H. Hashimoto

The direct PAK1 inhibitor, TAT-PAK18, blocks preferentially the growth of human ovarian cancer cell lines in which PAK1 is abnormally activated by autophosphorylation at Thr 423.

T. Sudo, H. Maruta, R. Nishimura, 2010, Drug discoveries & therapeutics.

Ivermectin inactivates the kinase PAK1 and blocks the PAK1-dependent growth of human ovarian cancer and NF2 tumor cell lines.

Shanta M. Messerli, T. Sudo, S. Messerli, 2009, Drug discoveries & therapeutics.