S. Rea

发表

An FTLD-associated SQSTM1 variant impacts Nrf2 and NF-κB signalling and is associated with reduced phosphorylation of p62

D. Scott, R. Layfield, A. Foster, 2019, Molecular and Cellular Neuroscience.

New insights into the role of sequestosome 1/p62 mutant proteins in the pathogenesis of Paget's disease of bone.

J. Walsh, Jiake Xu, R. Layfield, 2013, Endocrine reviews.

Proteasome inhibitors impair RANKL‐induced NF‐κB activity in osteoclast‐like cells via disruption of p62, TRAF6, CYLD, and IκBα signaling cascades

J. Walsh, N. Pavlos, Jiake Xu, 2009, Journal of cellular physiology.

SQSTM1 mutations--bridging Paget disease of bone and ALS/FTLD.

M. Searle, R. Layfield, S. Rea, 2014, Experimental cell research.

The Changing Presentation of Paget’s Disease of Bone in Australia, A High Prevalence Region

J. Walsh, T. Ratajczak, Suzanne Brown, 2017, Calcified Tissue International.

Paget disease of bone-associated UBA domain mutations of SQSTM1 exert distinct effects on protein structure and function

F. Gianfrancesco, T. Esposito, S. Ralston, 2014, Biochimica et biophysica acta.

Common susceptibility alleles and SQSTM1 mutations predict disease extent and severity in a multinational study of patients with Paget's disease

F. Gianfrancesco, T. Esposito, S. Ralston, 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Bafilomycin A1 Attenuates Osteoclast Acidification and Formation, Accompanied by Increased Levels of SQSTM1/p62 Protein

Hua-zi Xu, J. Walsh, N. Pavlos, 2016, Journal of cellular biochemistry.

A Novel Mutation (K378X) in the Sequestosome 1 Gene Associated With Increased NF‐κB Signaling and Paget's Disease of Bone With a Severe Phenotype

J. Walsh, J. Steer, Jiake Xu, 2006, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Sequestosome 1 Mutations in Paget's Disease of Bone in Australia: Prevalence, Genotype/Phenotype Correlation, and a Novel Non‐UBA Domain Mutation (P364S) Associated With Increased NF‐κB Signaling Without Loss of Ubiquitin Binding

J. Walsh, A. Magno, Jiake Xu, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Disulfiram Attenuates Osteoclast Differentiation In Vitro: A Potential Antiresorptive Agent

A. Qin, N. Pavlos, M. Zheng, 2015, PloS one.

Functional and structural consequences of TBK1 missense variants in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

R. L. Mancera, Krushna Sonar, S. Rea, 2022, Neurobiology of Disease.

ALS-FTLD associated mutations of SQSTM1 impact on Keap1-Nrf2 signalling

M. Searle, R. Layfield, B. Shaw, 2016, Molecular and Cellular Neuroscience.

The S349T mutation of SQSTM1 links Keap1/Nrf2 signalling to Paget's disease of bone.

B. K. Park, C. Goldring, M. Searle, 2013, Bone.

Mutant SQSTM1/p62 Signaling in Paget’s Disease of Bone

R. Layfield, S. Rea, 2016 .

Functional and structural consequences of TBK1 missense variants in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

R. L. Mancera, Krushna Sonar, S. Rea, 2022, Neurobiology of Disease.