J. Kotthaus

发表

Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).

D. Garbe‐Schönberg, F. Bittner, D. Schade, 2011, The Biochemical journal.

MS³ fragmentation patterns of monomethylarginine species and the quantification of all methylarginine species in yeast using MRM³.

Ted M. Lakowski, Dylan Thomas, T. Lakowski, 2013, Journal of proteomics.

The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs.

F. Bittner, R. Mendel, B. Clement, 2008, Journal of medicinal chemistry.

New Prodrugs of the Antiprotozoal Drug Pentamidine

D. Schade, B. Clement, W. Raasch, 2011, ChemMedChem.

Synthesis and biological evaluation of L-valine-amidoximeesters as double prodrugs of amidines.

S. Wolffram, D. Schade, B. Clement, 2011, Bioorganic & medicinal chemistry.

Incorporation of neutral C-terminal residues in 3-amidinophenylalanine-derived matriptase inhibitors.

T. Steinmetzer, B. Clement, A. Schweinitz, 2009, Bioorganic & medicinal chemistry letters.

Development of novel potent orally bioavailable oseltamivir derivatives active against resistant influenza A.

O. Koch, D. Schade, M. Schmidtke, 2014, Journal of medicinal chemistry.

Analysis of highly potent amidine containing inhibitors of serine proteases and their N-hydroxylated prodrugs (amidoximes)

T. Steinmetzer, A. van de Locht, B. Clement, 2011, Journal of enzyme inhibition and medicinal chemistry.

New 1H-Pyrazole-4-carboxamides with Antiplatelet Activity.

J. Kotthaus, K. Rehse, Laleh Khadembashi, 2009 .

New 1H‐Pyrazole‐4‐Carboxamides with Antiplatelet Activity

J. Kotthaus, K. Rehse, Laleh Khadembashi, 2009, Archiv der Pharmazie.

Zanamivir Amidoxime- and N-Hydroxyguanidine-Based Prodrug Approaches to Tackle Poor Oral Bioavailability.

D. Schade, M. Schmidtke, A. Hoffmann, 2015, Journal of pharmaceutical sciences.

Prodrug design for the potent cardiovascular agent Nω-hydroxy-L-arginine (NOHA): synthetic approaches and physicochemical characterization.

D. Schade, B. Clement, J. Kotthaus, 2011, Organic & biomolecular chemistry.

Highly Potent and Selective Substrate Analogue Factor Xa Inhibitors Containing D‐Homophenylalanine Analogues as P3 Residue: Part 2

T. Steinmetzer, U. Stürzebecher, B. Clement, 2007, ChemMedChem.

Synthesis and physicochemical characterization of novel 6-aminopyrido[3,4-c][1,9]phenanthrolines as aza-analogs of benzo[c]phenanthridines

B. Clement, C. Meier, U. Girreser, 2012 .

The Peptidylglycine α‐Amidating Monooxygenase (PAM): A Novel Prodrug Strategy for Amidoximes and N‐Hydroxyguanidines?

D. Schade, B. Clement, J. Kotthaus, 2009, ChemMedChem.

Designing modulators of dimethylarginine dimethylaminohydrolase (DDAH): A focus on selectivity over arginase

D. Schade, B. Clement, J. Kotthaus, 2012, Journal of enzyme inhibition and medicinal chemistry.

Metabolism and distribution of two highly potent and selective peptidomimetic inhibitors of matriptase

D. Schade, T. Steinmetzer, A. van de Locht, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC).

D. Garbe‐Schönberg, F. Bittner, D. Schade, 2011, The Biochemical journal.