L. González

M. Dagleish, L. Terry, R. Horton, 2008, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

Occurrence and distribution of infection-specific PrP in tissues of clinical scrapie cases and cull sheep from scrapie-affected farms in Shetland.

M. Jeffrey, L. González, S. Martín, 2002, Journal of comparative pathology.

Running title : Transmission of sheep TSEs by blood transfusion

N. Hunter, A. Chong, W. Goldmann, 2010 .

A prion reduction filter does not completely remove endogenous prion infectivity from sheep blood

M. Turner, N. E. Appleford, J. Manson, 2015, Transfusion.

Minimal involvement of the circumventricular organs in the pathogenesis of spontaneously arising and experimentally induced classical bovine spongiform encephalopathy.

M. Simmons, T. Konold, S. Sisó, 2012, Journal of comparative pathology.

Disease phenotype in sheep after infection with cloned murine scrapie strains

W. Goldmann, F. Chianini, P. Steele, 2012, Prion.

Three serial passages of bovine spongiform encephalopathy in sheep do not significantly affect discriminatory test results.

R. Sayers, S. Bellworthy, M. Jeffrey, 2009, The Journal of general virology.

Comparative titration of experimental ovine BSE infectivity in sheep and mice.

F. Chianini, S. Sisó, H. Reid, 2007, The Journal of general virology.

The neuropathologic phenotype of experimental ovine BSE is maintained after blood transfusion.

N. Hunter, S. Sisó, F. Houston, 2006, Blood.

Onset and distribution of tissue prp accumulation in scrapie-affected suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies.

M. Jeffrey, W. S. Dingwall, L. González, 2001, Journal of comparative pathology.

Monoclonal and polyclonal antibodies for ante- and post-mortem detection of PrPSc in sheep.

J. R. E. Filho, D. Driemeier, M. D. Costa, 2015 .

Influence of polymorphisms in the prion protein gene on the pathogenesis and neuropathological phenotype of sheep scrapie after oral infection.

C. Acín, H. Simmons, J. Pitarch, 2014, Journal of comparative pathology.

Pathogenesis of scrapie in ARQ/ARQ sheep after subcutaneous infection: effect of lymphadenectomy and immune cell subset changes in relation to prion protein accumulation.

F. Chianini, P. Steele, S. Hamilton, 2013, Veterinary immunology and immunopathology.

CD21 B cell populations are altered following subcutaneous scrapie inoculation in sheep.

F. Chianini, S. Hamilton, S. Eaton, 2009, Veterinary immunology and immunopathology.

Disease-associated PrP in the enteric nervous system of scrapie-affected Suffolk sheep.

A. Espenes, C. Press, M. Jeffrey, 2003, The Journal of general virology.

Neuroinvasion in Prion Diseases: The Roles of Ascending Neural Infection and Blood Dissemination

S. Sisó, M. Jeffrey, L. González, 2010, Interdisciplinary perspectives on infectious diseases.

Transportation of prion protein across the intestinal mucosa of scrapie‐susceptible and scrapie‐resistant sheep

A. Espenes, C. Press, M. Jeffrey, 2006, The Journal of pathology.

Immunohistochemical and biochemical characterisation of BSE and CWD in experimentally infected European red deer (cervus elaphus).

W. Goldmann, M. Simmons, J. Spiropoulos, 2010 .

Immunohistochemical and biochemical characteristics of BSE and CWD in experimentally infected European red deer (Cervus elaphus elaphus)

P. Steele, S. Sisó, H. Reid, 2009, BMC veterinary research.

Bluetongue in northern Europe

E. Thiry, C. Saegerman, K. De Clercq, 2006, Veterinary Record.

Diagnosis of preclinical scrapie in samples of rectal mucosa

S. Bellworthy, S. Sisó, H. Reid, 2005, Veterinary Record.

Pathological phenotype of sheep scrapie after blood transfusion.

N. Hunter, S. Sisó, F. Houston, 2010, Journal of comparative pathology.

Influence of breed and genotype on the onset and distribution of infectivity and disease-associated prion protein in sheep following oral infection with the bovine spongiform encephalopathy agent.

S. Bellworthy, J. Spiropoulos, M. Jeffrey, 2015, Journal of comparative pathology.

Prion diseases: BSE in sheep bred for resistance to infection

N. Hunter, D. Parnham, A. Chong, 2003, Nature.

Occurrence and cellular localization of PrPd in kidneys of scrapie‐affected sheep in the absence of inflammation

F. Chianini, P. Steele, S. Sisó, 2008, The Journal of pathology.

PrPCWD in rectal lymphoid tissue of deer (Odocoileus spp.).

M. Dagleish, L. Wolfe, M. Jeffrey, 2007, The Journal of general virology.

Immunocytochemical Detection of Listeria monocytogenes in Tissue with the Peroxidase-antiperoxidase Technique

M. Domingo, L. Domínguez, A. Marco, 1988, Veterinary pathology.

Identical pathogenesis and neuropathological phenotype of scrapie in valine, arginine, glutamine/valine, arginine, glutamine sheep infected experimentally by the oral and conjunctival routes.

C. Acín, J. Pitarch, M. Jeffrey, 2014, Journal of comparative pathology.

Transmission of classical scrapie via goat milk

T. Konold, H. Simmons, S. Hawkins, 2013, Veterinary Record.

Neuroinvasion in sheep transmissible spongiform encephalopathies: the role of the haematogenous route

S. Sisó, M. Jeffrey, L. González, 2009, Neuropathology and applied neurobiology.

The distribution of immune cells in the lungs of classical and atypical ovine pulmonary adenocarcinoma.

M. Norval, J. A. García de Jalón, A. Ortín, 2012, Veterinary immunology and immunopathology.

Pathogenesis of natural goat scrapie: modulation by host PRNP genotype and effect of co-existent conditions

W. Goldmann, S. Sisó, M. Jeffrey, 2010, Veterinary research.

Infectious titres of sheep scrapie and bovine spongiform encephalopathy agents cannot be accurately predicted from quantitative laboratory test results.

Thomas M. Holder, J. Spiropoulos, L. Terry, 2012, The Journal of general virology.

A PCR technique for the detection of Jaagsiekte sheep retrovirus in the blood suitable for the screening of ovine pulmonary adenocarcinoma in field conditions.

J. A. García de Jalón, A. Ortín, D. Salvatori, 2005, Research in veterinary science.

Successful induction of ovine pulmonary adenocarcinoma in lambs of different ages and detection of viraemia during the preclinical period.

R. Dalziel, D. Salvatori, C. Cousens, 2004, The Journal of general virology.

Detection of immune system cells in paraffin wax-embedded ovine tissues.

D. Buxton, I. Anderson, D. Deane, 2001, Journal of comparative pathology.

Sheep pulmonary adenomatosis: characterization of two pathological forms associated with jaagsiekte retrovirus.

E. Minguijón, A. Ortín, J. Sharp, 2000, Journal of comparative pathology.

Lack of a specific immune response against a recombinant capsid protein of Jaagsiekte sheep retrovirus in sheep and goats naturally affected by enzootic nasal tumour or sheep pulmonary adenomatosis.

M. Palmarini, M. García, E. Minguijón, 1998, Veterinary immunology and immunopathology.

Mechanism of PrP‐Amyloid Formation in Mice Without Transmissible Spongiform Encephalopathy

Emily V. Chambers, B. Ghetti, Declan King, 2012, Brain pathology.

Monitoring of clinical signs in goats with transmissible spongiform encephalopathies

S. Cawthraw, W. Goldmann, M. Simmons, 2010, BMC veterinary research.

Diagnostic pathology in microbial diseases of sheep or goats.

J. Benavides, M. Dagleish, V. Pérez, 2015, Veterinary microbiology.

Evaluation of a PCR technique for the detection of Maedi-Visna proviral DNA in blood, milk and tissue samples of naturally infected sheep

R. Juste, M. García, L. González, 2002 .

Transmission and control implications of seroconversion to Maedi-Visna virus in Basque dairy-sheep flocks.

R. Juste, E. Berriatua, V. Álvarez, 2003, Preventive veterinary medicine.

Control of brucellosis and of respiratory Small Ruminant Lentivirus infection in small ruminants in the Basque country, Spain

R. Juste, N. Elguezabal, E. Minguijón, 2013 .

Evidence of scrapie transmission to sheep via goat milk

M. Simmons, T. Konold, H. Simmons, 2016, BMC Veterinary Research.

Jaagsiekte sheep retrovirus can be detected in the peripheral blood during the pre-clinical period of sheep pulmonary adenomatosis.

A. Ortín, J. Sharp, C. Cousens, 2001, The Journal of general virology.

Sensory circumventricular organs in health and disease

S. Sisó, M. Jeffrey, L. González, 2010, Acta Neuropathologica.

Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom

D. Parnham, W. Goldmann, O. Windl, 2011, Veterinary research.

Pulmonary Adenomatosis Naturally and Experimentally Acquired Mononuclear Phagocytes of Sheep with both in T and B Lymphocytes and in Jaagsiekte Retrovirus Is Widely Distributed

M. Palmarini, M. Holland, I. McKendrick, 1999 .

Against All Odds: RNA Extraction From Different Protocols Adapted to Formalin-fixed Paraffin-embedded Tissue

C. Cirqueira, L. Kimura, J. Guerra, 2020, Applied immunohistochemistry & molecular morphology : AIMM.

High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age.

W. Goldmann, O. Windl, J. Hope, 2009, Veterinary research.

Pathology of SSLOW, a transmissible and fatal synthetic prion protein disorder, and comparison with naturally occurring classical transmissible spongiform encephalopathies

N. Makarava, I. Baskakov, R. Rohwer, 2014, Neuropathology and applied neurobiology.

Diagnosis of preclinical scrapie in live sheep by the immunohistochemical examination of rectal biopsies

P. Steele, J. Finlayson, M. Dagleish, 2008, Veterinary Record.

Abnormalities in Brainstem Auditory Evoked Potentials in Sheep with Transmissible Spongiform Encephalopathies and Lack of a Clear Pathological Relationship

S. Cawthraw, M. Simmons, T. Konold, 2016, Front. Vet. Sci..

Dynamics of the natural transmission of bovine spongiform encephalopathy within an intensively managed sheep flock

S. Bellworthy, M. Jeffrey, S. Hawkins, 2015, Veterinary Research.

Susceptibility of European Red Deer (Cervus elaphus elaphus) to Alimentary Challenge with Bovine Spongiform Encephalopathy

J. Castilla, W. Goldmann, F. Chianini, 2015, PloS one.

Immunophenotype of cells within cervine rectoanal mucosa-associated lymphoid tissue and mesenteric lymph nodes.

F. Chianini, P. Steele, S. Hamilton, 2012, Journal of comparative pathology.

Factors influencing temporal variation of scrapie incidence within a closed Suffolk sheep flock.

W. Goldmann, F. Chianini, P. Steele, 2012, The Journal of general virology.

Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa

J. Hughes, S. Bellworthy, S. Sisó, 2006, Veterinary Record.

Immunohistochemical characteristics of disease-associated PrP are not altered by host genotype or route of inoculation following infection of sheep with bovine spongiform encephalopathy.

N. Hunter, A. Chong, F. Houston, 2005, The Journal of general virology.

Effects of agent strain and host genotype on PrP accumulation in the brain of sheep naturally and experimentally affected with scrapie.

N. Hunter, M. Simmons, F. Houston, 2002, Journal of comparative pathology.

Relationships between ultrastructural scrapie pathology and patterns of abnormal prion protein accumulation

M. Simmons, M. Jeffrey, C. Ersdal, 2004, Acta Neuropathologica.

Prion diseases are efficiently transmitted by blood transfusion in sheep.

N. Hunter, A. Chong, W. Goldmann, 2008, Blood.

Immunohistochemical features of PrP(d) accumulation in natural and experimental goat transmissible spongiform encephalopathies.

J. Langeveld, F. V. van Zijderveld, N. Hunter, 2006, Journal of comparative pathology.

Genotype-dependent Molecular Evolution of Sheep Bovine Spongiform Encephalopathy (BSE) Prions in Vitro Affects Their Zoonotic Potential*

J. Ironside, M. Head, M. Barria, 2014, The Journal of Biological Chemistry.

Characterization of strains of ovine transmissible spongiform encephalopathy with a short PrPd profiling method.

F. Chianini, S. Sisó, M. Dagleish, 2010, Journal of comparative pathology.

Vacuolar lesion profile in sheep scrapie: factors influencing its variation and relationship to disease-specific PrP accumulation.

N. Hunter, M. Simmons, F. Houston, 2002, Journal of comparative pathology.

Frequency and Distribution of Nerves in Scrapie-affected and Unaffected Peyer's Patches and Lymph Nodes

M. Jeffrey, G. McGovern, L. González, 2009, Veterinary pathology.

A non-invasive screen for infectivity in transmissible spongiform encephalopathies

S. Sisó, M. Jeffrey, B. Pollard, 2007, Gut.

Canine D163-PrP polymorphic variant does not provide complete protection against prion infection in small ruminant PrP context

J. Torres, J. Espinosa, J. L. Pitarch, 2021, Scientific Reports.

Immunological differences between susceptible and resistant sheep during the preclinical phase of scrapie infection.

F. Chianini, P. Steele, S. Hamilton, 2007, The Journal of general virology.

Prion Protein-Specific Antibodies that Detect Multiple TSE Agents with High Sensitivity

C. de Wolf, J. Langeveld, N. Hunter, 2014, PloS one.

Comparative Susceptibility of Sheep of Different Origins, Breeds and PRNP Genotypes to Challenge with Bovine Spongiform Encephalopathy and Scrapie

N. Hunter, W. Goldmann, J. Foster, 2015, PloS one.

Oral transmission of bse to vrq/vrq sheep in an experimental flock

S. Bellworthy, M. Simmons, M. Jeffrey, 2008, Veterinary Record.

Surveillance of hemorrhagic fever and/or neuroinvasive disease: challenges of diagnosis

S. Witkin, E. Sabino, C. Cirqueira, 2021, Revista de saude publica.

Goat K222-PrPC polymorphic variant does not provide resistance to atypical scrapie in transgenic mice

O. Andréoletti, L. Orge, J. Torres, 2016, Veterinary Research.

Susceptibility to Scrapie and Disease Phenotype in Sheep: Cross-Prnp Genotype Transmission with Natural Sources

F. Chianini, M. Dagleish, M. Jeffrey, 2013 .

Pathology and pathogenesis of bovine spongiform encephalopathy and scrapie.

M. Jeffrey, L. González, 2004, Current topics in microbiology and immunology.

Codon 141 polymorphisms of the ovine prion protein gene affect the phenotype of classical scrapie transmitted from goats to sheep

S. Cawthraw, T. Konold, Laura J Phelan, 2017, BMC Veterinary Research.

Immunohistochemical and biochemical characteristics of BSE and CWD in experimentally infected European red deer (Cervus elaphus elaphus).

P. Steele, S. Sisó, H. Reid, 2009, BMC veterinary research.

Experimental transmission of bovine spongiform encephalopathy to European red deer (Cervus elaphus elaphus)

F. Chianini, P. Steele, S. Hamilton, 2008, BMC Veterinary Research.

Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent

N. Hunter, S. Sisó, F. Houston, 2009, Neuropathology and applied neurobiology.

Susceptibility of European Red Deer (Cervus elaphus elaphus) to Alimentary Challenge with Bovine Spongiform Encephalopathy

J. Castilla, W. Goldmann, F. Chianini, 2015, PloS one.

Immunohistochemical and Biochemical Characteristics of Bse and Cwd in Experimentally Infected European Red Deer (cervus Elaphus Elaphus)

P. Steele, S. Sisó, H. Reid, 2022 .

Diagnostic pathology in microbial diseases of sheep or goats.

M. Dagleish, L. González, Julio Benavides, 2015, Veterinary microbiology.

Incidence of Infection in Prnp ARR/ARR Sheep following Experimental Inoculation with or Natural Exposure to Classical Scrapie

F. Chianini, S. Eaton, M. Dagleish, 2014, PloS one.

Variability in disease phenotypes within a single PRNP genotype suggests the existence of multiple natural sheep scrapie strains within Europe.

J. Langeveld, E. Monleón, C. Acín, 2010, The Journal of general virology.

BSE can propagate in sheep co-infected or pre-infected with scrapie

N. Hunter, A. Chong, W. Goldmann, 2021, Scientific Reports.

Increased immunohistochemical labelling for prion protein occurs in diverse neurological disorders of sheep: relevance for normal cellular PrP function.

G. McGovern, L. González, S. Martin, 2012, Journal of comparative pathology.

Idiopathic Brainstem Neuronal Chromatolysis (IBNC): a novel prion protein related disorder of cattle?

L. Terry, M. Jeffrey, L. González, 2008, BMC veterinary research.

Neuropathological changes correlate temporally but not spatially with selected neuromodulatory responses in natural scrapie

I. Ferrer, F. Chianini, S. Sisó, 2011, Neuropathology and applied neurobiology.

Pathogenetical Significance of Porencephalic Lesions Associated with Intracerebral 1 Inoculation of Sheep with the Bse Agent Title: 91 Characters including Spaces. Running Title: 38 Characters including Spaces

N. Hunter, S. Sisó, F. Houston, 2009 .

Pathology of SSLOW, a transmissible and fatal synthetic prion protein disorder, and comparison with naturally occurring classical transmissible spongiform encephalopathies

N. Makarava, I. Baskakov, R. Rohwer, 2014, Neuropathology and applied neurobiology.

A prion reduction filter does not completely remove endogenous prion infectivity from sheep blood

M. Turner, N. E. Appleford, J. Manson, 2015, Transfusion.

Discrimination of sheep susceptible and resistant to transmissible spongiform encephalopathies by an haplotype specific monoclonal antibody.

O. Andréoletti, N. Morel, J. Grassi, 2007, Journal of virological methods.