T. Dal-Cim

发表

Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia

P. Negredo, R. León, Manuela G. López, 2013, Neuropharmacology.

Guanosine-5′-monophosphate induces cell death in rat hippocampal slices via ionotropic glutamate receptors activation and glutamate uptake inhibition

C. Tasca, T. Dal-Cim, S. Molz, 2009, Neurochemistry International.

In vitro 6-hydroxydopamine-induced toxicity in striatal, cerebrocortical and hippocampal slices is attenuated by atorvastatin and MK-801.

C. Tasca, D. Lanznaster, T. Dal-Cim, 2016, Toxicology in vitro : an international journal published in association with BIBRA.

Involvement of PI3K/Akt/GSK-3β and mTOR in the antidepressant-like effect of atorvastatin in mice.

A. Rodrigues, F. K. Ludka, C. Tasca, 2016, Journal of psychiatric research.

Guanosine prevents oxidative damage and glutamate uptake impairment induced by oxygen/glucose deprivation in cortical astrocyte cultures: involvement of A1 and A2A adenosine receptors and PI3K, MEK, and PKC pathways

C. Tasca, C. B. Nedel, K. A. de Oliveira, 2019, Purinergic Signalling.

Guanosine prevents nitroxidative stress and recovers mitochondrial membrane potential disruption in hippocampal slices subjected to oxygen/glucose deprivation

C. Tasca, M. Cunha, D. Lanznaster, 2016, Purinergic Signalling.

In vitro oxygen-glucose deprivation to study ischemic cell death.

C. Tasca, H. Cimarosti, T. Dal-Cim, 2015, Methods in molecular biology.

Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity.

A. Zamoner, C. Tasca, Vera Lúcia de Liz Oliveira Cavalli, 2014, Toxicology.

Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus

A. P. Costa, R. Prediger, F. K. Ludka, 2018, Neurotoxicity Research.

Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation

C. Tasca, D. Lanznaster, S. Vandresen-Filho, 2016, Neurotoxicity Research.

Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1–40 Administration in Mice

D. Souza, R. Prediger, E. Zimmer, 2016, Molecular Neurobiology.

Neuroprotective effect of guanosine against glutamate‐induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol‐3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition

Manuela G. López, A. Rodrigues, C. Tasca, 2011, Journal of neuroscience research.

Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca2+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake

C. Tasca, A.R.S. Santos, T. Dal-Cim, 2011, Neuroscience.

Guanosine and GMP increase the number of granular cerebellar neurons in culture: dependence on adenosine A2A and ionotropic glutamate receptors

C. Tasca, C. B. Nedel, V. Moura-Neto, 2019, Purinergic Signalling.

Atorvastatin Promotes Cytotoxicity and Reduces Migration and Proliferation of Human A172 Glioma Cells

F. K. Ludka, C. Tasca, C. B. Nedel, 2017, Molecular Neurobiology.

Guanosine promotes cytotoxicity via adenosine receptors and induces apoptosis in temozolomide-treated A172 glioma cells

C. Tasca, C. B. Nedel, T. Dal-Cim, 2017, Purinergic Signalling.

Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway

Manuela G. López, C. Tasca, J. Budni, 2012, Neurochemistry International.

Neonatal Isoflurane Exposure in Rats Impairs Short-Term Memory, Cell Viability, and Glutamate Uptake in Slices of the Frontal Cerebral Cortex, But Not the Hippocampus, in Adulthood

A. P. Costa, R. Prediger, F. K. Ludka, 2022, Neurotoxicity Research.

Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS

Manuela G. López, A. Rodrigues, C. Tasca, 2017, Molecular Neurobiology.

Neuroprotection Promoted by Guanosine Depends on Glutamine Synthetase and Glutamate Transporters Activity in Hippocampal Slices Subjected to Oxygen/Glucose Deprivation

C. Tasca, D. Lanznaster, S. Vandresen-Filho, 2016, Neurotoxicity Research.

Novel synthetic chalcones induces apoptosis in human glioblastoma cells.

A. Mascarello, L. D. Chiaradia-Delatorre, R. Yunes, 2016, Chemico-biological interactions.

Aloysia gratissima prevents cellular damage induced by glutamatergic excitotoxicity

M. Maraschin, C. Tasca, A. Zeni, 2014, The Journal of pharmacy and pharmacology.

Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.

M. Maraschin, A. Rodrigues, C. Tasca, 2011, Journal of ethnopharmacology.

Guanosine: a Neuromodulator with Therapeutic Potential in Brain Disorders

C. Tasca, D. Lanznaster, T. Piermartiri, 2016, Aging and disease.

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1–40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems

R. Prediger, C. Tasca, M. Farina, 2015, Neurotoxicity Research.

Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions

F. K. Ludka, C. Tasca, J. Egea, 2013, Journal of neurochemistry.

N-Methyl-d-aspartate Preconditioning Prevents Quinolinic Acid-Induced Deregulation of Glutamate and Calcium Homeostasis in Mice Hippocampus

C. Tasca, L. Constantino, S. Vandresen-Filho, 2015, Neurotoxicity Research.

Involvement of glutamatergic neurotransmission in the antidepressant-like effect of zinc in the chronic unpredictable stress model of depression

A. Rodrigues, C. Tasca, M. Moretti, 2016, Journal of Neural Transmission.

Atorvastatin Protects from Aβ1–40-Induced Cell Damage and Depressive-Like Behavior via ProBDNF Cleavage

A. Rodrigues, F. K. Ludka, C. Tasca, 2017, Molecular Neurobiology.

echanisms underlying the neurotoxicity induced by lyphosate-based herbicide in immature rat hippocampus : nvolvement of glutamate excitotoxicity

A. Zamoner, C. Tasca, T. Dal-Cim, 2014 .

Glutamate-induced Toxicity in Hippocampal Slices Involves Apoptotic Features and p38MAPK Signaling

R. Leal, C. Tasca, H. Decker, 2007, Neurochemical Research.

Acute atorvastatin treatment exerts antidepressant-like effect in mice via the l-arginine–nitric oxide–cyclic guanosine monophosphate pathway and increases BDNF levels

A. Rodrigues, F. K. Ludka, C. Tasca, 2013, European Neuropsychopharmacology.

Atorvastatin evokes a serotonergic system-dependent antidepressant-like effect in mice

A. Rodrigues, F. K. Ludka, C. Tasca, 2014, Pharmacology Biochemistry and Behavior.

Atorvastatin and Fluoxetine Prevent Oxidative Stress and Mitochondrial Dysfunction Evoked by Glutamate Toxicity in Hippocampal Slices

F. K. Ludka, C. Tasca, L. Constantino, 2017, Molecular Neurobiology.