S. Köcher

发表

Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1

K. Rothkamm, E. Dikomey, C. Petersen, 2016, Oncotarget.

A Lack of Effectiveness in the ATM-Orchestrated DNA Damage Response Contributes to the DNA Repair Defect of HPV-Positive Head and Neck Cancer Cells

K. Rothkamm, M. Kriegs, C. Petersen, 2022, Frontiers in Oncology.

Patient derived ex vivo tissue slice cultures demonstrate a profound DNA double-strand break repair defect in HPV-positive oropharyngeal head and neck cancer.

K. Rothkamm, M. Kriegs, C. Petersen, 2022, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice.

K. Rothkamm, R. Reimer, E. Dikomey, 2016, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair

C. Bokemeyer, H. Huland, K. Rothkamm, 2020, Cancers.

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation

C. Oing, E. Dikomey, C. Petersen, 2015, Nucleic acids research.

Sorafenib inhibits cell growth but fails to enhance radio- and chemosensitivity of glioblastoma cell lines

K. Rothkamm, E. Dikomey, M. Kriegs, 2016, Oncotarget.

Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.

T. Dörk, N. Bogdanova, M. Baumann, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Fully automated counting of DNA damage foci in tumor cell culture: A matter of cell separation.

K. Rothkamm, C. Petersen, W. Mansour, 2021, DNA repair.

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase

J. Dahm-Daphi, G. Rohaly, E. Dikomey, 2012, Nucleic acids research.

Role of ATM (ataxia telangiectasia mutated) and Artemis proteins for the repair of DNA double-strand breaks by homologous recombination in mammalian cells

S. Köcher, 2011 .

Radiation DNA damage and use in cancer/therapeutics-translation of radiation modifiers

K. Rothkamm, E. Dikomey, M. Kriegs, 2016 .

Kinomic comparison of snap frozen and ex vivo-cultured head and neck tumors.

K. Rothkamm, M. Kriegs, C. Petersen, 2021, Oral oncology.

A functional ex vivo assay to detect PARP1‐EJ repair and radiosensitization by PARP‐inhibitor in prostate cancer

T. Schlomm, B. Beyer, T. Lange, 2019, International journal of cancer.

ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks.

J. Dahm-Daphi, M. Kriegs, S. Köcher, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

K. Rothkamm, M. Kriegs, A. Parplys, 2016, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Dual PI3K/mTOR Inhibitor NVP-BEZ235 Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Due to Suppressed Double-Strand Break (DSB) Repair by Non-Homologous End Joining

A. Arenz, E. Dikomey, A. Wittig, 2020, Cancers.

Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1

K. Rothkamm, K. Stölzel, M. Kriegs, 2023, Clinical and translational radiation oncology.

p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation

J. Dahm-Daphi, G. Rohaly, E. Dikomey, 2013, Oncogene.