-A and DR5-B with improved selectivity to death receptor 5

D. Dolgikh, M. Kirpichnikov, B. Chernyak, 2009, Apoptosis.

Doxorubicin-Loaded Polyelectrolyte Multilayer Capsules Modified with Antitumor DR5-Specific TRAIL Variant for Targeted Drug Delivery to Tumor Cells

D. Trushina, E. Markvicheva, S. Burov, 2023, Nanomaterials.

Application of an Autoinduction Strategy to Optimize the Heterologous Production of an Antitumor Bispecific Fusion Protein Based on the TRAIL Receptor-Selective Mutant Variant in Escherichia coli

D. Dolgikh, A. Artykov, M. Gasparian, 2022, Molecular Biotechnology.

Amphiphilic Poly(N-vinylpyrrolidone) Nanoparticles Conjugated with DR5-Specific Antitumor Cytokine DR5-B for Targeted Delivery to Cancer Cells

D. Bagrov, V. Oleinikov, D. Dolgikh, 2021, Pharmaceutics.

A New Efficient Method for Production of Recombinant Antitumor Cytokine TRAIL and Its Receptor-Selective Variant DR5-B

D. Dolgikh, M. Kirpichnikov, A. Artykov, 2019, Biochemistry (Moscow).

The effect of cisplatin on cytotoxicity of anticancer cytokine TRAIL and its receptor-selective mutant variant DR5-B1

M. Kirpichnikov, M. Gasparian, M. Bychkov, 2017, Doklady Biochemistry and Biophysics.

Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2

D. Dolgikh, B. Chernyak, L. V. Domnina, 2008, Biochemistry (Moscow).

ONC201-Induced Mitochondrial Dysfunction, Senescence-like Phenotype, and Sensitization of Cultured BT474 Human Breast Cancer Cells to TRAIL

I. Beletsky, V. Galat, E. Holmuhamedov, 2022, International journal of molecular sciences.

Heterogeneous catalysis on the phage surface: Display of active human enteropeptidase.

D. Dolgikh, M. Kirpichnikov, T. Bobik, 2013, Biochimie.

The secretory nature of the lesion of carrot cell variant ts11, rescuable by endochitinase

F. Filippini, S. D. de Vries, A. Vitale, 1997, Planta.

Dissecting structural basis of the unique substrate selectivity of human enteropeptidase catalytic subunit

D. Dolgikh, M. Kirpichnikov, Yurij A. Kosinsky, 2012, Journal of biomolecular structure & dynamics.

The effect of cisplatin on cytotoxicity of anticancer cytokine TRAIL and its receptor-selective mutant variant DR5-B1

D. Dolgikh, M. Kirpichnikov, M. Gasparian, 2017, Doklady Biochemistry and Biophysics.

Infection of stromal and hemopoietic precursor cells with lentivirus vector in vivo and in vitro

V. Surin, N. Drize, N. Sats, 2008, Bulletin of Experimental Biology and Medicine.

Dual targeting of DR5 and VEGFR2 molecular pathways by multivalent fusion protein significantly suppresses tumor growth and angiogenesis.

A. Artykov, M. Gasparian, A. V. Yagolovich, 2023, International journal of biological macromolecules.