T. Watanabe

发表

Antioxidative compounds isolated from safflower (Carthamus tinctorius L.) oil cake.

H. Okuyama, A. Nagatsu, J. Sakakibara, 1997, Chemical & pharmaceutical bulletin.

Human cell clones, RSa and UVr-1, differing in their capability for UV-induced virus reactivation and phenotypic mutation.

N. Suzuki, N. Inaba, H. Takamizawa, 1994, Mutation research.

Metabolic activation of 2- and 3-nitrodibenzopyranone isomers and related compounds by rat liver S9 and the effect of S9 on the mutational specificity of nitrodibenzopyranones.

J. Lewtas, M. Takashima, T. Hirayama, 1997, Mutation research.

Comparison of the mutational specificity induced by environmental genotoxin nitrated polycyclic aromatic hydrocarbons in Salmonella typhimurium his genes.

M. Takashima, T. Hirayama, T. Watanabe, 1997, Mutation research.

Mutagenicity of nitrodibenzopyranones in the Salmonella plate-incorporation and microsuspension assays.

J. Lewtas, D. DeMarini, L. Ball, 1995, Mutation research.

Metabolic activation of nitrodibenzofurans by rat liver in Salmonella/mutagenicity test.

T. Hirayama, T. Watanabe, H. Kaji, 1994, Mutation research.

Relationships between structure of nitrated arenes and their mutagenicity in Salmonella typhimurium; 2- and 2,7-nitro substituted fluorene, phenanthrene and pyrene.

Y. Fujioka, T. Hirayama, T. Watanabe, 1988, Mutation research.

Quantification of two aromatic amine mutagens, PBTA-1 and PBTA-2, in the yodo river system.

T. Sugimura, K. Wakabayashi, H. Nukaya, 1999, Environmental health perspectives.

Isolation and chemical--structural identification of a novel aromatic amine mutagen in an ozonized solution of m-phenylenediamine.

T. Hirayama, T. Watanabe, H. Kami, 2000, Chemical research in toxicology.

Isolation and identification of a new 2-phenylbenzotriazole-type mutagen (PBTA-3) in the Nikko river in Aichi, Japan.

T. Sugimura, K. Wakabayashi, H. Nukaya, 2000, Chemical research in toxicology.

Potent and selective inhibition of the human Na+/H+ exchanger isoform NHE1 by a novel aminoguanidine derivative T-162559.

T. Kawamoto, K. Kusumoto, H. Kimura, 2001, European journal of pharmacology.

Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila.

E. Takahashi, H. Hayatsu, T. Negishi, 2001, Mutation research.

Studies on nonpeptide angiotensin II receptor antagonists. III. Synthesis and biological evaluation of 5-alkylidene-3,5-dihydro-4H-imidazol-4-one derivatives.

A. Fujimori, M. Shibasaki, O. Inagaki, 1998, Chemical & pharmaceutical bulletin.

Synthesis and biological activity of novel 2-(alpha-alkoxyimino)benzylpyridine derivatives as K+ channel openers.

S. Yamamoto, T. Maekawa, S. Ikeda, 1997, Chemical & pharmaceutical bulletin.

Synthesis and biological activity of novel 1,3-benzoxazine derivatives as K+ channel openers.

S. Yamamoto, M. Shiraishi, S. Hashiguchi, 1996, Chemical and pharmaceutical bulletin.

Synthesis and biological evaluation of 1,2,3,4-tetrahydroisoquinoline derivatives as potent and selective M2 muscarinic receptor antagonists.

T. Shibanuma, T. Watanabe, I. Kinoyama, 1999, Chemical & pharmaceutical bulletin.

Synthesis and biological evaluation of phenylacetyl derivatives having low central nervous system permeability as potent and selective M2 muscarinic receptor antagonists.

A. Kakefuda, A. Tanaka, H. Shibata, 1998, Chemical & pharmaceutical bulletin.

Synthesis of novel succinamide derivatives having the 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one skeleton as potent and selective M2 muscarinic receptor antagonists. I.

A. Kakefuda, H. Shibata, T. Watanabe, 1997, Chemical & pharmaceutical bulletin.

Genotoxicity in vivo of phenazine and aminophenazines assayed in the wing spot test and the DNA-repair test with Drosophila melanogaster.

M. Arima, T. Hirayama, T. Watanabe, 1996, Mutation research.

Synthesis of 2-deoxy-2-[(2,2-difluoro-3-hydroxytetradecanoyl)amino]-3-O- [(R)-3-(tetradecanoyloxy)tetradecanoyl]-D-glucopyranose 4-phosphate.

M. Shiozaki, T. Watanabe, T. Hiraoka, 1991, Journal of medicinal chemistry.

Synthesis and biological activity of 7 beta-(2-amino-2-carboxy)-ethylthioacetamido-7 alpha-methoxycephalosporin derivatives.

S. Inouye, S. Omoto, T. Niida, 1983, The Journal of antibiotics.

Mutagenicity of nitro derivatives produced by exposure of dibenzofuran to nitrogen oxides.

T. Hirayama, T. Watanabe, 1992, Mutation research.

Chemo- and enzymatic synthesis of partially and fully N-deacetylated 4-methylumbelliferyl chitobiosides: fluorogenic substrates for chitinase.

M. Hashimoto, K. Tokuyasu, Y. Honda, 2000, Bioorganic & medicinal chemistry letters.

Relationship between mutagenic potency in Salmonella typhimurium strains and the chemical structure of nitro biphenyls.

Y. Fujioka, H. Kusakabe, T. Hirayama, 1986, Mutation research.

Radioresistant DNA synthesis in fibroblast cell lines derived from LEC strain rats.

M. Hayashi, T. Okui, S. Arai, 1996, Mutation research.

Mutagenic activity of surface soil and quantification of 1,3-, 1,6-, and 1,8-dinitropyrene isomers in soil in Japan.

K. Wakabayashi, N. Sera, S. Goto, 2000, Chemical research in toxicology.

Identification of 1,6- and 1,8-dinitropyrene isomers as major mutagens in organic extracts of soil from Osaka, Japan.

K. Wakabayashi, T. Hirayama, T. Watanabe, 1998, Chemical research in toxicology.

Synthetic cephalosporins. II. The synthesis and oral activity of 7-[R-2-amino-2-(3-chloro-4-hydroxyphenyl)acetamido]-3-methylthio-3- cephem-4-carboxylic acid and related compounds.

M. Hatanaka, T. Watanabe, H. Nitta, 1987, The Journal of antibiotics.

Synthesis and immunological activity of 5,6,6a,8,9,11a-hexahydronaphth[1',2':4,5]imidazo[2,1-b]thiazoles and 5,6,6a,9,10,11a-hexahydroanaphth[2',1':4,5]imidazo[2,1-b]thiazoles.

A. Takénaka, H. Fukushima, K. Koyano, 1980, Journal of medicinal chemistry.

Mutagenicity of the reaction products of dibenzo-p-dioxin with nitrogen oxides.

T. Hirayama, T. Watanabe, M. Ikeda, 1992, Mutation research.

Mutagenic reactivities of 3,4-dinitrobiphenyl derivatives.

H. Kusakabe, T. Hirayama, T. Watanabe, 1987, Mutation research.

Mutagenicity of commercial hair dyes and detection of 2,7-diaminophenazine.

T. Hirayama, T. Watanabe, S. Fukui, 1990, Mutation research.

High-performance liquid chromatography-fluorescence determination of dinitropyrenes in soil after column chromatographic clean-up and on-line reduction.

K. Wakabayashi, T. Hirayama, T. Watanabe, 1999, Journal of chromatography. A.

Mutagenic effects of cadmium on mammalian oocyte chromosomes.

A. Endo, T. Shimada, T. Watanabe, 1979, Mutation research.

Metabolic activation of 2,4-dinitrobiphenyl derivatives for their mutagenicity in Salmonella typhimurium TA98.

T. Hirayama, T. Watanabe, K. Iguchi, 1990, Mutation research.

Synthesis of 2-phenylbenzotriazole-type mutagens, PBTA-5 and PBTA-6, and their detection in river water from Japan.

T. Sugimura, K. Wakabayashi, T Sugimura, 2001, Mutation research.

Identification of 2-[2-(acetylamino)-4-amino-5-methoxyphenyl]-5-amino-7-bromo-4-chloro-2H-benzotriazole (PBTA-4) as a potent mutagen in river water in Kyoto and Aichi prefectures, Japan.

T. Sugimura, K. Wakabayashi, T Sugimura, 2001, Mutation research.

Mutagenicity of nitro- and amino-substituted phenazines in Salmonella typhimurium.

T. Hirayama, T. Watanabe, S. Fukui, 1989, Mutation research.

Studies on nonpeptide angiotensin II receptor antagonists. II. Synthesis and biological evaluation of 5H-pyrazolo[1,5-b][1,2,4]triazole derivatives with a C-linked oxygen functional group at the 6-position.

A. Fujimori, H. Kurihara, M. Shibasaki, 1998, Chemical & pharmaceutical bulletin.

Antihypertensive and cardiovascular effects of a new potassium channel opener, TCV-295, in rats and dogs.

K. Kusumoto, M. Shiraishi, T. Watanabe, 1994, Journal of cardiovascular pharmacology.