Xinle Wu

发表

The veA gene is necessary for the inducible expression by fructosyl amines of the Aspergillus nidulansfaoA gene encoding fructosyl amino acid oxidase (amadoriase, EC 1.5.3)

V. Monnier, Dong-Min Han, K. Jahng, 2002, Archives of Microbiology.

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

P. Emmerson, P. Mitchell, R. Gimeno, 2017, Nature Medicine.

Treating Diabetes and Obesity with an FGF21-Mimetic Antibody Activating the βKlotho/FGFR1c Receptor Complex

T. Arora, Zhulun Wang, L. Sekirov, 2012, Science Translational Medicine.

A Novel Approach to Improve the Function of FGF21

Jing Xu, Richard Smith, Amy N. Duguay, 2013, BioDrugs.

Therapeutic utilities of fibroblast growth factor 19

Yang Li, Xinle Wu, 2011, Expert opinion on therapeutic targets.

Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice

Y. Li, Yang Li, R. Lindberg, 2009, FEBS letters.

A unique FGF23 with the ability to activate FGFR signaling through both αKlotho and βKlotho.

N. Hawkins, Minghan Wang, Yang Li, 2012, Journal of molecular biology.

Dual actions of fibroblast growth factor 19 on lipid metabolism[S]

B. Lemon, Minghan Wang, Yang Li, 2013, Journal of Lipid Research.

Dual actions of figrowth factor 19 on lipid metabolism

B. Lemon, Minghan Wang, Yang Li, 2013 .

FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation

B. Lemon, Zhulun Wang, R. Lindberg, 2009, The Journal of Biological Chemistry.

Characterization of a FGF19 Variant with Altered Receptor Specificity Revealed a Central Role for FGFR1c in the Regulation of Glucose Metabolism

B. Lemon, Minghan Wang, Yang Li, 2012, PloS one.

The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21.

B. Lemon, Zhulun Wang, R. Lindberg, 2011, Journal of molecular biology.

Selective activation of FGFR4 by an FGF19 variant does not improve glucose metabolism in ob/ob mice

B. Lemon, N. Hawkins, R. Lindberg, 2009, Proceedings of the National Academy of Sciences.

C-terminal Tail of FGF19 Determines Its Specificity toward Klotho Co-receptors*

B. Lemon, N. Hawkins, R. Lindberg, 2008, Journal of Biological Chemistry.

Dual actions of fi broblast growth factor 19 on lipid metabolism

Y. Li, B. Lemon, Minghan Wang, 2013 .

Enzymatic deglycation of proteins.

V. Monnier, Xinle Wu, 2003, Archives of biochemistry and biophysics.

Signaling property study of adhesion G‐protein‐coupled receptors

Yang Li, H. Tian, J. Gupte, 2012, FEBS letters.

Trefoil Factor 3 (TFF3) Is Regulated by Food Intake, Improves Glucose Tolerance and Induces Mucinous Metaplasia

Li Yang, Li Yang, W. Yeh, 2015, PloS one.

Mammalian sprouty proteins assemble into large monodisperse particles having the properties of intracellular nanobatteries.

S. McKnight, M. Kikkawa, P. Vogel, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Alteration of substrate selectivity through mutation of two arginine residues in the binding site of amadoriase II from Aspergillus sp.

V. Monnier, Shu G. Chen, J. Petrash, 2002, Biochemistry.

Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.

Carol Dudley, Steven L McKnight, Ramon Diaz-Arrastia, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Signaling Pathways in Liver Cancer

Yang Li, Xinle Wu, 2012 .

The neuronal PAS domain protein 3 transcription factor controls FGF-mediated adult hippocampal neurogenesis in mice.

D. Brat, S. McKnight, J. Richardson, 2005, Proceedings of the National Academy of Sciences of the United States of America.

GDF15 and Growth Control

P. Emmerson, K. Duffin, Sudhakar Chintharlapalli, 2018, Front. Physiol..

Separating mitogenic and metabolic activities of fibroblast growth factor 19 (FGF19)

B. Lemon, Z. Wang, Zhulun Wang, 2010, Proceedings of the National Academy of Sciences.

Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasis

Yang Li, Xinle Wu, 2009, Aging.

Co-receptor Requirements for Fibroblast Growth Factor-19 Signaling*

B. Lemon, N. Hawkins, Yang Li, 2007, Journal of Biological Chemistry.

Soluble CLEC2 Extracellular Domain Improves Glucose and Lipid Homeostasis by Regulating Liver Kupffer Cell Polarization

W. Richards, B. Lemon, Yan Gong, 2015, EBioMedicine.

FGF21 Can Be Mimicked In Vitro and In Vivo by a Novel Anti-FGFR1c/β-Klotho Bispecific Protein

Richard Smith, M. Véniant, A. Bakker, 2013, PloS one.

Understanding the structure-function relationship between FGF19 and its mitogenic and metabolic activities.

Yang Li, Xinle Wu, 2012, Advances in experimental medicine and biology.

The prospects of health and longevity from the inhibition of the Maillard reaction in vivo

V. Monnier, D. Sell, Xinle Wu, 2002 .

A Novel Approach to Improve the Function of FGF21

Richard Smith, Amy N. Duguay, Yang Li, 2013, BioDrugs.

A unique FGF23 with the ability to activate FGFR signaling through both αKlotho and βKlotho.

N. Hawkins, Minghan Wang, Yang Li, 2012, Journal of Molecular Biology.

Therapeutic utilities of fibroblast growth factor 19

Yang Li, Xinle Wu, 2011, Expert opinion on therapeutic targets.

The FGFR D3 domain determines receptor selectivity for fibroblast growth factor 21.

B. Lemon, Zhulun Wang, R. Lindberg, 2011, Journal of molecular biology.

Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice

Yang Li, R. Lindberg, M. Véniant, 2009, FEBS letters.

Advancing therapeutic discovery through phenotypic screening of the extracellular proteome using hydrodynamic intravascular injection

Li Yang, P. Kassner, Yan Gong, 2014, Expert opinion on therapeutic targets.