Xinyu You

发表

Discovery of novel N-(5-(tert-butyl)isoxazol-3-yl)-N'-phenylurea analogs as potent FLT3 inhibitors and evaluation of their activity against acute myeloid leukemia in vitro and in vivo.

Q. Lei, Lidan Zhang, Yong Xia, 2015, Bioorganic & medicinal chemistry.

Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents.

Yuquan Wei, Lidan Zhang, Yong Xia, 2013, Bioorganic & medicinal chemistry letters.

Benzothiazinethione is a potent preclinical candidate for the treatment of drug-resistant tuberculosis

Yuquan Wei, Lidan Zhang, Yongxia Zhu, 2016, Scientific Reports.

Synthesis and antitubercular evaluation of 4-carbonyl piperazine substituted 1,3-benzothiazin-4-one derivatives.

Q. Lei, Lidan Zhang, Yongxia Zhu, 2015, Bioorganic & medicinal chemistry letters.

Mannosylated liposomes improve therapeutic effects of paclitaxel in colon cancer models

Q. Lei, Lidan Zhang, Yong Xia, 2017, Journal of microencapsulation.

Discovery of imidazo[2,1-b]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents.

Yuquan Wei, Hong Tang, Q. Lei, 2015, Journal of medicinal chemistry.

Discovery and structure-activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitors.

Yuquan Wei, Sheng-yong Yang, Lidan Zhang, 2014, Bioorganic & medicinal chemistry letters.

The Preparation and Evaluation of Water-Soluble SKLB610 Nanosuspensions with Improved Bioavailability

Yong Xia, Xuejiao Song, Luoting Yu, 2013, AAPS PharmSciTech.

Design, synthesis and biological evaluation of novel 1-methyl-3-oxo-2,3,5,6,7,8-hexahydroisoquinolins as potential EZH2 inhibitors

Lidan Zhang, Xuejiao Song, Ningyu Wang, 2015 .

Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Q. Lei, Lidan Zhang, 2016, Scientific Reports.

A novel benzothiazinethione analogue SKLB-TB1001 displays potent antimycobacterial activities in a series of murine models.

Yuquan Wei, Lidan Zhang, Ningyu Wang, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

ZLD1122, a novel EZH2 and EZH1 small molecular inhibitor, blocks H3K27 methylation and diffuse large B cell lymphoma cell growth

Q. Lei, Lidan Zhang, Yong Xia, 2016 .

A novel VEGFR inhibitor ZLF-095 with potent antitumor activity and low toxicity

Q. Lei, Lidan Zhang, Xuejiao Song, 2023, Heliyon.

A new series of HCV inhibitors based on a 2-(thieno[2,3b]pyridin-2-yl)-1,3,4-oxadiazole scaffold

Hong Tang, Lidan Zhang, Yongxia Zhu, 2016 .

Corrigendum: Selective inhibition of EZH2 by ZLD1039 blocks H3K27methylation and leads to potent anti-tumor activity in breast cancer

Yuquan Wei, Lidan Zhang, Yong Xia, 2016, Scientific Reports.

Discovery of imidazo[2,1-b]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents.

Yuquan Wei, Hong Tang, Lidan Zhang, 2015, Journal of medicinal chemistry.