K. Locker

Quantitative determination of L-775,606, a selective 5-hydroxytryptamine 1D agonist, in rat plasma using automated sample preparation and detection by liquid chromatography-tandem mass spectrometry.

A. Watt, D. Morrison, K. Locker, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Fluorination of 3-(3-(piperidin-1-yl)propyl)indoles and 3-(3-(piperazin-1-yl)propyl)indoles gives selective human 5-HT1D receptor ligands with improved pharmacokinetic profiles.

A. Pike, H. Broughton, I. Collins, 1999, Journal of medicinal chemistry.

An Increased Throughput Method for the Determination of Partition Coefficients

A. Watt, L. Hitzel, K. Locker, 2000, Pharmaceutical Research.

2-Aryl indole NK1 receptor antagonists: optimisation of indole substitution.

K. Tsao, C. Swain, G. Hollingworth, 2001, Bioorganic & medicinal chemistry letters.

Higher throughput bioanalysis by automation of a protein precipitation assay using a 96-well format with detection by LC-MS/MS.

A P Watt, D Morrison, K L Locker, 2000, Analytical chemistry.

Substance P (Neurokinin 1) Receptor Antagonists Enhance Dorsal Raphe Neuronal Activity

M. Rigby, C. Swain, K. Maubach, 2002, The Journal of Neuroscience.

Determination of the in vitro metabolism of (+)- and (-)-epibatidine.

A. Watt, D. Morrison, L. Hitzel, 2000, Journal of chromatography. A.

Identification of metabolites of a substance P (neurokinin 1 receptor) antagonist in rat hepatocytes and rat plasma.

R. Mortishire-Smith, U. Gerhard, Sanjeev Kumar, 2002, Drug Metabolism And Disposition.