K. Ohmori

发表

Histamine H1 receptor antagonist blocks histamine-induced proinflammatory cytokine production through inhibition of Ca2+-dependent protein kinase C, Raf/MEK/ERK and IKK/I kappa B/NF-kappa B signal cascades.

T. Tamura, M. Matsubara, K. Ohmori, 2005, Biochemical pharmacology.

Histamine H1 Receptor-Stimulated Interleukin 8 and Granulocyte Macrophage Colony-Stimulating Factor Production by Bronchial Epithelial Cells Requires Extracellular Signal-Regulated Kinase Signaling via Protein Kinase C

M. Matsubara, K. Ohmori, K. Hasegawa, 2006, International Archives of Allergy and Immunology.

Effect of terfenadine and KW-4679, a novel antiallergic compound, on action potential of guinea pig ventricular myocytes.

T. Mori, Y. Kato, K. Ohmori, 1996, Japanese journal of pharmacology.

Pharmacological, pharmacokinetic and clinical properties of olopatadine hydrochloride, a new antiallergic drug.

Satoshi Kobayashi, K. Hayashi, T. Yamazaki, 2002, Japanese journal of pharmacology.

Pharmacological studies of diacerein in animal models of inflammation, arthritis and bone resorption.

Tomomi Shirai, T. Tamura, N. Kosaka, 2002, European journal of pharmacology.

[Effect of KW-4679, a novel antiallergic drug, on platelet-activating factor (PAF)-induced bronchoconstriction, airway hyperresponsiveness and pulmonary cell accumulation in guinea pigs].

H. Ishii, S. Kitamura, K. Ohmori, 1995, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Effect of oxatomide on experimental allergic rhinitis in guinea pigs.

T. Kaise, K. Ohmori, Y. Akamatsu, 1998, Japanese journal of pharmacology.

抗アレルギー薬KW-4679の薬理作用(第1報)受身皮膚アナフィラキシーおよび実験的喘息に及ぼす影響

S. Kitamura, K. Ohmori, Yasuo Sasaki, 1995 .

[Recent development of new drugs for the treatment of allergic diseases].

D. Harada, H. Manabe, E. Ohshima, 2004, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

The inhaled administration of KF19514, a phosphodiesterase 4 and 1 inhibitor, prevents antigen-induced lung inflammation in guinea pigs.

H. Manabe, H. Kawasaki, K. Akuta, 2000, Pulmonary pharmacology & therapeutics.

Effect of zaldaride maleate, an antidiarrheal compound, on fecal pellet output induced by hyperpropulsion in gastrointestine of rats.

K. Ohmori, N. Aikawa, 2000, Japanese journal of pharmacology.

Oxatomide inhibits the release of chemical mediators from human lung tissues and from granulocytes.

H. Manabe, S. Yoshida, H. Tomioka, 1988, International archives of allergy and applied immunology.

Attenuation of methylation of catecholamines and treatment with a coenzyme of catechol-O-methyltransferase in Spontaneously Hypertensive Rats (SHR)

T. Santa, K. Imai, M. Tsunoda, 1999 .

Effects on the Reactive Oxygen Species of Erdosteine and its Metabolite in vitro

T. Kaise, K. Ohmori, H. Hosoe, 2002, Arzneimittelforschung.

Protective Effect of Erdosteine Against Hypochlorous Acid‐induced Acute Lung Injury and Lipopolysaccharide‐induced Neutrophilic Lung Inflammation in Mice

K. Ohmori, Ken-Ichi. Hayashi, H. Hosoe, 2000, The Journal of pharmacy and pharmacology.

Mucolytic and Antitussive Effects of Erdosteine

T. Miyata, K. Takahama, H. Kai, 1999, The Journal of pharmacy and pharmacology.

The effect of erdosteine and its active metabolite on reactive oxygen species production by inflammatory cells

H. Manabe, K. Miyake, K. Akuta, 1999, Inflammation Research.

KW‐4679‐induced inhibition of tachykininergic contraction in the guinea‐pig bronchi by prejunctional inhibition of peripheral sensory nerves

K. Ohmori, Y. Sasaki, T. Ikemura, 1996, British journal of pharmacology.

Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen–antibody reaction in guinea pigs

A. Ishii, A. Karasawa, T. Kaise, 2001 .

The effect of KW-4679, an antiallergic drug, on experimental allergic rhinitis in guinea pigs: effects on nasal blockage.

Y. Sakakura, K. Ukai, T. Kaise, 1995, Japanese journal of pharmacology.

Antioxidant effects of calcium antagonists in rat brain homogenates.

K. Nagashima, K. Ohmori, K. Yao, 2000, Biological & pharmaceutical bulletin.

[Effect of olopatadine hydrochloride, a novel antiallergic agent, on the QT interval in dogs].

N. Kosaka, S. Ichikawa, H. Kobayashi, 2001, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

TMC-66, a new endothelin converting enzyme inhibitor produced by Streptomyces sp. A5008.

Y. Asai, K. Takahashi, S. Komatsubara, 1999, The Journal of antibiotics.

Involvement of neuropeptides in the allergic nasal obstruction in guinea pigs.

A. Ishii, A. Karasawa, T. Kaise, 2001, Japanese journal of pharmacology.

Effect of KW-4679, an orally active anti-allergic drug, on antigen-induced airway hyperresponsiveness in actively sensitized guinea pigs.

H. Manabe, H. Kawasaki, K. Ohmori, 1996, Japanese journal of pharmacology.

Benidipine Inhibits Apoptosis During Ischaemic Acute Renal Failure in Rats

S. Nishikawa, K. Nagashima, K. Ohmori, 2000, The Journal of pharmacy and pharmacology.

Roles of mast cells and sensory nerves in cutaneous vascular hyperpermeability and scratching behavior induced by poly-L-arginine in rats.

H. Satō, A. Ishii, A. Karasawa, 2001, European journal of pharmacology.

Inhibitory effect of olopatadine hydrochloride (KW-4679), a novel antiallergic drug, on peptide leukotriene release from human eosinophils

A. Ishii, A. Karasawa, K. Ohmori, 2001 .

New bronchodilators. 3. Imidazo[4,5-c][1,8]naphthyridin-4(5H)-ones.

H. Kase, S. Kitamura, M. Ichimura, 1992, Journal of medicinal chemistry.

Inhibitory effect of KW-4679, an anti-allergic drug, on tachykinin-mediated airway response induced by electrical vagal stimulation in guinea pigs.

H. Ishii, K. Ohmori, Y. Sasaki, 1996, Japanese journal of pharmacology.

Synthesis and aldose reductase inhibitory activity of acetic acid derivatives of pyrrolo[1,2-c]imidazole

K. Ohmori, N. Nomura, K. Ogawa, 1993 .

A novel synthesis and potent antiinflammatory activity of 4-hydroxy-2(1H)-oxo-1-phenyl-1,8-naphthyridine-3-carboxamides.

T. Tamura, F. Suzuki, K. Ohmori, 1992, Journal of medicinal chemistry.

Protective effects of benidipine on hydrogen peroxide‐induced injury in rat isolated hearts

K. Nagashima, K. Ohmori, K. Yao, 2003, The Journal of pharmacy and pharmacology.

New bronchodilators. 1. 1,5-Substituted 1H-imidazo[4,5-c]quinolin-4(5H)-ones.

S. Kitamura, F. Suzuki, H. Manabe, 1992, Journal of medicinal chemistry.

Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivatives.

H. Ishii, H. Satō, N. Hirayama, 1992, Journal of medicinal chemistry.

Possible involvement of 5-HT4 receptors, in addition to 5-HT3 receptors, in the emesis induced by high-dose cisplatin in Suncus murinus.

A. Ishii, A. Karasawa, K. Ohmori, 2001, Japanese journal of pharmacology.

Acceleration by KW-5092 of intestinal motility associated with acetylcholine release in vivo.

T. Kanematsu, H. Kobayashi, K. Ohmori, 2000, Japanese journal of pharmacology.

[Pharmacological studides on 5-hydroxy-L-tryptophan (L-5HTP). Interaction between L-5HTP and p-CPA].

H. Marumo, K. Ohmori, T. Kojima, 1976, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

The effects of olopatadine hydrochloride on the number of scratching induced by repeated application of oxazolone in mice.

T. Tamura, H. Manabe, T. Amano, 2005, European journal of pharmacology.

Effect of Olopatadine and Other Histamine H1 Receptor Antagonists on the Skin Inflammation Induced by Repeated Topical Application of Oxazolone in Mice

T. Tamura, S. Masaki, A. Karasawa, 2005, Pharmacology.

Differential regulation of IL-4 expression and degranulation by anti-allergic olopatadine in rat basophilic leukemia (RBL-2H3) cells.

S. Masaki, A. Karasawa, M. Matsubara, 2004, Biochemical pharmacology.

Effects of orally administered olopatadine hydrochloride on the ocular allergic reaction in rats

Hitoshi Sato, I. Miki, Kazuo T. Suzuki, 2003 .

Properties of Olopatadine Hydrochloride, a New Antiallergic/Antihistamine Drug

T. Tamura, S. Masaki, A. Karasawa, 2004, Arzneimittelforschung.

KW-4679, an antiallergic drug, inhibits the production of inflammatory lipids in human polymorphonuclear leukocytes and guinea pig eosinophils.

I. Miki, H. Ishii, H. Kase, 1996, International archives of allergy and immunology.

Jararhagin and Jaracetin: Novel Snake Venom Inhibitors of the Integrin Collagen Receptor, α2β1

C. Ward, M. Berndt, R. Andrews, 1995 .

Y. Murakumo, N. Asai, Masahide Takahashi, 2012, Biochemical and biophysical research communications.

Olopatadine Suppresses the Migration of THP-1 Monocytes Induced by S100A12 Protein

S. Kaneko, T. Tamura, K. Ohmori, 2006, Mediators of inflammation.

Effects of olopatadine hydrochloride on the cutaneous vascular hyperpermeability and the scratching behavior induced by poly-L-arginine in rats.

A. Ishii, A. Karasawa, T. Kaise, 2001, Japanese journal of pharmacology.

Effects of KW-4679, a new orally active antiallergic drug, on antigen-induced bronchial hyperresponsiveness, airway inflammation and immediate and late asthmatic responses in guinea pigs.

H. Ishii, S. Kitamura, H. Manabe, 1996, International archives of allergy and immunology.

Effect of zaldaride maleate, an antidiarrheal compound, on 16,16-dimethyl prostaglandin E2-induced intestinal ion secretion in rats.

A. Karasawa, K. Ohmori, N. Aikawa, 2000, Japanese journal of pharmacology.

Effect of sodium dipropylacetate on conflict behavior in rats.

K. Shuto, H. Marumo, K. Ohmori, 1980, Japanese journal of pharmacology.

Effect of zaldaride maleate, an antidiarrheal compound, on visceral pain reflex induced by small intestinal distention in anesthetized rats.

K. Ohmori, N. Aikawa, 1999, Japanese journal of pharmacology.

Monoclonal antibodies distinctively recognizing the subtypes of inositol 1,4,5‐trisphosphate receptor: Application to the studies on inflammatory cells

K. Mikoshiba, M. Yamamoto-Hino, T. Monkawa, 1994, FEBS letters.

Inhibitory effect of olopatadine hydrochloride on the sneezing response induced by intranasal capsaicin challenge in guinea pigs.

A. Ishii, A. Karasawa, T. Kaise, 2001, Japanese journal of pharmacology.

Effects of zaldaride maleate, an antidiarrheal compound, on intracellular Ca2+-mediated short-circuit current response in the rat colonic mucosa.

A. Karasawa, K. Ohmori, N. Aikawa, 2000, Japanese Journal of Pharmacology.

Inhibitory effect of oxatomide on oxygen-radical generation and peptide-leukotriene release from guinea pig eosinophils.

H. Manabe, K. Ohmori, K. Akuta-Ohnuma, 1998, Arzneimittel-Forschung.

Anti-inflammatory and bronchodilator properties of KF19514, a phosphodiesterase 4 and 1 inhibitor.

H. Kase, S. Kitamura, M. Ichimura, 1997, European journal of pharmacology.

[Pharmacological studies on oxatomide (KW-4354): (2) Effect on the experimental models of the type 1-type 4 allergic reactions].

H. Ishii, T. Hirayama, K. Shuto, 1982, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Jararhagin and jaracetin: novel snake venom inhibitors of the integrin collagen receptor, alpha 2 beta 1.

C. Ward, M. De Luca, M. Berndt, 1995, Biochemical and Biophysical Research Communications - BBRC.

Effects of Diacerein on Indomethacin-Induced Gastric Ulceration

T. Tamura, K. Ohmori, T. Yokoyama, 2001, Pharmacology.

Effects of Endothelin B Antagonist RES−701−1 on Endothelin‐induced Contractile Responses In‐vivo and In‐vitro in Guinea‐pigs

Y. Matsuda, Takeo Tanaka, S. Kitamura, 1996, The Journal of pharmacy and pharmacology.

Antiinflammatory and antiallergic effects of a novel metabolite of Nocardiopsis sp. as a potent protein kinase C inhibitor from microbial origin.

H. Ishii, H. Kase, T. Tamura, 1988, Arzneimittel-Forschung.

Effect of Oxatomide, an Antiallergic Agent, on QT Interval in Dogs

N. Kosaka, K. Sakai, K. Iwamoto, 2001, Arzneimittelforschung.

[The effect of KW-4679, an antiallergic drug, on experimental allergic rhinitis].

H. Manabe, T. Kaise, K. Ohmori, 1995, Arerugi = [Allergy].

Synthesis and Antiallergic Activity of 11‐(Aminoalkylidene)‐6,11‐ dihydrodibenz(b,e)oxepin Derivatives.

Hiroshi Sato, H. Ishii, N. Hirayama, 1992 .

Pharmacological properties of a new antiallergic agent KW-4679

H. Ishii, T. Tamura, H. Satoh, 1988 .

Rhein, an active metabolite of diacerein, suppresses the interleukin-1alpha-induced proteoglycan degradation in cultured rabbit articular chondrocytes.

T. Tamura, K. Ohmori, K. Ohmori, 2001, Japanese journal of pharmacology.